1. NINDS Dermatomyositis Information Page Factsheet about the acquired muscle disease describes its onset, symptoms, treatments, and prognosis. Find selected references and organizations. Table of Contents (click to jump to sections). What is dermatomyositis? Is there any treatment? http://www.ninds.nih.gov/health_and_medical/disorders/dermato_doc.htm

National Institute of Neurological Disorders and Stroke Accessible version Science for the Brain The nation's leading supporter of biomedical research on disorders of the brain and nervous system Browse all disorders Browse all health organizations More about Dermatomyositis Studies with patients Research literature Press releases Search NINDS... (help) Contact us My privacy NINDS is part of the National Institutes of Health NINDS Dermatomyositis Information Page Reviewed 11-08-2001 Get Web page suited for printing Email this to a friend or colleague Table of Contents (click to jump to sections) What is Dermatomyositis? Is there any treatment? What is the prognosis? What research is being done? ... Related NINDS Publications and Information What is Dermatomyositis? Is there any treatment? Treatment for dermatomyositis generally consists of a steroid drug called prednisone. For patients in whom prednisone is not effective, other immunosuppressants such as azathioprine and methotrexate may be prescribed. Recently, a drug called intravenous immunoglobulin was shown to be effective and safe in the treatment of the disease. Physical therapy is usually recommended to preserve muscle function and avoid muscle atrophy. What is the prognosis?

2. Dermatomyositis (PM/DM) | MDA dermatomyositis (DM) Click for Materials En Español and MDAchats Bookmark this page! It's your source for information and news about PM/DM and will be updated regularly. Quick Definition Onset · Childhood to late adulthood. Symptoms · Weakness http://www.mdausa.org/disease/pmdm-d.html

Dermatomyositis (DM) Click for and MDAchats Bookmark this page! It's your source for information and news about PM/DM and will be updated regularly. Quick Definition: Childhood to late adulthood. Weakness of neck and limb muscles. Muscle pain and swelling common. Skin rash typically affecting cheeks, eyelids, neck, chest and limbs. Disease progression and severity vary among individuals. Often responds to drug therapy. Find Your Local MDA Do you need to find MDA in your city? Enter your Zip code here for where to turn for clinics and medical services; support groups; summer camp; local events and volunteer and fund-raising opportunities close to home. For more articles and references, please use the search feature Basic References FAQ's and Simply Stated Articles Quest Research-Medical Related ... News Releases Basic References Facts About PM/DM "Ask the Experts" Responses about PM/DM "Ask the Experts" Responses to General Neuromuscular Questions Genetics and Neuromuscular Diseases ... General Interest Publications FAQ's and Simply Stated... Articles FAQ: About Creatine Creatine Update: MDA Experts Say, 'Take Supplements Only Under Doctor's Care'

3. Allergy/Immunology - Juvenile Dermatomyositis JUVENILE dermatomyositis. There is no clear gender predominance in juveniledermatomyositis, whereas the adult form occurs more often in females. http://www.mc.vanderbilt.edu/peds/pidl/allergy/dermato.htm&e=42

4. Jordan's Juvenile Dermatomyositis Diary The diary of a 10 year old girl diagnosed with this rare disease including her treatment and progress. http://www.geocities.com/EnchantedForest/Meadow/6709/

Hello. My name is Sherrell and I am the mother of three loving children. My youngest child is a beautiful little girl named Jordan. She was only 10 years old, in 1998, when diagnosed with a rare disease called Juvenile Dermatomyositis. (JDMS) It is so rare, information is hard to come by. I thought I would put her diary on the Internet in hopes of getting more information and also, to let other parents, facing this same nightmare, know that they are not alone. The first months of the diary may be hard to read. It brings tears to my eyes and I wrote it and lived it. But, trust me, there are joyful tears in the months to come. We have been blessed, for God is taking care of our baby. We hope that the information is helpful to each of you. The diary is our personal experience and doesn't necessarily apply to everyone. However, if you share the diary with someone else that has been diagnosed with JDMS or is the parent of a child with JDMS, please encourage them to read the whole diary or at least through December 1998. I just recently found a forum that can connect us and may help answer many questions. You may want to check it out.

