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MDS is a lethal blood disease that affects as many as 50 per 100,000 individuals over the age of 70. The disorder is five times more prevalent than AML, a form of leukemia. Whether you're a newly diagnosed patient, a survivor, or loved one of someone suffering from MDS, this book offers help. The only text available to provide both the doctor's and patient's views, 100 Questions & Answers About Myelodysplastic Syndromes, provides practical, authoritative answers to 100 of the most common questions asked. Written with commentary from actual patients, this is an invaluable resource for anyone struggling with the medical, physical, and emotional turmoil of this disease. ... Read more

Customer Reviews (1)

Very informative and easy to understand
Breaking down the book into questions and answers is a great way to understand more about the disease. I found it very informative. ... Read more

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This up-to-date and comprehensive set of two CD-ROM discs provides a superb collection of official Federal government documents on myelodysplastic syndromes: signs and symptoms, diagnosis, lab tests, treatment and management options, and ongoing clinical research. Every aspect of the disease is thoroughly covered. Myelodysplastic syndromes are a group of diseases in which the bone marrow does not make enough healthy blood cells. Also called preleukemia and smoldering leukemia.For patients, practical information is provided in clearly written patient education documents. For medical professionals, doctor references and texts have detailed technical information and clinical background material. Documents from the National Cancer Institute, Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), National Institutes of Health (NIH), Environmental Protection Agency (EPA), Medline, Centers for Medicare and Medicaid Services (CMS), and Occupational Health and Safety Administration (OSHA) are included. In addition to disease-specific information, there is extensive coverage of the broad subject of cancer and its prevention and treatment (surgery, chemotherapy, radiation, advanced treatments, managing side effects). There is no other reference that is as fast, convenient, and portable - everything you need to know, from the federal sources you trust.Since navigating the Internet to find medical information can be confusing, our exclusive "Guide to Leading Medical Websites 2009" has updated links to the 67 best sites! Weblinks let you quickly check for the latest clinical updates directly from the government and the best commercial portals, news sites, reference/textbook/non-commercial portals, and health organizations.Comprehensive cancer coverage includes: FDA Office of Oncology Drug Products, Oncology Tools - approved drugs, patient liaison * Dictionary of Cancer Terms (4000 items) * Division of Cancer Biology * Cancer Bulletin - archive of informative articles from NCI publication since 2004 * Cancers by Body Location, System * A-Z list of cancers * Clinical Trials * Complementary and Alternative Medicine * Coping - Complications and Side Effects - fatigue, pain, cardiopulmonary syndromes, cognitive disorders and delirium; fever, sweats, hot flashes; gastrointestinal complications, hypercalcemia; lymphedema; pruritus; sexuality and reproduction; sleep; nutrition; eating hints; emotions, anxiety, depression, adjustment, post-traumatic stress disorder; substance abuse; transitional care planning; radiation, home care, when cancer returns; Care for the Caregiver; Survivorship - end of life issues, advance directives, coping with advanced cancer, Hospice, Loss, Grief, and Bereavement * Division of Cancer Treatment and Diagnosis * Drug Development and Approval * Approved Oncology Drugs * Drug Dictionary - technical definitions and synonyms * Drug Information Summaries * Factsheets by cancer type, risk factors and possible causes, prevention, detection, diagnosis, therapy, support, coping, resources, tobacco and smoking cessation * Prevention, Genetics * Publications - specific cancers, treatment, trials, coping, testing, risks, nutrition * Screening and Testing * Support - organizations, finances and insurance * Chemotherapy, Radiation Therapy, Surgery, Cryosurgery, Laser, Hyperthermia, Targeted * Understanding Cancer - sixty-one publications * CDC Division of Cancer Prevention and Control * SEER Surveillance Epidemiology and End Results * Cancer Health Disparities * Cancer Centers Program. ... Read more

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The MediFocus Guidebook on Myelodysplastic Syndromes is the most comprehensive, up-to-date source of information available. You will get answers to your questions, including risk factors of Myelodysplastic Syndromes, standard and alternative treatment options, leading doctors, hospitals and medical centers that specialize in Myelodysplastic Syndromes, results of the latest clinical trials, support groups and additional resources, and promising new treatments on the horizon. This one of a kind Guidebook offers answers to your critical health questions including the latest treatments, clinical trials, and expert research; high quality, professional level information you can trust and understand culled from the latest peer-reviewed journals; and a unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks. This Guidebook was updated on March 25, 2010. ... Read more

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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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This book describes the clinical classification, underlying biological mechanisms and treatment of the myelodysplastic syndromes. Authored by international experts, the chapters cover all aspects of the myelodysplastic syndromes, from an in-depth analysis of the multifactorial nature of this disease, including an assessment of stromal, immunological and stem cell abnormalities, to a review of recent molecular and cytogenetic discoveries and insights. This book will be a valuable resource to clinicians and researchers who wish to learn more about myelodysplastic syndromes. ... Read more

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Written by a team of leading authorities in pathogenesis, diagnostic techniques, and clinical management strategies in myelodysplastic syndrome (MDS), this text provides a concise, easy-to-follow review of the advances in the science, classification, diagnosis, and management of the condition.

