Product Description
Eighty of the world's leading M.E./CFS authorities havecontributed their knowledge to produce a 750-page encyclopedia on thedisease process that may be one of the biggest single causes ofchronic illness in the world today. Known in the United States asChronic Fatigue Syndrome and in Great Britain both as MyalgicEncephalomyelitis and Post-Viral Fatigue Syndrome, M.E./CFS hasprovoked a chronic disabling illness in an estimated 1,000,000 personsin North America and Europe.

This book provides, in one superb 75-chapter source, an up-to-date,comprehensive account of current knowledge concerning the history,epidemiology, children with M.E., investigation, virology, immunology,muscle pathology, host response, food intolerance, brain mapping,neurophysiology, neuropsychology, psychiatry, sleep dysfunction,fibromyalgia syndrome, treatment and management.

This is an essential reference book for medical, government and publiclibrary reference rooms. This text is a unique vehicle forresearchers, physicians and other health education and governmentofficials, and is easily understandable by the general publicinterested in M.E./CFS.

All funds from this text will be used both to promote research and toassist in greater understanding of M.E./CFS. ... Read more

Customer Reviews (6)

The Clinical and Scientific Basis of Myalgic Encephalmyelitis -- Chronic Fatigue Syndrome
This book was an extensive compilation of the clinical work and research efforts of a great number of qualilfied medical doctors, from not only America but from around the world as well. From one who has suffered the effects of ME/CFS for a number of years...with time out for good behavior..I was dumbfounded that so much work and intense effort has been put in to the study and depth that was shown in this work.
It is very readable and well organized.The extensive index also helped with the specific information in question.I recommend it for medical personnel so that the patients who complain of ME/CFS will have a chance to make headway under your watch.

This book will help to take us out of the dark ages of marginalizing the ME/CFS sufferers and in to the realm of considering their needs and motivating adequate
care and healing modes.

Excellent information from Dr. Byron Hyde
The information by Dr. Hyde in this book is essential to understanding what ME is.He has an excellent track record in the area of ME research, can't recommend his writings enough!

A vital resource for patients and doctors!
When you or someone you love is suddenly stricken with a serious illness, you want an experienced, knowledgeable doctor to be able to diagnose and treat you efficiently and with sympathy.Unfortunately this isn't always possible, and victims of poorly understood illness often have to fight for recognition and appropriate treatment.The only way to avoid getting lost in the healthcare system or, even worse, to find yourself participating in prescribed treatment programs that may do more harm than good, is to arm yourself with as much knowledge as you can.

The Nightingale Foundation is one of the few bodies dedicated to researching M.E. and disseminating useful information about the disease.It is also one of the few organisations to advocate the distinction between Myalgic Encephalomyelitis and what is commonly called Chronic Fatigue Syndrome - a crucial qualification."The Clinical and Scientific Basis of Myalgic Encephalomyelitis--Chronic Fatigue Syndrome" is an unparalleled resource for patients and clinicians trying to understand this baffling illness.The Nightingale Foundation's ground-breaking definition of M.E. was drafted to quickly diagnose and effectively treat M.E. and also to "give comfort to M.E. patients everywhere."It seems like a large, intimidating reference book, but I can personally vouch for the comfort its been to me throughout my illness.Tested scientific facts are more reassuring than anything when you're ill and feel like you've been abandoned by the medical profession.

An essential M.E. textbook for patient and doctor alike
An excellent resource from Dr Byron Hyde MD (editor).

This book is the one and only M.E. textbook. This book is essential reading for anyone with M.E., or an interest in M.E. Buy this book!!!

Not all of the many chapters in this book are worthwhile or still current, BUT this book is well worth the price and the 5 stars even if only for the five or six chapters written by Dr Hyde, unarguably the world's leading M.E. expert.

I'd also highly recommend you check out Dr Hyde's more recent writings. I cannot recommend them highly enough.

The clinical and scientific basis of Myalgic Encephalitis
Unbelievably insightfull to those who have or are suffering
from this devestating disease process .Every treating physician
should have this in there office.In my personal observations
with some people I have met and also myself and my wife it is
definetly and as a matter of medical fact a potential lifesaver.
The fact that this author Dr. Byron Hyde has went to extreme
lenghts to study research and organise the world symposium
on this to gather varied medical research and facts from all

these brilliant minds tells me that this man deserves at the
very least a medal of Honour but rather the Nobel Peace Prize
for devoting at least 25 years of his life to studying and
caring enough to try and find the cause and cure of so much
human suffering that exists in our world. My sincerest regards...
P.S. I passed on the book to another fellow sufferer and never
really got the chance to read very much but my doctor has one now. ... Read more

Product Description
This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to acute disseminated encephalomyelitis (also disseminated encephalomyelitis), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on acute disseminated encephalomyelitis. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms. ... Read more

Product Description
The Calgary Women's Emergency Shelter, Canada. An examination of the testimonials of four teenage sufferers of chronic fatigue syndrome, offering a survival guide for patients and parents and insight for health care professionals. Hardcover, softcover also available. ... Read more

Product Description
Webster's bibliographic and event-based timelines are comprehensive in scope, covering virtually all topics, geographic locations and people. They do so from a linguistic point of view, and in the case of this book, the focus is on "Encephalomyelitis," including when used in literature (e.g. all authors that might have Encephalomyelitis in their name). As such, this book represents the largest compilation of timeline events associated with Encephalomyelitis when it is used in proper noun form. Webster's timelines cover bibliographic citations, patented inventions, as well as non-conventional and alternative meanings which capture ambiguities in usage. These furthermore cover all parts of speech (possessive, institutional usage, geographic usage) and contexts, including pop culture, the arts, social sciences (linguistics, history, geography, economics, sociology, political science), business, computer science, literature, law, medicine, psychology, mathematics, chemistry, physics, biology and other physical sciences. This "data dump" results in a comprehensive set of entries for a bibliographic and/or event-based timeline on the proper name Encephalomyelitis, since editorial decisions to include or exclude events is purely a linguistic process. The resulting entries are used under license or with permission, used under "fair use" conditions, used in agreement with the original authors, or are in the public domain. ... Read more

Customer Reviews (1)

Exposes the War on Science
Details the very underreported war on science by a small cadre of British psychiatrists.Simon Wessely has made a cottage industry of kicking the disabled when they're down including military veterans. Nicely exposes this emperor of charlatans' complete lack of clothes.Also see Prof. Malcolm Hooper's excellent works, posted free on the internet. ... Read more

Product Description
An explanation of the clinical nature of M.E. describing the virological and other tests and answering the basic questions which sufferers and doctors unacquainted with the disease will ask. The book also describes conventional and alternative treatments and gives views on their efficacy. ... Read more

Product Description
Covers varied organ pathology in a wide range of syndromes induced by viral infection and toxin exposure. Discusses such lethal problems as cardiomyopathy, liver failure, pancreatic cancer, brain tumors, and renal disease. Includes photographs, photomicrographs, charts, EKGs, X rays, and graphic depictions of other medical test results. Hardcover, softcover available. ... Read more

Product Description
An important medical milestone for anyone connected with ME/CFS!

Myalgic Encephalomyelitis / Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols includes a clinical definition (clinical diagnostic criteria) for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The clinical case definition was developed by an expert medical consensus panel of treating physicians, teaching faculty and world leaders in the research of ME/CFS. An expert subcommittee of Health Canada established the Terms of Reference for the consensus panel. The definition more adequately reflects the complexity of symptoms of a given patient’s pathogenesis and should establish ME/CFS as a distinct medical entity and help distinguish it from overlapping medical conditions in the absence of a definitive laboratory test.

“The clinical definition will enable clinicians to make an early diagnosis which may assist in lessening the impact of ME/CFS in some patients,” said Dr. Bruce M. Carruthers, lead author of the definition. “It will reduce the expensive problem of patients being sent to many specialists before being diagnosed and will allow patients to receive appropriate treatments in a timely fashion.”

The panel's clinical case definition determines that more of the prominent symptoms are compulsory and symptoms that share a common region of pathogenesis are grouped together for clarity. In addition to severe prolonged fatigue, the definition includes the hallmark symptoms of post-exertional malaise and/or fatigue, sleep dysfunction, pain, two or more of the given neurological/cognitive manifestations, and at least one of the given symptoms from two of the categories of autonomic, neuroendocrine, and immune manifestations. Diagnostic exclusions and common co-morbid entities are also given.

The special issue of the Journal of Chronic Fatigue Syndrome also includes a discussion of prominent symptoms, clinical practice diagnostic and treatment guidelines based on the best available research evidence, and an overview of available research on ME/CFS.

The expert panel of 11 physicians—who have diagnosed and/or treated more than 20,000 ME/CFS patients between them—has developed a clinical case definition that provides a flexible conceptual framework based on the characteristic patterns of symptom clusters, which reflect specific areas of pathogenesis. The expert subcommittee of Health Canada selected the expert consensus panel.

Authors include:

• Dr. Bruce M. Carruthers, lead author of the consensus document; co-author of the draft of the original version of the ME/CFS clinical definition, diagnostic and treatment protocols document; internal medicine, Galiano, British Columbia.
• Dr. Anil Kumar Jain, co-author of the draft the original version of the ME/CFS consensus document, affiliate of Ottawa Hospital, Ontario.
• Dr. Kenny L. De Meirleir, Professor Physiology and Medicine, Vrije Universiteit Brussel, Brussels, Belgium; ME/CFS researcher and clinician; organizer of the World Congress on Chronic Fatigue Syndrome and Related Disorders; a board member of the American Association for Chronic Fatigue Syndrome; and co-editor of Chronic Fatigue Syndrome: Critical Reviews and Clinical Advances (Haworth)
• Dr. Daniel L. Peterson, affiliate of the Sierra Internal Medicine Associates in Incline Village, Nevada; ME/CFS researcher and clinician; a board member of the American Association for Chronic Fatigue Syndrome; and member of the International Chronic Fatigue Syndrome Study Group
• Dr. Nancy G. Klimas, Clinical Professor of Medicine in Microbiology/Immunology/Allergy and Psychology, University of Miami School of Medicine; ME/CFS researcher and clinician; a board member of the American Association for Chronic Fatigue Syndrome; and member of the federal CFS Coordinating Committee
• Dr. A. Martin Lerner, staff physician at William Beaumont Hospital in Royal Oak, Michigan; Clinical professor and former chief of the Division of Infectious Diseases at Wayne State University's School of Medicine; and ME/CFS researcher and clinician
• Dr. Alison C. Bested, haematological pathologist; former head of the Division of Haematology and Immunology at the Toronto East General and Orthopaedic Hospital; affiliate of the Environmental Health Clinic and Sunnybrook & Women's College Health Sciences Centre, Toronto, Ontario; ME/CFS researcher and clinician
• Dr. Pierre Flor-Henry, Clinical Professor of Psychiatry, University of Alberta; Clinical Director of General Psychiatry and Director of the Clinical Diagnostic and Research Centre, both based at Alberta Hospital in Edmonton, Alberta, Canada; ME/CFS brain researcher
• Dr. Pradip Joshi, internal medicine, Clinical Associate Professor of Medicine at Memorial University of Newfoundland in St. John's, Canada
• Dr. A. C. Peter Powles, Professor Emeritus, Faculty of Health Science, McMasters University, Hamilton; Professor, Faculty of Medicine, University of Toronto; Chief of Medicine and Sleep Disorders Consultant, St. Joseph's Health Centre, Toronto; Sleep Disorder Consultant at the Sleep Disorder Clinic at St. Joseph's Healthcare, Hamilton, and Central West Sleep Affiliation, Paris, Ontario
• Dr. Jeffrey A. Sherkey, family medicine, affiliate of the University Health Network, Toronto, Ontario; and diagnosed with chronic fatigue syndrome nearly 10 years ago
• Marjorie I. van de Sande, Consensus Coordinator; and Director of Education for the National ME/FM Action Network, Canada

Customer Reviews (2)

The Definitive Document on ME/CFIDS
This is the most authoritative Definition and Treatment Guidelines by far for ME/CFIDS.Explains with piercing clarity this common and extremely disabling neuro-endocrine immune disease.

Clinical definition of an organic brain disease
This edition contains the full 2003 Canadian clinical definition for this ICD-10 G93.3 brain disease developed by the biomedical researchers and clinicians who have seen and treated the organic symptoms of thousands of patients accurately diagnosed with this disease. Post exertional exhaustion unrelieved by rest (not tiredness) is but one symptom of many signs and symptoms required to diagnose this complex disease. Medically relevant signs (objective ways doctors use to test symptoms)are noted. A good book to help your physician understand this organic disease. Ask your local library to purchase it. Remember what all good clinicians know: A syndrome may contain a symptom, but a symptom is never a syndrome. ... Read more

Product Description
The pathology of multiple sclerosis and EAE hasshown converging evidence of the oxidative stresscausing perivascular mononuclear infiltrate causingdemyelination. The phase 2 enzymes are known todecrease the oxidative stress. We used 24 Lewisrats, placed in two groups: 1) non-BHA (normalchow), 2) BHA soaked chow)to test this fact in EAE.All the animals were administered 100 µg of guineapig myelin basic protein in their tails to induceEAE and examined daily in a double blinded fashion.On 29th day of the induction the animals weresacrificed, blood collected for glutathione (GSH)measurements and tissues collected for histology.All the animals, regardless of their diet status,developed symptoms of EAE and reached remission ofacute EAE before 28th day of induction. Thehistology of the non-BHA group correlated well withthe clinical symptoms of perivascular mononuclearinfiltration. However the BHA group revealedcomplete pathological recovery. The BHA rats alsohad significantly raised GSH indicating theinduction of phase 2 enzymes. We conclude thatdietary phase 2 enzyme inducers show potentialtherapeutic benefits in EAE. ... Read more

Product Description

Targeted to patients, their families and allied health students, The “Gale Encyclopedia of Neurological Disorders” provides in-depth coverage of neurological diseases and disorders, including stroke, multiple sclerosis, Parkinson disease, Tourette Syndrome, Alzheimer's disease, cerebral palsy, vertigo, amnesia and epilepsy. Related topics include communication aids, electric personal assistive mobility devices, medications for treating neurological diseases and conditions, understanding the needs of Alzheimer patient caregivers and more. This two-volume set provides an alternative to resources that either fail to explore neurological disease in any depth and or do so at a level not appropriate for students and general readers.