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This digital document is an article from Family Practice News, published by International Medical News Group on March 1, 2000. The length of the article is 1893 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Meaning Behind Cafe-au-Lait Macules.(Brief Article)(Statistical Data Included)
Author: Barbara Baker
Publication: Family Practice News (Magazine/Journal)
Date: March 1, 2000
Publisher: International Medical News Group
Volume: 30Issue: 5Page: 39

Article Type: Brief Article, Statistical Data Included

Distributed by Thomson Gale ... Read more

Product Description
The article is excerpted fromGale Encyclopedia of Medicine.

Consultthe second edition of this authoritative, comprehensive, in-depthmedical guide for information on more than 1,700 medical topics inlanguage accessible to adult laypersons. Presented in a singlealphabetical sequence, articles range in length from one or twoparagraphs for minor topics, to several pages or more for major topics.Disease/disorder articles typically cover definition; description;causes and symptoms; diagnosis; treatments; prevention; and more.Test/treatment articles typically cover definition; purposes;precautions; preparation; risks; normal and abnormal results; and muchmore. This second edition includes more than 200 new entries, 300updated entries, approximately 650 color images and illustrations, anda comprehensive subject index. New features include biographical andhistorical sidebars throughout the text.

Disease/disorder articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the disorder
• Descriptions -- overview of the disorder; who gets it and why
• Causes & symptoms -- process, substance or organism thatproduces the condition; any risk factors that increase susceptibilityto the condition; signs and symptoms of the disease
• Diagnosis -- overview of procedures and tests used todiagnose the condition; how the test is done; who should be tested andwhen; time required; cost; whether it's typically covered by insurance
• Treatments -- overview of conventional methods of care ormanagement of the condition, such as drugs, surgeries, physicaltherapy, etc.
• Alternative treatments -- overview of alternative/complementary therapies that may be used to treat the condition
• Prognosis -- probable outcome of the disease
• Preventions -- what actions can be taken to prevent the condition from occurring

Test/treatment articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the test/treatment
• Purposes -- why and when this test/treatment is prescribed
• Precautions -- when this test/treatment should not be prescribed
• Descriptions -- overview of the test/treatment including cost,length of time required, procedures followed, whether typically coveredby insurance
• Preparation -- pre-test treatment procedures, if any
• Aftercare -- post-test treatment procedures, if any
• Risks -- any complications/side effects commonly associated with the test/treatment
• Normal results -- for tests, describes the normal values; for treatments, describes the anticipated outcomes
• Abnormal results -- defines abnormal test values

Published/Released: December 2001

Product Description
This digital document is an article from Gale Encyclopedia of Medicine, 3rd ed., brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 2635 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.The third edition of this authoritative, comprehensive, in-depth medical guide features information on medical topics in language accessible to adult laypersons. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. ... Read more

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This digital document is a journal article from Comparative Biochemistry and Physiology, Part C, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Damselfish neurofibromatosis (DNF) is a transmissible disease characterized by peripheral nerve sheath and pigment cell tumors which occurs in bicolor damselfish (Stegastes partitus) on Florida reefs. The damselfish virus-like agent (DVLA) is associated with the development of DNF and contains a 2.4 kb DNA genome which was found at high levels in tumors and tumor-derived cell lines and at lower levels in non-tumor tissues of both spontaneously diseased fish (TF) and fish with experimentally induced tumors (EF). An analysis of transcription patterns revealed up to five DVLA derived RNAs ranging in size from 300 to 1400 bp in these cell types. DNA was the most commonly distributed DVLA component in TF and EF followed by RNA. Prevalence of transcripts varied by tissue type. The smallest transcripts were the most common in all cell types and the most complete patterns, which included the larger transcripts, were observed primarily in tumors. The presence of viral RNAs in addition to DNA in non-tumor tissues suggested these tissues were infected by DVLA and indicated a wide tissue tropism for this agent. The high levels of DVLA nucleic acids found in tumors suggest that replication is occurring there. However, the potential for DVLA replication in other tissues where only a limited range of transcripts were present is not known. The mechanism of tumorigenesis by this agent is unknown. However, the association of the larger transcripts with most tumor tissues and their absence in most non-tumor tissues suggests that these RNAs may be involved in tumor formation. ... Read more

Product Description
Articles include - Neurofibromatosis Type 1 in Genetic Counseling Practice: Recommendations of the National Society of Genetic Counselors / Risky Communication: Pitfalls in Counseling about Risk, and How to Avoid Them / Information Processing in the Context of Genetic Risk: Implications for Genetic-Risk Communication / Results of an Intervention for Individuals and Famalies with BRCA Mutations: A Model for Providing Medical Updates and Psychosocial Support Following Genetic Testing / Health Beliefs and Behaviors of Women Who have Received Genetic Counseling for Breast Cancer / Psychological Follow-up of Presymptomatic Genetic Testing for Spinocerebellar Ataxia Type 2 (SCA2) in Cuba / Parents Perceptions of Functioning in Families Having a Child with a Genetic Condition / Knowledge and Attides Towards Genetic Testing: A Two Year Follow-up Study in Patients with Asthma, Diabetes Mellitus and Cardiovascular Disease / Knowledge and Expectations of Women Undergoing Cancer Genetic Risk Assessment: A Qualitative Analysis of Free-Text Questionnaire Comments / Successful Use of Peer Educators for Sharing Genetic Information / Disclosure of Genetics Research Results after the Death of the Patient Participant: A Qualitative Study of the Impact on Relatives / What do Patients Prefer: Informed Consent Models for Genetic Carrier Testing ... Read more

Product Description
The neurofibromatoses are autosomal-dominant genetic disorders of the nervous system that primarily affect the development and growth of neural cell tissue. These disorders cause tumors to grow on nerves and produce other abnormalities such as skin changes and bone deformities. In recent years, the genes and mutations causing neurofibromatoses have been identified. The main types of neurofibromatoses, type 1 (NF1) and type 2 (NF2), have been shown to be distinctive disorders both clinically and genetically. More recently, allelic and non-allelic subtypes of NF1 have been defined as well as the NF2-related condition schwannomatosis. Many of the complex molecular mechanisms leading to the neurofibromatoses have been elucidated, resulting in a growing body of publications which are difficult to keep up with. This volume provides an important overview of recent findings on the neurofibromatoses. It focuses on the genetics and molecular biology underlying these diseases, but also covers their clinical features, diagnosis and treatment, stressing the need for interdisciplinary medical care. With contributions by the foremost investigators in the field, this timely book will appeal to geneticists, genetic counselors, pediatricians, neurologists and oncologists. ... Read more

Product Description
Traces the history of Joseph Merrick, called the Elephant Man because of a deformity, from his birth in central England to his death in a London hospital in 1890. ... Read more

Customer Reviews (5)

Elephant Man
Book was in very good condition and described perfectly by seller.Thanks.Great transaction.

The (More or Less) True History of the Elephant Man
Unlike the (brilliant) play and movie of the same name, Frederick Drimmer's "fictional biography" of Joseph Merrick, THE ELEPHANT MAN, aims to tell the subject's true life story, based on accounts of those who knew him.I first read THE ELEPHANT MAN as a teenager in high school.Revisiting the book now as an adult, I find there is little I can add to the apt assessment of the reviewer quoted here on Amazon.com.I'll only repeat that Drimmer, an authority on so-called human oddities and a gifted writer, tells Merrick's sad yet inspiring story tastefully and with drama and interest in every chapter.Merrick's humanity and that of his doctor, Frederick Treves, and his other friends shines through brightly, yet the evils present in British Victorian society are not underplayed.Consequently, THE ELEPHANT MAN reads like both a biography and an entertaining work of fiction, suitable for both young and older adults.

Touching reading
I was very touched by the story of the Elephant man, who was very deformed and endured many hardships in his childhood and young adult life because of his appearance. His life becomes bearable though in his end years thanks to the kindness of Dr. Fredrick Treves and many other people. If you haven't heard of or read about the Elephant man yet, I recommend this book, Joseph Merrick's story (the Elephant man) is something you won't forget. The terrors he went through and then how incredibly grateful he was for the simplest pleasures after being rescued by Dr. Treves make me see life through new eyes: it is hard to take things for granted. The book also includes photographs of Joseph.

WHAT I THINK ABOUT THE BOOK
THIS BOOK IS A MUST READ IT IS A TRUE STORY ABOUT A MAN JOSEPH CAREY MERRICK WHO SUFFERED A DISEASE PROTIO-SYNDROM WHICH DISFIGURED HIM. ITS ABOUT HOW HE LIVED AND HOW HE SPENT HIS TIME WITH HIS DOCTOR. THE WHOLE BOOK IS GREAT I FOUND IT VERY INTERESTING AND TOUCHING.BUT IN ALL I WOULD RECOMEND THIS BOOK TO ANYONE. -RANDY

Reveals The Lies Of The Movie
The movie, which I saw when I was 7 was a lie.Tom Norman, his manager in the freak show treated him with great respect and was a portaryed as a monster.He was never stolen from the London Hospital and was not beaten.The movie focused on the bad of his life but not the good.Sir FredrickTreves (forgiven an misspelling,s, I am only 12) the sugeon that helped himwas a great man and help John and brought out the good that most overlookedbecause of his appearance.He is man i would love to personally meet andthis book helped me realize that he was a smart man, a caring man, a lovingman....This book would help anyone interested in this subject with it'sphotos and insight. ... Read more

Product Description
This book has been created for parents who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells parents where and how to look for information covering virtually all topics related to neurofibromatoses (also Bilateral acoustic neurofibromatosis; NF1 is also called von Reckling-hausen disease; NF2 is also called bilateral acoustic neurofibromatosis; Type 2 neurofibromatosis; Von Recklinghausen Disease; Von Recklinghausen neurofibromatosis), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on neurofibromatoses. Given parents' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms. ... Read more

Product Description
Follows the life of Joseph Merrick, called the Elephant Man because of a deformity, from his early years as a sideshow attraction to his death in a London hospital in 1890. ... Read more

Product Description
Documents the life of a Mormon girl in Utah who developed neurofibromatosis at the age of fifteen, and in the six years until her death exhibited great courage, determination, and faith. ... Read more

Product Description
Publisher: London, New York [etc.] Cassell and Company, Ltd.Publication date: 1923Subjects: Merrick, Joseph Carey, 1862-1890Physicians -- Correspondence, reminiscences, etcNeurofibromatosis -- biographyAbnormalities, MultipleNotes: This is an OCR reprint. There may be numerous typos or missing text. There are no illustrations or indexes.When you buy the General Books edition of this book you get free trial access to Million-Books.com where you can select from more than a million books for free. You can also preview the book there. ... Read more

Product Description
This book tells the story of the life of one man who suffered from neurofibromatosis. Through horrible physical deformities which were almost impossible to describe, Joseph Merrick spent much of his life exhibited as a fairground freak until even 19th century sensibilities could take it no more. Hounded, persecuted and starving he ended up being rescued by the distinguished surgeon Frederick Treves. To Treves's surprise he discovered, during the course of their friendship, that lurking beneath the mass of Merrick's corrupting flesh lived a spirit that was as courageous as it had been tortured, and a nature as gentle and dignified as it had been deprived and tormented. ... Read more

Customer Reviews (12)

The best biography of Joseph Carey Merrick
This is definitely the best and most thoroughly researched biography of Joseph Carey Merrick, aka "The Elephant Man." Beautifully written, very readable and thoroughly researched account of a gentle courageous soul trapped inside a body terribly deformed by Proteus syndrome.

Recently, a new edition of this book was issued which purported to contain 'fresh information" on Joseph Merrick. Alas, it is only a paperback version of this 2001 edition, with no new research from 2001 on.Not only that, the photographs in the newer edition are of poor resolution.

This edition remains for now the gold standard of Merrick research, with excellent photographs of Merrick and the important people and places in his life. We can only hope that a newer, more updated biography will emerge from the revelations that have come to light. One of the most prolific websites of up-to-date research topics is the Friends of Joseph Carey Merrick group on Facebook. We also have Jonathan Evans, the latest curator of the London Hospital Archives, to thank for his expertise and devotion to Merrick's legacy.

I highly recommend this edition!

Happy every hour of the day
With twelve viewings so far, David Lynch's "The Elephant Man" has been my favorite movie for about twenty years, indeed one of the very few movies I would call a masterpiece. So it is quite a mystery why I should have waited so long to read this biography of its protagonist, Joseph Carey Merrick, whom the movie, following errors in the source material itself, incorrectly names John.

Having already seen a decent BBC documentary on the subject ("The Curse of the Elephant Man"), I was not totally unaware of the facts of the case, and I already knew for instance that Joseph spent some time in the countryside, something which Lynch decided not to depict in his film so as to achieve a more complete immersion in his bleak, black and white vision of Victorian London (indeed, one type of shock a fan of the movie will encounter while reading the book comes from its occasional touches of colour : I remember being struck by the blue bunsene light that lit the Elephant Man's face when Treves first met him.)

What is most surprising about the book, is how the film managed to be so faithful to Merrick's psychology (Lynch's John is the true Joseph, not some Hollywood fantasy), while altering many elements in the background, most of the secondary characters being dramatically different.

To mention a few of the changes from reality to film :

Joseph's manager as a freak, Tom Norman, was turned by the screenplay into Freddie Jones' very Dickensian Bytes, who beat and exploited his freak. Actually, Tom Norman was one of the few decent persons whom Joseph encountered before his change of fortune, enabling him to save as much as £50 (enough to live for a year without working) over his short career. The true evil was in fact the British government, which decided to ban all exhibitions of freaks as indecent (and references to Joseph's "nakedness" suggests that they may well have been), thereby forcing them out of the market and depriving them of their livelihood. To the writers' discharge, though, it might be argued that the fictional Bytes was a composite of Norman and the evil Austrian impresario who robbed Joseph of his savings in Belgium, which somewhat minimizes the gratuitousness of an all-too-typical Hollywood slur on the entrepreneur.

One of the famous scenes of the movie, in which Joseph attends a pantomime, is asked by Treves to "stand up" before the audience and is applauded by them, is a complete reversal of the true incident. Actually, Joseph attended the show incognito, and the most stringent precautions were taken to keep the rest of the audience unaware of his arrival, presence and departure (but then, the screenwriters needed their second "stand up" scene for dramatic reasons.)

In the film, Anne Bancroft's Mrs Kendal is shown visiting Joseph regularly at the hospital. Actually, the actress never met him in person, though she did send him her photograph and other presents. On the other hand, Princess Alexandra, who is shown much more sparingly in the film, did visit him several times, and send him Christmas cards.

The scene in which Michael Elphick's night porter introduces a bunch of drunks and prostitutes into Joseph's rooms may also be an exaggeration from much more minor real-life incidents. Also, on his return to London, Joseph did not find refuge in the toilets, but in the waiting room of the railway station. As for the model church he made, Lynch hides the fact that Joseph was actually using commercialized cut-and-assemble models from the local bookstore, which the nurses helped him assemble. The film makes it appear that Joseph had some wonderful artistic gift and was very dexterous, whereas his enormous right hand prevented him from even working in the cigar industry.

One thing I was curious about was Joseph's religion, as the film has very little to say about it, or about religion at the hospital in general. His mother was a Baptist, and the Bible was a book he had read several times over. When at the London Hospital, he was "confirmed" by an Anglican "bishop" (I am using scare quotes because as a Catholic I believe Anglican "bishops" are not validly ordained and, being mere laymen, do not have the power to confirm anyone) and allowed to participate in church services at the chapel.

Howell and Ford's book is truly a biography everyone should read. It gives an excellent picture of Victorian London, conditions in Poor Houses, the whole milieu of country fairs and freak shows and life at the London Hospital. It also contains a two-page autobiographical piece by Joseph himself, and the relevant extract from Treves' famous "The Elephant Man and Other Reminiscences", but it is well-researched enough to point out the few errors and inaccuracies in these primary sources themselves. It also corrects erroneous interpretations in Ashley Montagu's earlier book on the subject.

All in all, this is a superb read, which could serve as concrete argument against a culture of death which is too ready to consider some lives not worth living. "Happy every hour of the day", after all, was how Joseph himself described his life at the hospital. And his happiness is one of the things most readers will paradoxically end up envying him.

Integrety & Humility is the Elephant Man story
This book cannot help but touch every human being who reads it! With so many disabled people in our world, and our pre-occupation with appearances and the body beautiful, the elephant man story covers all the physical and emotional aspects of living with an extreme disability with dignity and humility for all readers to experience. Of course the help and support he and others must receive all helps. Peter Ford presents his extensive research findings on those that came to the elephant man's aid in a personable way. Although the film is based on his life, the book reflects Joseph Merrick's life in reality, politely comparing the differences between his film persona and his real life condition. It helped me to fill in the gaps left after watching the film and left me with a thankfulness of how well off my family and I are.

Not for light reading...
The very nature of this topic is difficult to accept given its sadness.However, with only the very-well-made movie to capture its subject, this book helps define everything, thereafter.Nothing can alleviate the weight of its subject matter; but, it does help one to interpret the man, more than the mystique.Ultimately, it makes you glad that Mr. Merrick did have a graceful exit from life given the dire physical deformity that shaped it.

The amazing story of Joseph Merrick.
Very good and in-depth book on the life of not only Joseph Merrick, but also Mr. Treves and many other people who happened into his life. Can you imagine even for one minute being in this guys shoes? I mean can any of us even begin to grasp the sort of life Joseph must of had to deal with? Can you imagine being so utterly repulsive looking (sorry, but he was) that just one glance at your face would make people flee, children cry, and women pass out, I mean think about just how horrible that would have been. He also suffered from chronic pain, and smelled something awful. Yet, beyond that he was such a kind, gentle, shy, caring, lovable and curious individual, who by all accounts would of been completely normal and was highly intelligent. What a life, what a great true story of a very strong determined soul. ... Read more

Product Description
Autism: Beyond the Basics is the long awaited sequel to Dr. William Shaw's Biological Treatments for Autism and PDD, the groundbreaking book which introduced thousands of families throughout the world - touched by autism - to hope for recovery. As an autism researcher, scientist, biochemist, and laboratory director, William Shaw, Ph.D. has worked over a decade to uncover other causes and potential solutions to the autism epidemic. This new book is a compilation of these research efforts and those of other experts. Parents and physicians seeking more answers will find much food for thought to help improve the lives of individuals with Autism Spectrum Disorders. Some of the many topics covered by Dr. Shaw and his contributing authors include: cholesterol deficiency, carnosine therapy, GI abnormalities, lithium deficiency, hyperbaric oxygen treatment, copper/zinc imbalance, chemical and food sensitivities, oxalate toxicity, homeopathy, and methylcobalamin. The information in this book may be useful not only in the field of autism but nearly any disorder in which some of the symptoms of autism are often present, including Pervasive Developmental Disorder (PDD), Attention Deficit Hyperactivity Disorder (ADHD), Williams Syndrome, Down's Syndrome with Autistic Symptoms, Rett's Syndrome, Asperger's Syndrome, Tuberous Sclerosis, Prader-Willi Syndrome, Tourette Syndrome, Fragile X, and Neurofibromatosis.
About the Author
Received a Ph.D. in Biochemistry and Human Physiology and is board certified in Clinical Chemistry and Toxicology. He is known worldwide for his research and presentations at conferences in the field of autism and developmental disorders. Dr. Shaw has been actively involved with both the Defeat Autism Now! and Autism Speaks groups and is a board member of the National Academy for Child Development. He is also the founder and director of The Great Plains Laboratory, Inc. for Health, Nutrition, and Metabolism in Lenexa, Kansas, a laboratory specializing in metabolic, environmental, and genetic testing for people with chronic illnesses and diseases. He published the first edition of Biological Treatments for Autism and PDD in 1998 and it has since been translated into eight different languages and has helped thousands of patients and medical practitioners successfully improve the lives of individuals with autism. ... Read more