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This digital document is an article from Environmental Health Perspectives, published by Thomson Gale on June 1, 2006. The length of the article is 6579 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Incidence of leukemia, lymphoma, and multiple myeloma in Czech uranium miners: a case-cohort study.(Research)
Author: Vladimir Rericha
Publication: Environmental Health Perspectives (Magazine/Journal)
Date: June 1, 2006
Publisher: Thomson Gale
Volume: 114Issue: 6Page: 818(5)

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This digital document is an article from Ear, Nose and Throat Journal, published by Thomson Gale on September 1, 2007. The length of the article is 2667 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Recurrence of isolated multiple myeloma in the skull base: a case report and review of the literature.(ORIGINAL ARTICLE)(Clinical report)
Author: Omar F. Husein
Publication: Ear, Nose and Throat Journal (Magazine/Journal)
Date: September 1, 2007
Publisher: Thomson Gale
Volume: 86Issue: 9Page: 555(6)

Article Type: Clinical report

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This digital document is an article from Southern Medical Journal, published by Thomson Gale on November 1, 2006. The length of the article is 1168 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Giant cell arteritis mimicking multiple myeloma; diagnosed by PET scan.(positron emission tomography)
Author: Satheesh K. Kathula
Publication: Southern Medical Journal (Magazine/Journal)
Date: November 1, 2006
Publisher: Thomson Gale
Volume: 99Issue: 11Page: 1280(2)

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The t(4;14) translocation, present in ca. 20% ofcases of Multiple Myeloma, results in the dysregulation of twopotential oncogenes, MMSET and FGFR3, via juxtaposition to regulatoryelements of the IgH locus. The presence of t(4;14) and overexpression oftranscripts from the MMSET locus are adverse prognostic factors inMultiple Myeloma irrespective of FGFR3 expression, implicating MMSETin disease pathogenesis. MMSET is a biologically activetranscriptional effector that could mediate a series of repressive changes byacting as a methyltransferase enzyme in chromatin remodeling andas a complex adaptor in the recruitment of repressor species. ... Read more

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This digital document is an article from Internal Medicine News, published by Thomson Gale on March 15, 2007. The length of the article is 718 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Multiple myeloma responds to new regimens.(Hematology)
Author: Bruce Wilson
Publication: Internal Medicine News (Magazine/Journal)
Date: March 15, 2007
Publisher: Thomson Gale
Volume: 40Issue: 6Page: 19(1)

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This digital document is an article from Family Practice News, published by Thomson Gale on March 1, 2007. The length of the article is 483 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: CT ideal for monitoring multiple myeloma patients.(Clinical Rounds)
Author: Bruce K. Dixon
Publication: Family Practice News (Magazine/Journal)
Date: March 1, 2007
Publisher: Thomson Gale
Volume: 37Issue: 5Page: 53(1)

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The article is excerpted fromGale Encyclopedia of Cancer
The resource students and researchers will turn to for reliable, up-to-date and clearly written information, the Gale Encyclopedia of Cancer is a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures. The Encyclopediaincludes entries covering cancers, cancer drugs, treatments, sideeffects and diagnostic procedures. Entries typically include thefollowing elements:

• Causes and Symptoms
• Definition
• Description
• Diagnosis
• Prevention
• Resources
• Risks
• Special Concerns
• And more

An appendix provides complete contact information for cancercenters, national support groups, government agencies and researchgroups. Features include anatomical illustrations of the major bodysystems, a subject index and approximately 200 photographs and drawings. ... Read more

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This digital document is an article from Internal Medicine News, published by Thomson Gale on March 15, 2007. The length of the article is 482 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Low-dose CT recommended to detect multiple myeloma.(Hematology)
Author: Bruce K. Dixon
Publication: Internal Medicine News (Magazine/Journal)
Date: March 15, 2007
Publisher: Thomson Gale
Volume: 40Issue: 6Page: 18(1)

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This digital document is an article from Skin & Allergy News, published by International Medical News Group on September 1, 2002. The length of the article is 545 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Thalidomide is promising for HIV-related cancers. (Multiple Myeloma).
Author: Mary Ann Moon
Publication: Skin & Allergy News (Magazine/Journal)
Date: September 1, 2002
Publisher: International Medical News Group
Volume: 33Issue: 9Page: 29(1)

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This digital document is an article from Gale Encyclopedia of Medicine, 3rd ed., brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 2407 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.The third edition of this authoritative, comprehensive, in-depth medical guide features information on medical topics in language accessible to adult laypersons. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. ... Read more

