41. The Insulin Resistance Syndrome And The Pathophysiology Of Hypertension, Cardiov The insulin resistance Syndrome and the Pathophysiology of Hypertension,Cardiovascular, and Renal Disease. This oneday workshop http://www.americanheart.org/presenter.jhtml?identifier=3007921

42. Insulin Resistance insulin resistance. insulin resistance occurs when insulin is less active than itshould be, or when cells are for some reason unable to respond to insulin. http://www.tufts.edu/med/nutrition_HIV/issues/insulin.html

Home Research Studies Health Issues Newsletter ... HIV Links Insulin Resistance What is it? Insulin, a hormone, regulates the transport of sugar from the blood into cells for use as fuel. Insulin resistance occurs when insulin is less active than it should be, or when cells are for some reason unable to respond to insulin. This leaves higher than normal levels of sugar circulating in the blood, which can lead to diabetes and many other health problems. Physicians and researchers are seeing an increase in cases of insulin resistance in their HIV-positive patients, particularly those taking protease inhibitor medications, and are working to find out why. Insulin resistance may also contribute to lipodystrophy Research Studies at Tufts Here in the Nutrition/Infection Unit at Tufts University School of Medicine, we are conducting studies looking at how treatment with metformin (

43. Wine Notes & Links: Provocative Reading For The Wine Enthusiast, Including Revie MODERATE DRINKING MAY PROTECT HEART BY IMPROVING insulin resistance.A partial answer to the question of how moderate drinking helps http://www.wineevents-calendar.com/notes/heart.html

Wine Tastings Professional Training Wine Ratings Competitions WINE CLASSIFIEDS Wine Merchants Wineries Private Party Wine Sales Wine Paraphernalia Sales ... Winemaking Equipment Book Store Winery Of The Year! Publishers' Wine Notes A Note on Wine Descriptors Exceptional '68-'70 Cabs Chards of '70-still alive Worthwhile Reading Rudd (CIA) Wine School Opens Indiana Constitutional challenge Wine shipping laws changed Congressional Wine Caucus ... Washington State report Health Research White wine helps lungs Improved insulin resistance Healthy lifestyle reports Source for research papers Recommended Books A Great Zin book "Burgundy" Update New Global Encyclopedia Publications Just-drinks.com Michigan travel planner Connoisseurs' Guide Grape Grower Miscellany Recipes from Quady Talk Show on cable radio COPIA Consorzio Cal-Italia ... U.S. wineries links Recommended Sites WineReader.com Professional Friends of Wine Top 100 Wine Sites Chef 2 Chef MODERATE DRINKING MAY PROTECT HEART BY IMPROVING INSULIN RESISTANCE A partial answer to the question of how moderate drinking helps to protect against coronary heart disease may be found in a University at Buffalo study linking alcohol consumption with improved insulin sensitivity.

44. Insulin Resistance: Implications For Metabolic And Cardiovascular Diseases Direct questions or comments to CME@webmd.net. insulin resistance Implicationsfor Metabolic and Cardiovascular Diseases CME Chairperson http://www.medscape.com/viewprogram/144

Focus On... ADHD ALLHAT Alzheimer's Disease Anthrax Asthma Biologic Therapies Bipolar Disorder Breast Cancer Depression Erectile Dysfunction Genital Herpes GERD Geriatric Care Heart Failure Heart Failure: CRT Hepatitis C HIPAA Home Defib in SCA Hyperlipidemia IBS InfluenZone Insulin Pump Tx Kidney Disease Menopause Micro Complications Multiple Sclerosis Osteoporosis Ovarian Cancer Pain Management Pancreatic Cancer Patient Safety Rheum Arthritis Schizophrenia Secondary Anemia Serious Mental Ill Sports Medicine UTI-Zone Weight Management Related Topics Health Diversity Hospice Care Medical Privacy Welcome, March 31, 2003 These educational activities, certified by accredited providers, were not prepared by Medscape's editors, but are made available on our site as a service to our audience. Authors are routinely instructed by the provider to disclose significant financial relationships and mention of investigational drugs and unapproved indications. Medscape has received a fee for posting these activities. Direct questions or comments to: CME@webmd.net

45. Page Error Decreased circulating levels of adiponectin, but not leptin levels, are associatedwith the insulin resistance seen with the loss of peripheral fat in patients http://www.medscape.com/viewarticle/447610

