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This digital document is an article from Gale Encyclopedia of Medicine, 3rd ed., brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 1742 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.The third edition of this authoritative, comprehensive, in-depth medical guide features information on medical topics in language accessible to adult laypersons. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. ... Read more

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Purchase includes free access to book updates online and a free trial membership in the publisher's book club where you can select from more than a million books without charge. Chapters: Potter Sequence, Polycystic Kidney Disease, Dent's Disease, Meckel Syndrome, Nephronophthisis, Epispadias, Horseshoe Kidney, Bladder Exstrophy, Ectopic Ureter, Renal Agenesis, Urachal Cyst, Multicystic Dysplastic Kidney, Megaureter, Papillorenal Syndrome, Medullary Sponge Kidney, Renal Ectopia. Excerpt:Bladder exstrophy Bladder exstrophy , more properly, the exstrophy-epispadias complex is a congenital anomality in which part of the bladder is present outside the body. It is rare, occurring once every 40,000-50,000 live births with a 2:1 male:female ratio. The diagnosis involves a spectrum of anomalies of the lower abdominal wall, bladder, anterior bony pelvis, and external genitalia. It occurs due to failure of the abdominal wall to close during fetal development and results in protrusion of the posterior bladder wall through the lower abdominal wall. Treatment is with surgical correction of the defect, but patients can still have long term issues with urinary tract infections and sexual dysfunction. Pathogenesis The cause of bladder exstrophy is maldevelopment of the lower abdominal wall, leading to a rupture which causes the bladder to communicate with the amniotic fluid. Spectrum of anomalies The typical manifestation of exstrophy-epispadias complex is The spectrum of disease extends from spade penis and epispadias on one hand, to exstrophy with cloaca (also known as cloacal exstrophy ). Treatment Modern therapy is aimed at surgical reconstruction of the bladder and genitalia. Prognosis Even with successful surgery, patients may have long-term problems with References (URLs online) Websites (URLs online) A hyperlinked version of this chapter is at Dent's disease Dent's disease (or Dent disease ) is a rare X-linked recessive inherited condition that affects the kidney . It ... ... Read more

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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing. Since only the smallest fraction of information dealing with polycystic kidney disease is indexed in search engines, such as www.google.com or others, a non-systematic approach to Internet research can be not only time consuming, but also incomplete. This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

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Chapters: Cowpox, Hyperthyroidism, Toxoplasmosis, Autosomal Dominant Polycystic Kidney, Toxocariasis, Hypertrophic Cardiomyopathy, Rabies, Diabetes in Cats and Dogs, Keratoconjunctivitis Sicca, Dirofilaria Immitis, Hip Dysplasia, Felin Coronavirus, Lymphoma in Animals, Corneal Ulcers in Animals, Feline Immunodeficiency Virus, Osteosarcoma, Mastocytoma, Bladder Stone, Feline Leukemia Virus, Mammary Tumor, Coccidia, Feline Calicivirus, Polyneuropathy in Dogs and Cats, Vaccine-Associated Sarcoma, Feline Viral Rhinotracheitis, Capillaria Aerophila, Thelaziasis, Feline Infectious Peritonitis, Feline Lower Urinary Tract Disease, Ectopia Lentis, Familial Renal Disease in Animals, Thelazia Callipaeda, Capillaria Plica, Pyometra, Portosystemic Shunt, Feline Panleukopenia, Protothecosis, Feline Odontoclastic Resorptive Lesion, Cheyletiella, Feline Cystitis, Luxating Patella, Feline Hepatic Lipidosis, Cytauxzoonosis, Epilepsy in Animals, Florida Keratopathy, Eye Proptosis, Otitis Externa in Animals, Ear Mite, Eosinophilic Granuloma, Fibrosarcoma, Feline Acne, Heart Valve Dysplasia, Feline Asthma, Cerebellar Hypoplasia, Dipylidium Caninum, Cat Skin Disorders, Feline Spongiform Encephalopathy, Miliary Dermatitis, Mycobacterium Lepraemurium, Hyperesthesia, Cat Flu, Chlamydophila Felis, Toxocara Cati, Feline Hyperesthesia Syndrome, Flea Allergy Dermatitis. Source: Wikipedia. Pages: 373. Not illustrated. Free updates online. Purchase includes a free trial membership in the publisher's book club where you can select from more than a million books without charge. Excerpt: Toxocariasis is a zoonotic, helminthic infection of humans caused by the dog roundworm (Toxocara canis) or cat roundworm (Toxocara cati). Humans normally become infected by ingestion of embryonated eggs (each containing a fully developed larva, L2) from contaminated sources. Humans are accidental hosts, which inhibits L2 larvae maturation within humans. There are three main ...More: http://booksllc.net/?id=884829 ... Read more

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This up-to-date electronic book on CD-ROM provides the best collection available anywhere of official Federal government information and documents on the subject of kidney disease, including: Kidney Failure, End-Stage Renal Disease (ESRD), Kidney Dialysis, Transplantation, Polycystic Kidney Disease. (Kidney stones, and kidney cancer, are covered by other titles in this series.) This CD-ROM uses next-generation search technology that allows complete indexing and makes all files on the disc fully searchable. For patients, practical information is provided in clearly written patient education documents. For medical professionals, doctor reference tools and texts have detailed technical information and clinical background material.

This thoroughly researched collection presents vital information from many authoritative sources: National Institutes of Health (NIH), Centers for Disease Control (CDC), the Combined Health Information Database (CHID), the Food and Drug Administration (FDA), and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Contents include clinical and medical information, with information on signs, symptoms, testing, diagnosis, treatment, and more.

In addition, as a bonus we have included an encyclopedic collection of general medical and health documents – thousands of pages with extensive material from the NIH on hundreds of diseases and health topics from A to Z, along with government consumer healthcare tips, disease prevention programs, dietary guidelines, and travelers’ health information. Since navigating the Internet to find additional non-governmental medical information can be confusing, we've also provided our exclusive "Guide to Leading Medical Websites" with updated links to 73 of the best sites for medical information! By using weblinks on the CD-ROM, you can quickly check for the latest clinical updates directly from the government.

This CD-ROM has over 46,000 pages reproduced using Adobe Acrobat PDF software and Reader software is included. Advanced search and indexing features are built into our reproduction, providing a complete full-text index. This enables the user to search all the files on the disk at one time for words or phrases using just one search command! The Acrobat cataloging technology adds enormous value and uncommon functionality to this impressive collection of government documents and material. There is no other reference that is as fast, convenient, comprehensive, and portable!

Our CD-ROMs are privately-compiled collections of official public domain U.S. government files and documents - they are not produced by the federal government. They are designed to provide a convenient user-friendly reference work, utilizing the benefits of the Acrobat format to uniformly present thousands of pages that can be rapidly reviewed or printed without untold hours of tedious searching and downloading. This book-on-a-disc makes a superb reference work and educational tool for patients and their families, physicians, and other medical professionals. (Information on this CD-ROM is NOT a substitute for professional medical advice; of course, readers are urged to consult with a professional health care provider for any suspected illness.) ... Read more

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This digital document is an article from Nephrology Nursing Journal, published by Jannetti Publications, Inc. on January 1, 2009. The length of the article is 5496 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.

From the author: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetic cause of chronic kidney disease (CKD) and renal failure in adults. CKD is increasingly managed within a primary care setting, and thus, it is important for primary care providers (PCPs) to be aware of ADPKD. Diagnosis of ADPKD is usually made based on kidney imaging studies and genetic testing. Treatment of ADPKD is a challenge for PCPs and should be managed collaboratively with a nephrologist. This article describes a case study of a patient with ADPKD who is managed by a family nurse practitioner (FNP) and a nephrologist. Through the examination of this complex case, a continuum of care can be arranged for the patient through the end of life.

Citation Details
Title: Autosomal dominant polycystic kidney disease: a case study.(Continuing Nursing Education)(Case study)
Author: Angela Phillips
Publication: Nephrology Nursing Journal (Magazine/Journal)
Date: January 1, 2009
Publisher: Jannetti Publications, Inc.
Volume: 36Issue: 1Page: 41(8)

Article Type: Case study

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This digital document is a journal article from Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Abstract:
Repetitive DNA sequences are abundant in eukaryotic genomes, and many of these sequences have the potential to adopt non-B DNA conformations. Genes harboring non-B DNA structure-forming sequences increase the risk of genetic instability and thus are associated with human diseases. In this review, we discuss putative mechanisms responsible for genetic instability events occurring at these non-B DNA structures, with a focus on hairpins, left-handed Z-DNA, and intramolecular triplexes or H-DNA. Slippage and misalignment are the most common events leading to DNA structure-induced mutagenesis. However, a number of other mechanisms of genetic instability have been proposed based on the finding that these structures not only induce expansions and deletions, but can also induce DNA strand breaks and rearrangements. The available data implicate a variety of proteins, such as mismatch repair proteins, nucleotide excision repair proteins, topoisomerases, and structure specific-nucleases in the processing of these mutagenic DNA structures. The potential mechanisms of genetic instability induced by these structures and their contribution to human diseases are discussed. ... Read more

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This digital document is an article from Medical Update, published by Benjamin Franklin Literary & Medical Society, Inc. on September 1, 1996. The length of the article is 1200 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Remembering Erma. (Erma Bombeck)(Obituary)
Author: Wendy R. Braun
Publication: Medical Update (Newsletter)
Date: September 1, 1996
Publisher: Benjamin Franklin Literary & Medical Society, Inc.
Volume: v20Issue: n3Page: p4(1)

Article Type: Obituary

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