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Whether you re a newly diagnosed pancreatic cancer patient, a survivor, or a friend or relative of someone with pancreatic cancer, this book offers help. The only text to provide a doctor s and patient s view, 100 Questions & Answers About Pancreatic Cancer, Second Edition gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. The authors, a medical oncologist and a nurse with 25 years of experience with cancer patients, provide a comprehensive, step-by-step discussion of what you can expect in the diagnosis and treatment of pancreatic cancer, while patient commentaries provide a real-life understanding of what these steps might mean for your day-to-day life. This book is an invaluable resource for anyone coping with the physical and emotional turmoil of this disease. ... Read more

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The Johns Hopkins Patients’ Guide To Pancreatic Cancer Is A Concise, Easy-To-Follow “How To” Guide That Puts You On A Path To Wellness By Explaining Pancreatic Cancer Treatments From Start To Finish. It Guides You Through The Overwhelming Maze Of Treatment Decisions, Simplifies The Complicated Schedule That Lies Ahead, And Provides Valuable Tools To Help You To Put Together Your Plan Of Care. Empower Yourself With Accurate, Understandable Information That Will Give You The Ability To Confidently Participate In The Decision Making About Your Care And Treatment.About The Series:Learning That You Or Someone You Love Has Cancer Is Devastating, And Feeling Lost And Powerless Is A Common Immediate Response. The Johns Hopkins Patients’ Guides Are Designed To Alleviate Your Anxiety, Empower You With Information, And Enable You To Fully Understand Your Treatment Options. Each Book In This Series Is Dedicated To A Specific Type Of Cancer. The Information Is There To Help Lighten Your Burden And To Assist You In Becoming An Active Participant In Your Care. Cancer Rarely Allows Us To Take A Diversion From Life, And Offering Guidance On How To Continue To Live Life While Working Hard On Getting Well Is Part Of The Outcome We Hope To Help You Achieve. ... Read more

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Beat the 5% survival rate after 5 years
1. The Pancreas produces insulin.Bile ducts passing from the liver travel through the head of the Pancreas.The pancreas is made of a collection of hormone producing cells called lobules.Lobules are composed of acinar cells that are exocrine producing cells hat produce the digestive enzymes and fluids released into the small intestine.
2. Cancer research of the pancreas is the lowest of all major cancers holding at $1,145 per patient.Only 3% of the National Cancer Institutes research budget is spent on pancreatic cancer
3. The k-Ras mutation of genes in the pancreas is associated with 95% of the adenocarcinomas of the pancreas.Gene therapies attaching to the k-Ras mutation may help the immune system destroy the cancer.Pancreatic cancer also has inactivation of the p53 gene, a tumor suppressor gene.
4. The Breast cancer gene BRCA2 is strongly related to the development of pancreatic cancer.
5. Smoking is strong associated with the early onset of pancreatic cancer.The Pallidin gene can cause mutations leading to pancreatic cancer.
6. Pancreatic cancer is common among African Americans
7. Being overweight, eating large amounts of red meats, and alcohol increase the risks of Pancreatic cancer.
8. The computed tomography (CT) scan is the most common diagnostic tool for pancreatic cancer.The endoscopic retrograde cholangiopancreatography (ERCP) uses a dye injected into the pancreatic ducts to search for tissue abnormalities.The endoscopic ultrasound uses sound to produce images of the pancreatic ducts.
9. Pancreatic cancer symptoms may include: bile reduction causing food not to digest, jaundice and elevated liver enzymes, pale stools and dark urine, pain in the abdomen or back and weight loss, and diabetes.
10. Cancer at the head of the pancreas can be removed by a process called pacreatoduodenectomy.The head of the pancreas is removed, most of the duodenum, a portion of the bile duct and sometimes portion of the stomach.
11. Gemacitabine is the most effective chemotherapy drug for pancreatic cancer.Fluorouracil (5-FU) chemotherapy is also used with metastatic pancreatic cancer.
12. 3D conformal radiation using CT create digital model of the tumor that can be treated very specifically.X-ray technicians can shape multiple radiation beact to the exact contour of the treatment area and minimize damage to health tissue.
13. In 2007, scientist discovered pancreatic cancer stem cells.They are studying the stem cells for strengths and weaknesses looking for an Achilles heel.
14. The cancer recurrence gene NAC-1 is being studied for properties of tumor suppression.
15. John Hopkins has identified a tumor suppressor gene DCP4 which is missing or inactivated in more than half the patients with pancreatic cancer.
16. Capsaicin cause pancreatic cancer cells growth to slow and tumors to shrink through a process called apoptosis; the bodies way to disposing of damaged or unneeded cells.
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Pancreatic cancer is the fourth leading cause of cancer death in the United States. Every year, about 33,700 people in the United States will be diagnosed with pancreatic cancer and over 32,000 patients will die from the disease. The median survival of patients with advanced pancreatic cancer is about 6-months. This dismal picture of pancreatic cancer is mainly due to the lack of early diagnosis and effective treatment for patients with advanced disease. To increase the survival rate of pancreatic cancer patients, better tumor markers for diagnosis and new molecular targets for drug development are desperately needed. A lot of effort has been made in searching for pancreatic cancer-causing genes or genes associated with progression of malignant behavior in pancreatic cancer. As a result, alterations in the expression of several cancer-related genes have been identified in pancreatic tumors. The identification and characterization of these cancer-related genes have significantly increased our understanding of pancreatic cancer development, but unfortunately the treatment of pancreatic cancer has not advanced as much in the past 20 years.

Over the past decade, tremendous advances have been made in the field of cancer drug discovery, particularly, in the area of molecular and genetic models and technologies. Many of those advanced models and technologies have been applied to the drug discovery processes for pancreatic cancer. In this book, a team of experts will describe the latest development in the application of these models and technologies in pancreatic cancer. The authors include basic researchers as well as clinicians who work in the front-line of the war against pancreatic cancer and have the first-hand experience on these cutting-edge tools and techniques. The book can be divided into two general areas: 1) model systems and 2) genomics and proteomics tools. In recent years there have been a lot of advances in the model systems for pancreatic cancer, including the further characterization of normal and cancerous pancreatic cell lines, the establishment of transgenic mouse models that recapitulate the initiation and progression of human pancreatic cancer, the development of a new xenograft model system for the evaluation of novel agents, and the establishment of a zebrafish pancreatic cancer model. The first four chapters of the book will be devoted to these models. The advances in genomics and proteomics research have made a major impact in cancer drug discovery. A number of these –omics-based tools and techniques have been applied in the pancreatic cancer drug discovery. Chapters 5-9 of the book will discuss techniques for genome-wide examination of gene expression, copy number, methylation, function and regulation. Chapters 10-11 will discuss in situ techniques for studying chromosomal and gene copy number abnormalities as well protein expression changes in cancer samples. Chapters 12-14 will focus on techniques for global examination of protein expression levels in biospecimens obtained from pancreatic cancer patients. Cancer drug discovery has become more and more target-centric.

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This is not another book about cancer. The 22 contributors from 20 families who have contributed their stories, their feelings and their advice have done so in order to help others feel that they are not alone.They represent spouses, siblings, adult children and patients themselves.There are 4 survivors as of the writing of this book.In addition, all proceeds from the sale of this book will be going to the Lustgarten Foundation and the Pancreatic Cancer Action Network that offer support and research for an eventual cure of this deadly disease.
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Written by a team of expert authors from all members of the multidisciplinary cancer care team, Pancreatic Cancer summarizes our current understanding of the epidemiology, genetics, imaging and treatment of these complex malignancies. Each imaging modality is reviewed, with an emphasis on MDCT, MRI and EUS; the key aspects of image interpretation are covered. Separate chapters focus on diagnosis and staging of ductal adenocarcinoma, cystic pancreatic neoplasms and neuroendocrine tumors; rare neoplasms and benign pancreatic disorders that mimic pancreatic cancer are also considered. All treatment options are discussed in detail, including surgery, chemotherapy and radiation therapy, and the multidisciplinary approach to patients with more advanced disease is fully reviewed. This volume is a state-of-the-art review of current practice and knowledge of pancreatic cancer. ... Read more

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Since the previous M.D. Anderson Solid Tumor Oncology Series publication on pancreatic cancer, there have been major advances in our understanding of molecular events which underlie pancreatic cancer development, both in the sporadic and inherited forms. We have seen the development of the first mouse models that accurately recapitulate features of the human disease. Several landmark clinical trials in both resectable and metastatic pancreatic cancer have been completed, raising new questions about the standard of care in this disease. Finally, the era of targeted biologic therapies has engendered new excitement about the prospects of more rapid progress in understanding and successfully treating this dreadful disease. Therefore, it is an appropriate time to review these important advances and outline areas of controversy and question in pancreatic cancer biology and treatment.

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An updated A-Z reference of pancreatic cancer
A must-to-have reference for surgical oncologists, written by pioneers in the field from the world class MD Anderson Cancer Center.
The controversial issues related to treatment options are nicely written ... Read more

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Worldwide, there are an estimated 232, 000 new cases of pancreatic cancer annually. In the United States, it is the fourth leading cause of cancer death, and approximately 30,000 people die of pancreatic cancer each year. The disease is difficult to diagnose in its early stages, and most patients have incurable disease by the time they present with symptoms. The overall 5-year survival rate for this disease is less than 5%.

In organizing this handbook, Dr. Neoptolemos and his co-editors will produce a distinguished Major Reference Work devoted to pancreatic cancer. This handbook will have widespread appeal among clinicians, pathologists and basic scientists who are now struggling to understand this complex and rapidly expanding field.

Because of the recent and vast growth in both the clinical and scientific research being done in pancreatic cancer (there is currently an unprecedented investment by academia and industry in this field), each researcher’s knowledge of other specialty areas outside his or her own is now often quite limited. The aim of this book is to place these the tangible advances—those that are indispensable to all working on pancreatic cancer—readily at hand. The book will focus on advances that will not become dated, and the editors will choose authors who are the very best in each area.

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This book is shared to help all understand the cancer affecting the pancreas which is a vital organ in the digestion of food. Pancreatic cancer is one of the most deadly of cancers affecting the human body. Less than 5% of those diagnosed with Pancreatic Cancer survive the first year.This book is intended to help the patient, their families, and friends to understand the dangers and possible treatments. It is vital that the patient and their families understand the importance of choices of treatment and the possible side effects.This is basically a diary of one patient who has been able to survive five (5) years at this writing. The road can be challenging, but healing is possible if discovered and treated quickly. This book will help the patient and their families to better deal with this deadly disease. ... Read more

Customer Reviews (2)

Encouraging and helpful
This book is a combination of the author's experience, practical advice and the encouraging use of faith to fight cancer. It is helpful and interesting.

Pancreatic Cancer book that is a loser
I was looking to buy an informational book on Pancreatic Cancer to help me and my wife understand this Disease and your description of this book seemed to fit my needs.Instead this is a book written by a religious nut discussing his faith and prayer sessions and how he enlisted 100 other like minded people with the same leanings to pray for him then how they prayed for each other etc.Not what I wanted and not what you advertised. ... Read more

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The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons. ... Read more

Customer Reviews (1)

How do you feel about charging so much for a book for desperate readers?
Is it worth the money knowing people dying of this cant afford the info that would provide a little relief? ... Read more

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EMPOWER YOURSELF!Whether you’re a newly diagnosed pancreatic cancer patient, a survivor, or a friend or relative of someone with pancreatic cancer, this book offers help. The only text to provide a doctor’s and patient’s view, 100 Questions & Answers About Pancreatic Cancer gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. The authors, a medical oncologist and a nurse with 25 years of experience with cancer patients, provide a comprehensive, step-by-step discussion of what you can expect in the diagnosis and treatment of pancreatic cancer, while patient commentaries provide a real-life understanding of what these steps might mean for your day-to-day life. This book is an invaluable resource for anyone coping with the physical and emotional turmoil of this frightening disease. ... Read more

Customer Reviews (3)

Updated edition would be quite helpful
With a '100 Question' format, the book is quite thorough with respect to a variety of considerations - treatments (surgery, chemo, radiation, etc.), diet, physical activity, side effects, and caregiver info.However, there have been significant medical developments in '07, '08 & '09 regarding treating PC.An updated edition of this book capturing more recent medical technologies would be a substantial improvement.

Perfect combination medical and layman
informative book for anyone diagnosed with pancreatic cancer, no matter the stage, and/or concerned family, friends, etc.despite a bleak outcome in my family situation, this book will be helpful to all of us, strongly recommend!

