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Univ. of Munster, Germany. Presents the rapid progress in the medical understanding of leukemia and the identification of novel therapeutic approaches for the disease. Coverage includes first-hand reports from leading study groups and the latest updates on multicenter trials of new therapies. DNLM: Leukemia--Therapy. ... Read more

Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient.

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This is the fifth volume in a series on methods of treating acute leukemia. Chemo-resistance is discussed, along with the preclinical evaluation of candidate drugs, the biology and clinical trials in resistant and relapsed disease, and the bone marrow and blood stem cell transplantation. There are also comprehensive sections dealing with growth factors, induction of differentiation immunotherapy and gene therapy. The book thus provides the clinician with guidelines for the use in everyday's practice. ... Read more

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New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology.

Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided.A number of experimental drug reagents currently in clinical investigation are also discussed.The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers.

The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future.

* Provides an up-to-date, state of the art discussion of a rapidly changing field
* Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells
* Written by international experts in each of the fields ... Read more

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Hopital Necker, Paris, France.Third in this CD-ROM series. Illus trates the leukemias peripheral blood and bone marrow cytological pattern. Contains between 1000 and 2000 high resolution images with data sheets based on leading international encoding systems, such as SNOMED, ICD 10, etc. System requirements: Pentium PC, Windows 95, 16Mb RAM. ... Read more

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This monograph, written by one of the world's leading cytogeneticists in the field of hematology, decribes the large number of chromosome changes that have now been implicated in acute lymphoblastic leukemia (ALL). Both the well established method of banding and the newer fluorescence in-situ hybridisation, Southern blotting and polymerase chain reaction techniques are reviewed. A glossary of terms used in this field, essential for all non-chromosomal cogniscenti, is included. The most important translocations, partial deletions and chromosome gains and losses are illustrated and the clinical and molecular significance of each is described. ... Read more

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This book reports on the VIIIth Wilsede Meeting on Modern Trends in Human Leukemia held in June 1988. The contributions are divided into clinical, immunological, cell biological, virological and molecular genetic sections. The Wilsede Joint Meeting on Pediatric Oncology V is also included. The Frederick Stohlmann Lectures were given by Janet Rowley and Malcolm Moore, while C. Gajdusek gave a very special lecture on the fantasy of a virus from the inorganic world. Bone marrow transplantation, using haemopoetic growth factors and the diagnostic value of molecular genetics were discussed. The VIIIth Wilsede Meeting shows again that the new technologies achieved do not eliminate the old ones. This was discussed by Alexander Friedenstein shown in the results Alexander Maximov achieved in 1907. The book demonstrates the complexity of leukemia research as a tool for human biology. The book will be of value to both clinicians and researchers in many fields of oncology, as well as for investigators and students interested in human biology. Of further interest: R. Neth, R.C. Gallo, M.F. Greaves, Modern Trends in Human Leukemia - Vol. VI. 1985. ISBN 3-540-15329-2 - Vol. VII. 1987. ISBN 3-540-17754-X ... Read more

Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more