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Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides an authoritative discussion of strategies to effectively implement and interpret the new ASCO/NCCN directives. Standing as the only up-to-date source to readily examine exciting new translational science findings regarding the biology of cancer-associated thrombosis, as well as new clinical recommendations, this guide supplies an authoritative and current discussion of the mechanisms, management, and prevention of cancer-associated thrombosis.

Written alongside the development of the ASCO guidelines in order to fully examine and address the entire breadth of published literature on the topic, this reference explains to specialists how to identify risk factors associated with cancer-associated thrombosis and improve patient outcomes…tracks the development and utilization of low-molecular weight heparins (LMWHs) in the prevention and treatment of cancer-associated thrombosis…contains a summary of the ASCO VTE guidelines by the Co-Chair of the ASCO Panel…offers an executive summary section in each chapter that highlights critical information…provides an at-hand overview of recent translational studies on mechanisms including the linkage of thrombosis with angiogenesis, role of tissue factor, risk assessment, screening, etiology, and emerging therapies. ... Read more

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Foothills Hospital, Calgary. Text correlating current laboratory and clinical knowledge of thrombotic disorders to assist in the prevention and treatment of systemic and venous thromboembolism. For cardiologists, internists, and primary care physicians. 63 contributors, 28 U.S. DNLM: Thrombosis. ... Read more

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University of Wales, Cardiff, U.K. New edition of a comprehensive, two-volume reference on hemostatic and thrombotic disorders, for clinicians. Well-referenced. Halftone illustrations. Previous edition 1987. 97 contributors, 20 U.S. ... Read more

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This practical and clinically oriented book provides a panorama of recent clinical, diagnostic and therapeutic information on thromboembolism in the various vascular territories of the arterial and venous circulation. Generously illustrated with photographs, CT-scanning, drawings and tables, this is a particularly well organised and authoritative book primarily designed for clinicians. ... Read more

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A volume of current reviews of not only the biochemistry, molecular biology and physiology of Protein C, but also the clinical aspects, diagnosis and treatment in relation to hereditary thrombophilia. ... Read more

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The Textbook of Coronary Thrombosis and Thrombolysis, inessence, represents a heartfelt gift of knowledge from a dedicatedgroup of scientists and clinicians, who collectively have set out on amission to minimize the societal impact of `hemostasis in the wrongplace.' The book is divided into four distinct sections: Part 1:Scientific Principles lays a supporting foundation; Part 2: ClinicalApplication of Scientific Principles places the knowledge base in aworking perspective, directly applying science in patient care; Part3: New Dimensions provides a glimpse of tomorrow, steering the fieldclear of self-proclaimed victory and the dangers of complacency as wemove into the 21st Century, and Part 4: The Evolution ofThrombocardiology focuses on laboratory standards, clinical trials anddrugs in development. The major sections are systematically dividedinto smaller sections, each with a composer who has been asked toassemble the finest scientific minds in the world. When broughttogether and conducted well, the orchestra plays a symphony for allthe world to hear. It is this spirit that captures the pain of humandisease and suffering, rising swiftly to meet the needs of humanity inthe global village. ... Read more

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Thrombotic disease is a major cause of death and disablement in Western society. The most common cause is an inherited defect in one of the many genes encoding a protein which is involved in clotting, its regulation or the process of clot dissolution, fibrinolysis.
Venous Thrombosis: From Genes to Clinical Medicine presents our current knowledge of potential prothrombotic protein abnormalities, together with a clear and concise views of the roles these proteins play in haemostasis, and the use of molecular techniques in the analysis and diagnosis of inherited defects. Each chapter describes a specific protein deficiency, with information on protein structure, function and biochemistry, gene structure and expression, as well as epidemiological and molecular genetic aspects of the deficiency state.
This multi-faceted approach aims to examine the possible causes of venous thrombosis, to explain the underlying molecular defects and to explore the genotype-phenotype relationship in this complex multigene disorder. The potential roles of both epistatic interactions and environmental risk factors are also discussed. Venous Thrombosis: From Genes to Clinical Medicine will be of value to haematologists, genetic counselors, and clinical geneticists. ... Read more