100 Questions & answers about Pancreatic Cancer,
I think all the books I ordered were very good and informative. ... Read more

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This ambitious collection of essential yet novel methods for pancreatic cancer research or cancer research in general features an outstanding cast of authors who are esteemed leaders in the field. The authors provide a broad range of methods for molecular, biochemical, pathological, and statistical analysis of sporadic and familial pancreatic cancer, methods that can be applied not only to basic, but also to translational pancreatic research. Topics covered include in vitro cell cultures, in vivo mouse models, protein studies, mutation analysis, and treatment development. ... Read more

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Written by two expert oncologists specializing in pancreatic cancer, Dx/Rx: Pancreatic Cancer is a concise pocket reference for all professional caregivers of patients with pancreatic cancer. This handy guide provides comprehensive, up-to-date information on the epidemiology, symptoms, diagnosis, and management of malignancies of the pancreas. Topics include detailed outline of the diagnosis process and staging, molecular pathogenesis, localized diseases and advanced cases, metastatic pancreatic cancer, uncommon pancreatic malignancies, and information on supportive care. Presented in a quick-reference format, Dx/Rx: Pancreatic Cancer is an essential guide for on the ward or in the clinic. ... Read more

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This volume consists of contributors to the Pacabrum '95 Meeting on Pancreatic Cancer, March 1995, Birmingham. The chapters represent comprehensive scientific advances rather that symposium proceedings. Pancreatic cancer is the fourth commonest cause of cancer death in Europe and North America and its incidence appears to be on the increase. Due to its rapid growth and silent course, diagnosis is often only established in the advanced stages, resulting is a poor prognosis. In addition, it is one of the most aggressive malignancies; treatment of this disease, therefore, is a great challenge to clinicians world-wide. Whilst existing surgical and medical treatments have undergone much development in recent years, improving the outcome for many patients, there has been a great many advances in the understanding of the molecular and genetic basis of the disease, and the clinical applications of this knowledge to areas such as gene therapy. This book is divided into three sections covering each of these in turn: "Molecular pathophysiology of pancreatic cancer"; "Genetic advances and their clinical applications"; and "Clinical management of pancreatic cancer".With international contributors, this title should provide a comprehensive overview of the current status of pancreatic cancer for both clinicians and researchers. It describes the latest developments in the clinic and the laboratory for this important tumour type. Advances in our understanding of the genetic and molecular events involved in the disease have led to improvements in diagnosis and assessment, as well as the prospect of novel therapies. Novel radiological techniques allow safer and more effective imaging and intervention for malignant obstruction while specialist surgical management now offers selected patients a real chance of cure. The international experts in each of these fields have produced a comprehensive and critical review which integrates the clinical problem with basic scientific research. ... Read more

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Although pancreatic cancer is one of the most serious forms of cancers, the lack of clinical symptoms often limits curative treatment options. This book gives insight into the current understanding of the management of pancreatic cancer and considers recent findings in cancer research. It provides answers to questions of how to know when cancer is respectable, how to proceed when the diagnosis comes too late for a curative approach, and how to assess different study results.

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At present, there are approximately 28,300 new cases of pancreatic cancer in the United States. It is the fourth leading cause of cancer death in men and women. Approximately 2 out of 10 patients with cancer of the pancreas will live at least one year after the cancer is found, but only a very few will survive for five or more years. The editors have brought together a stellar team of oncologists from surgery, medicine, and radiation therapy to provide a concise yet thorough guide to the understanding and management of pancreatic cancer. From epidemiology and genetics to diagnosis, management, and reconstruction, coverage of the subject is inclusive. ... Read more

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Univ. of California, Los Angeles. Discusses the latest techniques for genetic screening for pancreatic cancer, the value of tumor antigens, advances in diagnostic radiology, and the roles of laparoscopic and palliative endoscopic stenting. For basic scientists and clinicians. Halftone illustrations. ... Read more

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This issue of the Surgical Oncology Clinics will cover the following topics: imaging for pancreatic cancer, EUS staging and novel therapeutics for pancreatic cancer, management of cystic tumors, management of IPMN, laparoscopic surgery for pancreatic tumors, current concepts in the surgical management of pancreatic cancer, management of borderline resectable pancreatic cancer, regionalization of pancreatic surgery, update on adjuvant trials for pancreatic cancer, neoadjuvant therapy for pancreatic cancer, novel targets for pancreatic cancer therapy, and new frontiers in pancreatic cancer. ... Read more

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