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Myelodysplastic syndromes are to the bone marrow what pneumoniais to the lungs; the response of an organ to a variety of etiologicinsults like aging, toxic exposure, infections and auto-immunity.Among infectious causes alone, pneumonia could be the result of avariety of possible pathogens including bacterial, viral, tuberculousor fungal agents. Similarly, MDS cannot be treated as a singledisease. Attempts to harness the inherent complexity of MDS bydevising `classifications' which group the various syndromes as onedisease is as misguided as saying that a pneumonia is not infectiousbecause it did not respond to antibiotics. Progress in the field willoccur faster when we re-analyze this premise. Therefore, until aclearer picture of the disease emerges it is best to treat each of theMDS syndromes as a separate entity. Having no classification is betterthan a misleading one.

Cancer research has been notable for its periodic cycles of promiseand hope, followed by defeat and disappointments. It is not that thereis no solution, but that the problem has not been identifiedprecisely. This book is our attempt to define the most crucialquestions related to MDS that need to be addressed immediately throughlogic, analysis and rigorous experimentation. If the emerging problemsappear daunting, then instead of being overwhelmed by them, we shouldfollow the advice of the great 20th century thinker Antonio Gramsci,`pessimism of the intellect must be faced with the optimism of will'. ... Read more

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This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to myelodysplastic syndromes (also Chronic myelomonocytic anemia; Dysmyelopoietic syndrome; Hemopoietic dysplasia; Preleukemia; Smoldering or subacute myeloid leukemia), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on myelodysplastic syndromes. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms. ... Read more

Customer Reviews (1)

The Copyright date on this Book is November 2002

Medical treatment of Myelodysplplastic Syndromes is an area undergoing rapid change, so a gap of eight years is significant.

Otherwise I would give this book five stars. ICON publishes similar books for virtually any disease you can think of, so a lot of the contents are boilerplate, but it's intelligent boilerplate basically dealing with research techniques and sources. The core of the book consists of a discussion of the specific disease and research sources applicable to that disease.

All in all, an excellent book and certainly worth the price. ... Read more

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Univ. of Rochester, NY. Illustrates the success of the relationship between basic and clinical science as demonstrated by new insights into clinical drug resistance and means of circumventing this potential obstacle to effective cancer treatment. ... Read more

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Provides up-to-date information on both the scientific and clinical aspects of work in this area - diagnosis, progress and therapeutics, and the advances in cytogenetics and molecular biology. This book also covers the epidemiology, classification, genetic investigation, immunology, prognosis, treatment, and relationship between MDS and leukaemias. ... Read more

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This book summarizes our current knowledge of MDS, from very basic aspects to the clinical management. It provides guidance to the diagnosis, an understanding of disease mechanisms, and a discussion of treatment strategies.

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 Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias.MDS was previously named as  “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia.

According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged  70  or older. It is believed that the true incidence of MDS have been underestimated however it seems to be comparable to that for multiple myeloma and chronic lymphocytic leukemia.  

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The purpose of the "International Symposium on Myelodysplastic Syndromes - Tokyo 1994" was to discuss the latest advances in myelodysplastic syndromes ranging from such scientific aspects as classification, epidemiology, immunology, cytogenetics, cell biology and molecular biology, to various modes of treatment involving bone marrow transplantation, attenuated chemotherapy and application of hematopoietic growth factors.

The two-day program consisted of invited lectures, selected oral presentations and posters. Lectures by distinguished contributors from abroad provided participants with comprehensive reviews. In addition to a total of 37 oral presentations, 18 posters were presented. A considerable amount of data thus presented by the Japanese investigators in this symposium will prove valuable for hematologists not only in Japan, but also in many other countries worldwide.

Owing to space limitations, a selection of the published pap ... Read more

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Major strides have been made in the treatment and understanding of Myelodysplasia.  The United States Food and Drug Administration (FDA) has approved three new drugs for the treatment of MDS; new disease genes have been discovered; major insights have been made into the biology of the disorder; and animal models of MDS have been developed.  The articles in this issue illustrate the rapid progress in MDS research, from molecular pathophysiology to improved therapies.  Insights into the biology of MDS, the development of model systems to study MDS, and the application of new technologies with unprecedented power to interrogate the cancer genome promise to increase the rate of discovery, transforming our understanding of MDS and leading to improvements in the treatment this disease. ... Read more

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The myelodysplastic syndromes (MDS) are a group of diseases in which the production of blood cells by the bone marrow is disrupted. With around 13,000 new cases a year, MDS surpasses chronic lymphocytic leukemia as the most common form of leukemia in the western hemisphere. This book provides a concise overview of the present state of the art relating to MDS and the latest treatment strategies. ... Read more

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Myelodysplastic syndrome (MDS) is thought to be an incurable disease typified by a clonal disorder in the maturation and proliferation stage of multipotential hematopoietic stem cells. The three main themes in this book are: Influence of cytokines on the maturation and proliferation of normal hematopoietic progenitor cells as well as leukemic cells including those from patients with MDS. Synergisms of cytokines in vitro and in vivo. Clinical features of MDS including BMT. The book provides useful information regarding effective treatments of MDS based on a better understanding of the cytokine actions as well as the association with the hematopoiesis including the network system. ... Read more

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This comprehensive and clear text familiarizes readers with the mostrecent information concerning bone marrow failure syndromes including anemia, leukopenia, and thrombocytopenia. 12 top experts present state-of-the-art guidance on pathophysiology and treatment, with an emphasis on chemotherapy. The result is an Indispensible resource on the treatment of these often life-threatening diseases. ... Read more

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Students, researchers, and patients can find reliable, up-to-date and clearly written information in “The Gale Encyclopedia of Cancer,” a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures.