Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

Product Description
Familial hypercholesterolemia (abbreviated FH, also spelled familial hypercholesterolaemia) is a genetic disorder characterized by high cholesterol levels, specifically very high low-density lipoprotein (LDL, "bad cholesterol") levels, in the blood and early cardiovascular disease. Many patients have mutations in the LDLR gene that encodes the LDL receptor protein, which normally removes LDL from the circulation, or apolipoprotein B (ApoB), which is the part of LDL that binds with the receptor; mutations in other genes are rare. Patients who have one abnormal copy (are heterozygous) of the LDLR gene may have premature cardiovascular disease at the age of 30 to 40. Having two abnormal copies (being homozygous) may cause severe cardiovascular disease in childhood. Heterozygous FH is a common genetic disorder, occurring in 1:500 people in most countries; homozygous FH is much rarer, occurring in 1 in a million births. Heterozygous FH is normally treated with statins, bile acid sequestrants or other hypolipidemic agents that lower cholesterol levels. ... Read more

Product Description
This digital document is an article from Family Practice News, published by International Medical News Group on February 1, 2004. The length of the article is 635 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Statin reverses atherogenesis in highest-risk kids familial hypercholesterolemia.(Children's Health)
Author: Bruce Jancin
Publication: Family Practice News (Magazine/Journal)
Date: February 1, 2004
Publisher: International Medical News Group
Volume: 34Issue: 3Page: 96(1)

Distributed by Thomson Gale ... Read more

Product Description
This digital document is an article from MedSurg Nursing, published by Jannetti Publications, Inc. on August 1, 2004. The length of the article is 3117 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: Familial hypercholesterolemia is one of the most frequent genetic disorders. The increased cholesterol levels in the plasma low-density lipoprotein fraction due to the diminished number or absence of LDL receptors predispose affected individuals to premature atherosclerosis and cardiovascular disease.

Citation Details
Title: Familial hypercholesterolemia: genetic predisposition to atherosclerosis.(Advanced Practice)
Author: Mary B. Engler
Publication: MedSurg Nursing (Refereed)
Date: August 1, 2004
Publisher: Jannetti Publications, Inc.
Volume: 13Issue: 4Page: 253(5)

Distributed by Thomson Gale ... Read more

Product Description
This digital document is an article from Pediatric News, published by International Medical News Group on February 1, 2004. The length of the article is 515 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Statin reverses atherogenesis in highest-risk children: familial hypercholesterolemia.
Author: Bruce Jancin
Publication: Pediatric News (Magazine/Journal)
Date: February 1, 2004
Publisher: International Medical News Group
Volume: 38Issue: 2Page: 2(1)

Distributed by Thomson Gale ... Read more

Product Description
Chapters: Low-Density Lipoprotein, Cholesterol, High-Density Lipoprotein, Triglyceride, Familial Hypercholesterolemia, Lipoprotein(a), Mevalonate Inhibition, Cholesterol Depletion, Hypertriglyceridemia, Hyperlipidemia, Hypocholesterolemia, Combined Hyperlipidemia, Lipoprotein Lipase Deficiency. Source: Wikipedia. Pages: 115. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: 148150 °C Microscopic appearance of cholesterol crystals in water. Photo taken under polarized light.Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma of all animals. It is an essential structural component of mammalian cell membranes, where it is required to establish proper membrane permeability and fluidity. In addition, cholesterol is an important component for the manufacture of bile acids, steroid hormones, and fat-soluble vitamins including Vitamin A, Vitamin D, Vitamin E, and Vitamin K. Cholesterol is the principal sterol synthesized by animals, but small quantities are synthesized in other eukaryotes, such as plants and fungi. It is almost completely absent among prokaryotes, which include bacteria. Although cholesterol is an important and necessary molecule for animals, a high level of serum cholesterol is an indicator for diseases such as heart disease. The name cholesterol originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as François Poulletier de la Salle first identified cholesterol in solid form in gallstones, in 1769. However, it was only in 1815 that chemist Eugène Chevreul named the compound "cholesterine". Since cholesterol is essential for all animal life, it is primarily synthesized from simpler substances within the body. However, high levels in blood circulation, depending on how it is transpo...More: http://booksllc.net/?id=6437 ... Read more

Product Description
This digital document is an article from Human Biology, published by Thomson Gale on October 1, 2005. The length of the article is 4221 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: KEY WORDS: FAMILIAL DEFECTIVE APOB, AUTOSOMAL DOMINANT MONOGENIC HYPERCHOLESTEROLEMIA (ADMH), HYPERCHOLESTEROLEMIA, APOB, LDLR, R3500Q MUTATION, T3552T MUTATION, SSCP (SINGLE-STRAND CONFORMATION POLYMORPHISM) ANALYSIS, SPAIN.

Citation Details
Title: Screening of APOB gene mutations in subjects with clinical diagnosis of familial hypercholesterolemia.
Author: Erardo Merino-Ibarra
Publication: Human Biology (Magazine/Journal)
Date: October 1, 2005
Publisher: Thomson Gale
Volume: 77Issue: 5Page: 663(11)

Distributed by Thomson Gale ... Read more