Product Description

Inflammation in gastrointestinal mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it has fundamental clinical consequences, the principal of which is premalignant metaplasia throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for GI cancer.

This book discusses all aspects of the relation between inflammation and GI cancer, from the basic science through to the translational science which is helping in the optimization of clinical management strategies. Among the topics considered are the impact of inherited syndromes; the roles of acid reflux, H. pylori, inflammatory bowel disease, and primary sclerosing cholangitis; screening strategies; targeted drug therapies; genetics; and the use of endoscopic methods. The authors are the best in their field, and this book is designed for the enthusiastic student as well as the professional in GI science and medicine.

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This digital document is an article from Southern Medical Journal, published by Southern Medical Association on August 1, 2002. The length of the article is 2425 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Metastatic breast cancer manifested as refractory anemia and gastric polyps.
Author: Tara B. Karamlou
Publication: Southern Medical Journal (Refereed)
Date: August 1, 2002
Publisher: Southern Medical Association
Volume: 95Issue: 8Page: 922(4)

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Product Description
This report of a workshop examines the mechanisms by which tumours of the forestomach and tumours of gastric neuroendocrine cell origin occur in rodents, and considers the predictive value of these tumours for the identification of carcinogenic hazards to humans. Etiological risk factors in rodents are summarized and evidence for the possible carcinogenic mechanisms involved is discussed.Recommendations are presented on how mechanistic data could be used in overall evaluations of carcinogenicity to humans. Summary reports at the beginning of each section use the background scientific reviews and case studies that were prepared before the workshop by individual participants. These individually authored papers formed the basis for the discussions that were held and are also included in this report. ... Read more