Focus On... ADHD ALLHAT Alzheimer's Disease Anthrax Asthma Biologic Therapies Bipolar Disorder Breast Cancer Depression Erectile Dysfunction Genital Herpes GERD Geriatric Care Heart Failure Heart Failure: CRT Hepatitis C HIPAA Home Defib in SCA Hyperlipidemia IBS InfluenZone Insulin Pump Tx Kidney Disease Menopause Micro Complications Multiple Sclerosis Osteoporosis Ovarian Cancer Pain Management Pancreatic Cancer Patient Safety Rheum Arthritis Schizophrenia Secondary Anemia Serious Mental Ill Sports Medicine UTI-Zone Weight Management Related Topics Health Diversity Hospice Care Medical Privacy Welcome, March 31, 2003 Page Error The article you requested can not be found. Please be advised that if you are trying to access an article from Reuters Health news wire, those articles expire after 30 days on our site. After that time, they can no longer be displayed. If the article you are trying to access is not from Reuters, please let us know by contacting medscapetechsupport@webmd.net Back Back to Your Homepage Advanced Search Medscape DrugInfo MEDLINE About Medscape Help WebMD Health

46. The Insulin Resistance Syndrome  Except From The insulin resistance Syndrome Excerpt from The insulin resistance Syndrome Abnormalitiesin glucose and lipid (blood fats) metabolism, obesity, and high http://www.netromall.com/guai-support/sf/InsulinResistanceSyndrome.htm

Original (tm) (est, October 1997) A trademark of Guai-Support The Guai-Support Network is a non-profit enterprise, provided to facilitate access to 'self-help' health education and support. To Support Tesa's daily goal to see that all Guai'ers are helped please click here The Insulin Resistance Syndrome Click on the underlined links for full articles FitDay Diet - Fitness Journal Low-Carb Cooking (shopping, web sites, books, etc.) Excerpt from Knight Ridder/tribune Originally published January 26, 2003, AKRON, Ohio : " Syndrome X boosts insulin level, causing obesity physician says. Medicine, low-carb diet help patients get control. "It's a condition called Syndrome X and it affects almost 70 million (one in four) Americans" "For people with Syndrome X, the invisible opponent is insulin, a hormone manufactured by the pancreas that is supposed to regulate glucose (blood sugars) and help the body use the glucose as energy. In Syndrome X, though, the cells that normally respond to insulin are resistant." "Once diagnosed, Syndrome X patients are put on a high-protein, low-carbohydrate diet, with medications - metformin (Glucophage) to increase the body's sensitivity to insulin and wellbutrin (Zyban) to help curb carbohydrate cravings"

47. Insulin Resistance Syndrome insulin resistance Syndrome. What is insulin resistance syndrome? Insulinis a kind of hormone. How do I know I have insulin resistance syndrome? http://familydoctor.org/handouts/660.html

Information from Your Family Doctor Insulin Resistance Syndrome What is insulin resistance syndrome? Insulin is a kind of hormone. It helps your body use the sugar in the food you eat as fuel. In some people, the tissues stop responding to insulin. Doctors refer to this condition as insulin resistance. If you have insulin resistance, your body will make more and more insulin, but because the tissues don't respond to it, your body won't be able to use sugar properly. Insulin resistance often goes along with other health problems, such as diabetes, high cholesterol, high blood pressure and heart attack. When a person has many of these problems together, doctors call it insulin resistance syndrome. How do I know I have insulin resistance syndrome? No simple test can tell that you have insulin resistance syndrome. If one or more of the following is true for you, your doctor may suspect you have insulin resistance syndrome. How to check your waist-to-hip ratio To find your waist-to-hip ratio, measure the smallest part of your waist with a tape measure. Don't hold in your stomach while you measure! Now measure the biggest part of your hips with a tape measure. Measure the part where your buttocks stick out the most.

48. Find Diabetes And Insulin Resistance Info And Details About A For more information on diabetes and insulin resistance visit avandia.com. IsAvandia Right for You? Avandia and insulin resistance. What Is Avandia? http://www.avandia.com/global/site_index.jsp

49. ICGGRI - Biological Atlas Of Insulin Resistance Biological Atlas of insulin resistance. Imperial College London ImperialCollege London is highly rated as one of the world class http://www.icggri.ic.ac.uk/bair.htm

Vision Background Training Governance ... Biological Atlas of Insulin Resistance Biological Atlas of Insulin Resistance Imperial College London Imperial College London is highly rated as one of the world class university institution for the quality of both their teaching and research. Imperial embodies and delivers world class scholarship, education and research for almost a century to produce science which enriches the fabric of society and innovation which feeds the successful industry. Imperial is uniquely positioned to explore the interfaces between science, medicine and engineering and deliver practical innovations for quality of life and the environment with particular regard to industry and healthcare. Background of Research Project Imperial College London, in conjunction with Queen Mary and Westfield College London, Cambridge University and Oxford University has been awarded a £5.4 million collaborative program grant funded by the Wellcome Trust Functional Genomics Development Initiative. The programme will evaluate the major unresolved questions concerning the molecular basis of insulin action and insulin resistance using existing a novel functional genomic strategies. The diseases associated with insulin resistance (type 2 diabetes, hypertension, hyperlipidaemia, obesity and coronary heart disease) represent dominant quarters of premature death and disability. Resources and analytical tools available through the genome project make a systematic molecular description of normal and disordered insulin action an achievable goal. The programme designated a

50. Abnormalities Of Glucose Metabolism, Including Insulin Resistance Abnormalities of Glucose Metabolism, Including insulin resistanceMichael Dube, MD, University of Indiana and ACTG researcher. The http://www.natap.org/lipod/110201_1.htm

Articles Back Abnormalities of Glucose Metabolism, Including Insulin Resistance Michael Dube, MD, University of Indiana and ACTG researcher The 3rd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV included some important new insights into the mechanisms behind insulin resistance in ARV drug-treated patients with HIV. There is an increasing recognition that there are 2 important factors contributing to the insulin resistance seen among treated patients, that due to the protease inhibitors and that due to fat redistribution itself. Both need to be considered in practice and in future research into potential interventions. Lesser progress has occurred with specific therapies that address insulin resistance, but insight into mechanisms is nonetheless very important into deciding what types of interventions are likely to be effective. (editorial comment: you can perform an insulin resistance test to evaluate whether or not you are developing insulin resistance, which can preceed seeing sugar elevations in the blood and diabetes. Performing the insulin resistance test is a way to perhaps identify a potential problem before sugar in your blood is elevated). In the Noor study a single 1200 mg oral dose of indinavir achieved standard steady plasma concentrations (10 uM) acutely reduced insulin stimulated glucose disposal by average of 34% in the 6 HIV-negative subjects. Although Haugaard reported not finding peripheral or hepatic insulin resistance associated with PI or NRTI, Yarasheski (abstract 6) reported HIV associated glucose intolerance is characterized by a greater duration of HIV perhaps meaning a greater duration to antiretroviral therapy).

51. Insulin Resistance, Glucose Intolerance: What Does It All Mean? insulin resistance, Glucose Intolerance What does it all mean? Will individualswith insulin resistance go on to develop Diabetes mellitus (DM). http://www.natap.org/2002/9retro/day35.htm

Conference Reports for NATAP 9th Conference on Retroviruses and Opportunistic Infections Seattle, Washington, February, 2002 Back Insulin Resistance, Glucose Intolerance: What does it all mean? Written for NATAP by Judith Aberg, Washington University, St Louis Dr. Currier and colleagues (Abstract 677-T) examined Medi-Cal (California Medicaid) claims from July 1994 to June 2000 for DM incidence rates in men and women over age 18 with and without HIV diagnoses. A total of 7219 (61% male) individuals with HIV and 2,792,971 (30% male) individuals without HIV were studied. A total of 7,101,180 person-years were examined. To assess only incident cases of DM diagnoses, individuals had to be free of DM related diagnoses and oral anti-diabetic pharmacy claims for at least one year prior to study inclusion. HIV-infected persons were 3.32 times more likely to have diabetes in this study. Overall incidence of DM per 100 person-years in HIV infected individuals is 10.68 (95% CI 10.15-11.23) and 2.91 (95% CI 2.89-2.92) in non-HIV infected individuals, odds ratio 3.32 (p <0.0001). Age-specific relative risk for DM in individuals with HIV compared to those without HIV range from 7.74 (95% CI: 5.03, 11.91, p

52. Insulin Resistance Syndrome The insulin resistance syndrome (IRS) is a group of health risk factors that increasethe likelihood of heart disease, and perhaps other disorders, such as http://www.mycustompak.com/healthNotes/Concern/Insulin_Resistance_Syndrome.htm

Insulin Resistance Syndrome Also indexed as: Metabolic Syndrome, Syndrome X Introduction Checklist Symptoms Treatments ... References The insulin resistance syndrome (IRS) is a group of health risk factors that increase the likelihood of heart disease and perhaps other disorders, such as diabetes and some cancers The risk factors that make up IRS include insulin resistance, which refers to the reduced ability of the hormone insulin to control the processing of glucose by the body. Other major risk factors often associated with IRS include high blood sugar and high blood triglycerides cholesterol high blood pressure , and excessive body fat in the abdominal region. People with IRS do not always have every one of these risk factors, but they usually have many of them. A qualified doctor should make the diagnosis of IRS after a thorough examination and blood tests. Most people with type 2 diabetes have insulin resistance, but many more people who are not diabetic also have insulin resistance. Since insulin resistance itself often does not cause symptoms, these people may not be aware of their problem. Some authorities believe insulin resistance is partially inherited and partially due to lifestyle factors. In addition to the recommendations discussed below, people with IRS may benefit from some of the recommendations given for type 2

53. Insulin Resistance And The Carnivore Connection Hypothesis insulin resistance/part 1 high incidence of diabetes in former huntergatherersmay be due to insulin resistance, an adaptation to meat-based diets. http://www.beyondveg.com/billings-t/comp-anat/comp-anat-7k.shtml

(Comparative Anatomy and Physiology Brought Up to Datecontinued, Part 7K) Insulin Resistance: The Carnivore Connection Hypothesis of Miller and Colagiuri [1994] THE PROBLEM: Incidence of adult- onset diabetes varies depending on recency of a population's exposure to agriculture. This section is based on Miller and Colagiuri [1994]. The carnivore connection hypothesis they elucidate provides an explanation, based on evolution, of the following phenomenon: Populations that have a relatively "long" history of agriculture, e.g., those of European descent, have a relatively low incidence of NIDDM, that is, non- insulin- dependent diabetes mellitus, also known as adult- onset diabetes. Populations that adopted agriculture more recently or, in other words, discontinued the evolutionary hunter- gatherer diet more recently, have relatively higher incidence rates of NIDDM. In some former hunter- gatherer populations, incidence levels of NIDDM range from epidemic levels (Nauruans; the Pima tribe of the U.S.), to rates that are "only" several times that of Europeans. THE HYPOTHESIS: Overview The carnivore connection is a hypothesis that explains the above in terms of insulin resistance and partial adaptation to the high- carbohydrate diets introduced via agriculture. The major points of the hypothesis are as follows (from Miller and Colagiuri [1994

54. Insulin Resistance insulin resistance Diabetes. What is insulin, insulin resistance, diabetes? Insulin is a hormone that carries glucose (sugar) from http://www.studenthealth.ucla.edu/handoutsold/insulin.htm

Insulin is a hormone that carries glucose (sugar) from your blood into your cells so that it can be burned for energy. The pancreas produces insulin. Insulin resistance is a state in which your cells are not responding to insulin appropriately, so the sugar in your blood cannot get into your cells. To compensate, your pancreas pumps out more insulin to try to get the sugar out of your blood and into your cells. The hyperinsulinimia (high blood insulin) that results is able to maintain normal blood sugar levels and delay the onset of diabetes. Diabetes Type 1 diabetes is usually diagnosed in childhood and occurs when the pancreas stops producing insulin. Insulin injections are required for life. Type 2 diabetes is usually diagnosed in adulthood. It occurs when the cells stop responding to insulin (often due to insulin resistance), and the pancreas is unable to keep compensating by producing more and more insulin to maintain normal blood sugar levels. Is it bad to have high blood insulin levels? Yes!