5. NINDS Dermatomyositis Information Page Information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke.Category Health Conditions and Diseases Auto-Immune Myositis...... More about dermatomyositis, Studies with patients, NINDS is part of the National Institutesof Health. NINDS dermatomyositis Information Page Reviewed 1108-2001 http://www.ninds.nih.gov/health_and_medical/disorders/dermato_doc.htm&e=42

6. Dermatomyositis Kurze œbersicht ¼ber die dermatomyositis und ihre Behandlung mit einer Liste von Kontaktpersonen f¼r diese seltene Erkrankung. http://www.dermatomyositis.de/

7. Dermatomyositis (PM/DM) MDA Background and references, provided by the Muscular Dystrophy Association.Category Health Conditions and Diseases AutoImmune Myositis......dermatomyositis (DM) Click for Materials En Español and MDAchats.Bookmark this page! It's your source for information and news http://www.mdausa.org/disease/pmdm-d.html&e=42

8. Juvenile Rheumatic Disease Group Website Online support for parents of children with a JRD, including juvenile rheumatoid arthritis, juvenile scleroderma, juvenile dermatomyositis, juvenile systemic lupus, and other rheumatic disorders. Includes resources. http://www.geocities.com/beegal68/JRD-Website.html

Welcome to the Juvenile Rheumatic Disease (JRD) Website ~Click the picture above to enter~ Graphic's provided by www.graphicgarden.com You are visitor number since October 2001 A Free Online Support Group Script's provided by Dynamic Drive This page was created with the help of the Meta Tag Analyzer Please, help save a child's life and read the above "Amber Alert". If you would like an Amber Alert ticker for your website, please, click the ticker!

9. Facts About Polymyositis And Dermatomyositis | MDA Publications Severe cases of this inflammation of the skin and muscles may cause enough atrophy to require use of a wheelchair. Read about research efforts. http://www.mdausa.org/publications/fa-myosi.html

Facts About Polymyositis and Dermatomyositis (PM/DM) Muscular Dystrophy Association Introduction Letter from Maureen McGovern Questions and Answers The Immune System ... MDA's Search for a Cause, Treatment and Cure INTRODUCTION Polymyositis and dermatomyositis are related diseases, both involving inflammation swelling or irritation of the voluntary muscles, those that normally govern movement, such as the muscles of the arms and legs. Myositis means inflammation of muscle. Polymyositis means inflammation of many muscles, and dermatomyositis means inflammation of muscle and skin. The results of either condition are weakened muscles and often muscle pain. These conditions are seldom fatal, but in the most severe cases a person may need a wheelchair or require assistance with activities of daily living. As early as 1863, a disease involving muscle inflammation and a reddish rash on the face and upper body was described and given the name polymyositis. In 1887, an apparent case of polymyositis without any rash was described by the German physician P. Hepp. Another German, H. Unverricht, then proposed using the name dermatomyositis for cases of muscle inflammation with skin changes and polymyositis for those without them. This terminology remains in use today. Both conditions are among the 40 neuromuscular diseases in the Muscular Dystrophy Association's program.

10. Facts About Polymyositis And Dermatomyositis MDA Publications Facts About Polymyositis and dermatomyositis(PM/DM) Muscular Dystrophy Association http://www.mdausa.org/publications/fa-myosi.html&e=42

11. The Myositis Support Group UK Information for sufferers and carers about dermatomyositis and Polymyositis related illnesses which affect the muscles and connective tissues of the body. http://dspace.dial.pipex.com/town/avenue/ye72/

