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This is an introduction for those professionals and carers concerned with caring for children with special needs. The book is divided into four sections which discuss medical, psychological and pedagogical issues and the organization of education. It describes these factors internationally. This new edition has been updated to take into account recent educational developments, especially in the UK. Medical advances due to detection of disability in the ante-natal stage and possible future cures with developments in genetics are considered. Other disabilities such as AIDS and sickle cell anaemia are mentioned. New material is provided on existing topics such as Still's Disease, writing and spelling, with major revisions to the comparative education section. ... Read more

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Department of Veterans Affairs Medical Center, Syracuse, NY. Focuses on subjects of importance to the neurologist: historical perspective, disorders of development and maturation of sleep, role of melatonin, delayed-sleep-phase syndrome, insomnia, motor disorders, sleep apnea, stroke, headache disorders and more. ... Read more

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This is the first evaluative discussion of the use ofneurotoxins to produce animal models of Alzheimer's, Parkinson's,Huntington's andother human neurodegenerative diseases. The workalso responds tocriticisms of the use of animals in biomedicalresearch by examiningthe utility, validity, and limitations of themodels presented. Anexcellent resource for researchers and studentsin the neurosciencesand environmental toxicology interested in boththe practical andethical aspects of animal research. ... Read more

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This reference discusses state-of-the-art methods for the management of children with conditions affecting the nervous system-providing over 80 chapters that outline direct, logical approaches to numerous pediatric neurologic disorders using clear tables, algorithms, and figures for quick reference to key material. ... Read more

Customer Reviews (2)

Treatment only
It concentrate on treatment as it implies but not enough on the disease it's self, so i had to buy an other one which does. Not enough for neurology resident. Written in simple non-borring language. Covers treatment effeciently.

A perfect, concise reference for management
I bought this as resident, loved it--provides a concise review of the selected topics, with references, then outlines current best practice.Not exhaustive by any means, and will become outdated over time, but otherwise I think it is excellent for residents and practictioners who have little time to initiate diagnostic or management plans. ... Read more

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Clinical neuropsychology is a sub-specialty of clinical psychology that specialises in the diagnostic assessment and treatment of patients with brain injury or neurocognitive deficits. This book comprises contributions from different clinical domains, in particular neurology, psychology and psychiatry and summarises significant theoretical and above all, practically usable information regarding a variety of disorders that a clinical neuropsychologist comes across in practice. This book explores aetiology of cognitive deficit, history of its examination, variables that are concerned with cognitive functions and rehabilitation possibilities. All chapters were written by experienced clinicians who are used to prevailing, typical problems of their patients that overlap cognitive functions to domains such as emotions and everyday difficulties of problem solving. This book is useful for individuals interested in neuropsychological diagnostics and rehabilitation, students of psychology and alike-oriented professions. ... Read more

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This volume provides readers with a comprehensive description of phospholipid metabolism in brain, activities of phospholipases A₂, and their involvement in neurological disorders. The purpose of this book is to present readers with cutting edge information in a lively manner that is useful not only to student and teachers but also to researchers and physicians. This book has 14 chapters that will describe (1) the metabolism in brain of glycerophospholipids, including those containing a vinyl ether group (plasmalogens); (2) cutting edge information on the properties and roles of phospholipases A₂ in the central nervous system; (3) the release by phospholipases A₂ of second messengers (arachidonic acid, docosahexaenoic acid, and lysophospholipid) from neural membrane phospholipids and their neurochemical effects on brain metabolism and functions; (4) the involvement of phospholipases A₂ in neurological and neuropsychiatric disorders, and the use of phospholipase A₂ inhibitors for the treatment of diseases associated with altered phospholipid metabolism; and (5) methods for the assays of phospholipases A₂ and their clinical significance.