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Chapters: Sam Walton, Roy Scheider, Bernard Williams, V. P. Singh, Peter Boyle, Hulda Regehr Clark, Ralph Ginzburg, Stan Winston, Yvon Cormier, Ali Kordan, Louis Rukeyser, Ralph D. Winter, Mickey Hargitay, Warren William, Moe Drabowsky, Angela Coughlan, J. Carter Brown, Carla Moran, Anna Held, Don Herbert, Michel Mirowski, Tom Cole, Eppie Lederer, Derek Denny-Brown, Caro Jones, Lloyd Thaxton, Phil Smith, Nathan Isgur, Cyril Walsh, Merle Sande, Jim Davis, Richard Bell, Martha Beall Mitchell, Jo Clayton, Daniel Seligman, Ted Uhlaender, Jacob A. Marinsky, Robert Rosenthal, Leo Edward O'neil, Thomas William Ferguson, Mark Lenard, Hayden Rorke, Scott M. Matheson, Michael Vernon, Rena Kanokogi, Vern Ruhle, Terry Zahn, Jack Rosenthal, Grace Abbott, Gilbert Moses, George Andreasen, Ras Shorty I, Stephen J. Friedman, Kazue Takahashi, Caroline Mcwilliams, Grace Halsell, Mario Acuña, Bülent Arel, Abolfazl Monadi, Graham Jarvis, Malcolm Diamond, John Sack, Harry Goz, B. J. Kennedy, Warren Spears. Source: Wikipedia. Pages: 284. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Sir Bernard Arthur Owen Williams (21 September 192910 June 2003) was an English moral philosopher, described by The Times as the "most brilliant and most important British moral philosopher of his time". His publications include Problems of the Self (1973), Moral Luck (1981), Ethics and the Limits of Philosophy (1985), and Truth And Truthfulness: An Essay In Genealogy (2002). As Knightbridge Professor of Philosophy at the University of Cambridge and Deutsch Professor of Philosophy at the University of California, Berkeley, Williams became known internationally for his attempt to reorient the study of moral philosophy to history and culture, politics and psychology, and, in particular, to the Greeks. Described as an "analytic philos...More: http://booksllc.net/?id=552586 ... Read more

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This digital document is a journal article from DNA Repair, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Multiple myeloma (MM) is a malignant post-germinal center tumor of somatically-mutated, isotype-switched plasma cells that accumulate in the bone marrow. It often is preceded by a stable pre-malignant tumor called monoclonal gammopathy of undetermined significance (MGUS), which can sporadically progress to MM. Five recurrent primary translocations involving the immunoglobulin heavy chain (IgH) locus on chromosome 14q32 have been identified in MGUS and MM tumors. The five partner loci include 11q13, 6p21, 4p16, 16q23, and 20q12, with corresponding dysregulation of CYCLIN D1, CYCLIN D3, FGFR3/MMSET, c-MAF, and MAFB, respectively, by strong enhancers in the IgH locus. The five recurrent translocations, which are present in 40% of MM tumors, typically are simple reciprocal translocations, mostly having breakpoints within or near IgH switch regions but sometimes within or near VDJ or JH sequences. It is thought that these translocations are caused by aberrant IgH switch recombination, and possibly by aberrant somatic hypermutation in germinal center B cells, thus providing an early and perhaps initiating event in transformation. A MYC gene is dysregulated by complex translocations and insertions as a very late event during the progression of MM tumors. Since the IgH switch recombination and somatic hypermutation mechanism are turned off in plasma cells and plasma cell tumors, the MYC rearrangements are thought to be mediated by unknown mechanisms that contribute to structural genomic instability in all kinds of tumors. These rearrangements, which often but not always juxtapose MYC near one of the strong immunoglobulin enhancers, provide a paradigm for secondary translocations. It is hypothesized that secondary translocations not involving a MYC gene can occur at any stage of tumorigenesis, including in pre-malignant MGUS tumor cells. ... Read more

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This digital document is an article from Southern Medical Journal, published by Southern Medical Association on October 1, 2004. The length of the article is 337 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Unusual and extremely rare presentation of multiple myeloma with extra-medullary plasmacytomas: a case report.(Section on Oncology)
Author: Ganesh D. Kini
Publication: Southern Medical Journal (Refereed)
Date: October 1, 2004
Publisher: Southern Medical Association
Volume: 97Issue: 10Page: S28(1)

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This digital document is an article from Transplant News, published by Thomson Gale on August 1, 2007. The length of the article is 494 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

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Title: Genzyme says phase 3 Mozobil trials meet primary endpoints for treating non-Hodgkin's lymphoma, multiple myeloma.
Author: Gale Reference Team
Publication: Transplant News (Newsletter)
Date: August 1, 2007
Publisher: Thomson Gale
Volume: 17Issue: 8

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This digital document is an article from Transplant News, published by Transplant Communications, Inc. on February 16, 2004. The length of the article is 398 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Double stem cell transplant after HDC improves survival in multiple myeloma patients.
Publication: Transplant News (Newsletter)
Date: February 16, 2004
Publisher: Transplant Communications, Inc.
Volume: 14Issue: 3

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This digital document is an article from Southern Medical Journal, published by Southern Medical Association on February 1, 2005. The length of the article is 1639 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Hepatic plasmacytosis as a manifestation of relapse in multiple myeloma treated with thalidomide.(Case Report)
Author: Auro del Giglio
Publication: Southern Medical Journal (Refereed)
Date: February 1, 2005
Publisher: Southern Medical Association
Volume: 98Issue: 2Page: 238(3)

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