Updated 15th March 2003 Myositis Support Group Chat on our Bulletin Board ..........Find out if there are others in your area with Myositis (see Buddies)....................... NEW The UK Myositis Support Group needs you. Click here now to find out why. NEW Myositis Support Group Conference and AGM Click here to find out more and register. NEW The December 2002 Newsletter is on line now. Click here to view. We now have 63 people registered on the 'Buddies' map. Why don't you add your name now ! WHAT IS MYOSITIS? Myositis literally means 'inflammation of the muscles'. This term covers a number of related illnesses including Dermatomyositis, Polymyositis, Juvenile Dermatomyositis and Inclusion Body Myositis. These diseases fall under the classification of 'Autoimmune' diseases, in that they are the result of abnormal immune responses (which the body would normally use to fight off diseases) attacking normal tissues - in this instance, the muscles. Thankfully these diseases are very rare, and to date, no-one really knows what causes them. As these diseases affect the muscles and connective tissues of the body, the main symptom is muscular weakness, which may be progressive and can be severely disabling, affecting in the majority of cases the whole body. People of any age and sex can develop 'Myositis', and depression and a general feeling of misery can frequently ensue. These diseases are not catching and there is no way to predict who may become affected. They can usually be suppressed by drugs which often have side effects which can promote worrying problems of their own. As yet there is no true cure for the disease, but many sufferers can go into partial or complete remission. Many sufferers need physiotherapy to prevent muscle shrinkage and to keep them mobile. Some fortunately do get better, but for the majority it is a case of coping with the disease and trying to live as near a normal life as possible. Some less fortunate do need a wheelchair from time to time while the disease is at its height.

12. More On Dermatomyositis dieser InternetSeite ein Forum für die Erkrankung dermatomyositis bieten. Ein wesentlicher Beweggrund für mich, http://www.dogpatch.org/sheltie/morederm.html

More on Dermatomyositis Here's some more info from Kim Schive ( KSchive@aol.com Dermatomyositis (DM), AKA sheltie skin syndrome, is a skin-and-muscle disorder that is known to affect collies (both varieties) and shelties, but is not generally seen in any other breed. Most of the research on canine DM (several varieties also occur in humans) has been done on collies, but it is likely that we are dealing with the same entity in both collies and shelties, so that research is relevant. The mode of inheritance appears to be autosomal dominant with variable expression. "Autosomal" means it is non-sex-linked, and occurs with equal frequency in males and females. "Dominant" means that one parent must HAVE IT to pass it on to offspring (or, possibly, it can occur as a new mutation; however, while possible, I believe this is highly unlikely, because if new mutations occured in canines, DM would be a problem in almost every breed). "Variable expression" means that disease severity can vary from very mildtoo mild to be diagnosedto very severe. Because the gene is dominant, there is no such thing as a "carrier." A dog either HAS it, or he doesn'twhether or not he gets diagnosed is the sticky part of the equation (see next paragraph). Affected dogs may have one gene for the disorder (D) and one normal gene (d). Such a dog would be referred to as heterozygous, and his genetic make-up would be Dd. Or, an affected dog may have two genes for the disorder (having inherited one from each parent). That dog would be referred to as homozygous, and his genetic make-up would be DD. It is probable that the more severely affected dogs are homozygous (DD), but nobody knows for sure.

13. Derm dermatomyositis. This information is provided as a public serviceand no warranty is expressed or implied. what is dermatomyositis? http://www.goldscout.com/derm.html&e=42

14. RalphB.net - Ralph Becker And His Stuff On The Web Offers information on Ralph's life, ISDN tutorial, FAQ for Toyota RAV4, description of Volkswagen Passat, and Juvenile dermatomyositis (JDMS) information. http://www.ralphb.net/

Julia's JDMS Diary ISDN Tutorial IP Subnetting Tutorial Toyota RAV4 FAQ ... ICQ / AIM: RalphB39, RalphB40 / EMail: or Feedback Form / WWW Service by WestHost accesses since July 7, 1999.