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This volume brings together scientists and clinicians fromdiverse disciplines for discussions of oxidative injury in the nervoussystem. Areas of examination include: +a reviewof metals and their role in oxidative injury, with special attentionpaid to iron+the mechanisms by which the brain protects itselffrom oxidative harm+the clinical diseases in which oxidativeinjury is known to contribute to the pathogenic process+ antioxidant therapeutic strategies in neurological disorders, and +a proposed common pathway for oxidative injury in thebrain. ... Read more

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Distinguished medical researchers from around the world review novel neural reconstructive techniques that appear to be beneficial for Parkinson's disease and hold promise for treating Huntington's disease, pain, demyelinating diseases, and stroke. The contributors focus on those diseases for which clinical trials are either ongoing or likely to occur in the near future. Among the topics reviewed are results and rationale for some of the leading transplant programs for the treatment of Parkinson's disease, the use of PET scanning for patient evaluation, autopsy studies of transplant recipients, transplant immunology, fetal tissue transplantation for Huntington's disease, cellular transplantation for the treatment of pain and stroke, and transplantation of myelinating cells. A full discussion of the important ethical issues surrounding the use of fetal tissue for transplantation purposes is also included.

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This reference work describes the natural history of the most common types of neurological disease and the impact of treatment on the course of illness, enabling clinicians to make better predictions about their patients' future. In the Second Edition, the editors will focus more sharply on this subject, reducing the overlap with standard textbooks of neurology. They will also add three chapters on outcomes assessment, medico-legal aspects, and metabolic disorders. ... Read more

Customer Reviews (1)

Review
This is a fine book, and this updated version is well laid out, well written, very readable, and is useful for neurologists, neurosurgeons, other physicians, neuropsychologists, clinical psychologists, andrehabilitation specialists. ... Read more

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Many diseases of the nervous system are difficult to treat but can be prevented when we have adequate genetic information. This new edition continues to provide comprehensive coverage of the genetics of neurological disorders. It conveys practical clinical advice to neurologists, geneticists and pediatricians, emphasising diagnosis, mode of inheritance and recurrence risks, to enable them to understand clinical situations and counsel correctly. Michael Baraitser is an expert in this field, and this edition includes recent advances in molecular genetics and the newest discoveries in gene location and identification. ... Read more

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Protocols for Gene Transfer in Neuroscience Towards Gene Therapy of Neurological Disorders Edited by P. R. Lowenstein University of Manchester, UK and L. W. Enquist Princeton University, USA The brain and the cells that compose it have always presented unique barriers to any kind of outside interventions, including drug delivery, surgical procedures and the genetic manipulation of cells. However, these barriers are now being bypassed by the new technology of gene delivery. Protocols for Gene Transfer in Neuroscience is the first practical guide to gene delivery, providing over 150 easy to follow, step-by-step protocols, together with troubleshooting hints and the theoretical background needed for neuroscientists to understand, adapt and expand the technology as needed. Written by a team of international expert neuroscientists, geneticists, molecular biologists and biochemists, Protocols for Gene Transfer in Neuroscience describes the latest techniques from the top gene-delivery labs, ranging from physical transfection techniques, through the use of a wide range of viral vectors, to retrovirally transduced cell and bone marrow transplantation. Several variations of a single protocol are given, thus demonstrating how different labs have solved a common problem in different ways. The protocols are also indexed and cross-referenced so that an investigator can find all the details required for a particular problem. ... Read more

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Fifteen chapters, written by experts in the field, summarize current studies that involve receptors and ligands in neurological disorders.The advance in the study of receptors in general enables investigators to explore the mechanism of action of psychotropic drugs and to minimize their side effects.It will lead to the study of molecular events and an understanding of the nature and cause of the various diseases and to more accurate diagnoses that may give more effective therapeutic treatments. Topics discussed include the role of central dopamine in movement disorders, aluminum and Alzheimer's disease, receptor binding in the kindling model of epilepsy, and cholinergic neurons in Huntington's disease.The chapters have been carefully edited for a wide appeal to pharmacologists, neurologists, and neuroscientists. ... Read more