15. Dermatomyositis a CHORUS notecard document about dermatomyositis Disclaimer. Feedback. Search. dermatomyositis. sheets of calcification in soft tissues http://chorus.rad.mcw.edu/doc/00617.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system Feedback Search dermatomyositis sheets of calcification in soft tissues tumors in 15%: stomach, breast, lung, ovary Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 14 March 2001 Medical College of Wisconsin

16. Dermatomyositis http://www.dermatomyositis.de/&e=42

17. Chronische Inflammatoire Bindweefselziekten: Lupus Erythematosus, Sclerodermie, Lupus erythematosus, sclerodermie, polymyositis, dermatomyositis, Sjogrensyndroom, vasculitis, MCTD. http://www.CIBliga.com/

Lupus Sclerodermie Poly-en Dermatomyositis Vasculitis ... MCTD [CIB] [CIB-liga] [Contact] Chronische Inflammatoire Bindweefselziekten-liga A. Giraudstraat 10, 3000 Leuven Tel / Fax (016) 23 79 30 na 19 uur Zoek op deze site! Wat is er nieuw op de site? Laatste update: 27/03/03 Bekijk de statistieken van deze site! Webdesign door Twixel Starter Wat zijn chronische inflammatoire bindweefselziekten? Hier vind je een korte, duidelijke uitleg Aanrader Ga direct naar de databank met medische en andere artikels over chronische inflammatoire bindweefselziekten. Forum Op zoek naar lotgenoten? Heb je een prangende vraag? Bezoek ons Forum! Vervolgverhaal Lees de aflevering van ons vervolgverhaal "Doorgaan Frieda, vooral doorgaan"

18. Effective Intervention [Apr 1994; 3-3] Washington Univ School of Medicine in Missouri presents slides of muscle fibers affected by this autoimmune condition. Note the atrophy. dermatomyositis Childhood. Capillary pathology. Complement deposition. Inflammation Perivascular Perimysial http://www.jr2.ox.ac.uk/Bandolier/band3/b3-3.html

Bandolier Bandolier Library search Effective Intervention Background Dermatomyositis occurs infrequently, with an incidence probably less than 1 per 300,000 per year. It is characterised by an intramuscular microangiopathy mediated by a complement membrane attack complex. There is a loss of muscle capillaries, muscle ischaemia, muscle-fibre necrosis and perifascicular atrophy. There is an unmistakable rash with purplish appearance on the eyelids, cheeks and light exposed areas. A rash is often seen on the extensor surfaces of knees, elbows and knuckles, and this becomes scaly. Treatment is usually with steroids, but cytotoxic drugs and immunosuppressants are also added. Many patients do not respond to this treatment and remain physically disabled. RCT shows startling results A very well conducted double-blind placebo-controlled randomised control trial of high dose immune globulin has shown that it is an effective treatment. The study from the NIH in Bethesda looked at fifteen patients with therapy resistant dermatomyositis. Patients were block randomised to immune globulin infusion or placebo by disease severity, and they continued on their normal therapy during the study. Immune globulin was infused at 2g/kg body weight, with one infusion each month. Treatment was for three months, followed by cross-over after a one month washout. Patients were followed for three months after the end of the study before codes were broken.

19. Effective Intervention [Apr 1994; 3-3] Bandolier Library. search. Effective Intervention. Background. dermatomyositis occursinfrequently, with an incidence probably less than 1 per 300,000 per year. http://www.jr2.ox.ac.uk/bandolier/band3/b3-3.html&e=42

20. Juvenile Dermatomyositis - Julia's JDMS Diary Page How one family is dealing with this rare autoimmune disease that affects the muscles and skin. http://www.ralphb.net/JDMS/

About Julia FAQ JDMS Links Prayers ... Dec juvenile dermatomyositis, JDMS, pediatric, Julia, diary, myositis, skin rash, muscle weakness, muscle inflammation, prednisone, methotrexate, ivig, solu-medrol Juvenile Dermatomyositis (JDMS) is a rare childhood auto-immune disease. My daughter, Julia, was diagnosed with JDMS in March of 1998. This web site is here for two primary reasons. First, to chronicle the events surrounding Julia's diagnosis and treatment of Juvenile Dermatomyositis, thereby helping me cope with it. Second, to give other children and their parents in the same situation some much-needed information and support. Juvenile Dermatomyositis is a very rare disease; I have scoured the internet, bookstores, and libraries and there is precious little on JDMS to be found, and much of that is out of date. I hope that this site will be valuable to you as you learn to cope with it. I'm not a medical professional, so nothing you find here should be considered medical advice. If you have any questions, please start by visiting the Frequently Asked Questions . If you have feedback or comments, my email address is

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