55. Scientists Close In On Trigger Of Insulin Resistance April 15, 2002 Contact Emilio Williams Telephone 1410-502-3216 E-mail emilio@jhmi.eduScientists Close In On Trigger Of insulin resistance Extra sugar can http://www.jhintl.net/English/Media/PRTrigger of Insulin Resistance.asp

Latest News Noticias en Espa±ol Other Languages Find an Expert ... Contact Us Press Release April 15, 2002 Contact: Emilio Williams Telephone: 1-410-502-3216 E-mail: emilio@jhmi.edu Scientists Close In On Trigger Of Insulin Resistance Extra sugar can cause insulin resistance in cells. Now scientists have an explanation. In experiments with fat cells, Johns Hopkins scientists have discovered direct evidence that a build-up of sugar on proteins triggers insulin resistance, a key feature of most cases of diabetes. The results underscore the importance of glycosylation - attachment of a sugar to a protein as a way cells control proteins' activities, the scientists report in the April 16 issue of the Proceedings of the National Academy of Sciences. The scientists found that at least two proteins involved in passing along insulin's message were unlikely to work properly when coated in extra sugar. Type 2 diabetes, the most common form in adults, occurs when muscle, fat and other tissues stop responding to insulin's signals to mop up sugar from the blood. The resulting high blood sugar, if uncontrolled, can lead to blindness, amputation and death. Understanding sugar's precise influence on insulin's activity may help improve treatment and prevention, scientists hope. "Cells don't respond to insulin itself. Instead, a whole cascade of events, set in motion by insulin, eventually causes cells to take in sugar," explains Gerald Hart, Ph.D., professor and director of biological chemistry in the school's Institute for Basic Biomedical Sciences. "We now have an explanation of how sugar can affect these signals, and even a hypothesis for how high blood sugar could cause tissue damage in diabetes by improperly modifying proteins."

56. Insulin Resistance What is insulin resistance? insulin resistance occurs when the normal amount ofinsulin secreted by the pancreas is not able to unlock the door to cells. http://server3002.freeyellow.com/yadanac/IR.html

Matchmaker.com: Sign up now for a free trial. Date Smarter! Insulin Resistance (IR) Diabetes IR Links IR Books Recipes ... Contact Me What is Insulin Resistance? Insulin resistance occurs when the normal amount of insulin secreted by the pancreas is not able to unlock the door to cells. To maintain a normal blood glucose, the pancreas secretes additional insulin. In some cases (about 1/3 of the people with insulin resistance), when the body cells resist or do not respond to even high levels of insulin, glucose builds up in the blood resulting in high blood glucose or type 2 diabetes. Even people with diabetes who take oral medication or require insulin injections to control their blood glucose levels can have higher than normal blood insulin levels due to insulin resistance. This information is from A site on Stanford Edu . For more information go to their site. Another meaning of Insulin Resistance A basic metabolic abnormality underlying Type II Diabetes. Insulin Resistance describes reduced insulin sensitivity of cells the action of insulin. Additional conditions may be associated with Insulin Resistance, including cardiovascular disease, hyperinsulinemia, dyslipidemia, hypertention, abdominal obesity, and clotting abnormalities, among others. back to the top

57. Atkins Nutritionals: The Science Behind Atkins: Research Summaries: Weight Loss: The Science Behind Atkins Research Summaries Weight Loss insulin resistance, Obesity and Heart Disease Risk. http://atkinscenter.com/Archive/2002/11/19-142859.html

The Science Behind Atkins Research Summaries Weight Loss > Insulin Resistance, Obesity and Heart Disease Risk Insulin Resistance, Obesity and Heart Disease Risk Reference: McLaughlin, T., Abbasi, F., Kim, H.S., et al., "Relationship Between Insulin Resistance, Weight Loss, and Coronary Heart Disease Risk in Healthy, Obese Women," Metabolism, 50(7), 2001, pages 795-800. Summary: The following information is available at Pub Med and was not written by Atkins professionals. <.005). variables insulin calorie-restricted reduce (3) focus changed modulate indicate insulin-sensitive; insulin-sensitive who that: by w.b. effective (2) plasma day-long 2001 not a women saunders vary function (1) dramatic as attempts insulin-resistant insulin-resistant, insulin-resistant. weight (p obese these none company Commentary: Commentary not available Back to top Prevalence of Impaired Glucose Tolerance Among Children and Adolescents With Marked Obesity High Insulin Levels and the Metabolic Syndrome Increased Dietary Protein Improves Blood Sugar and Insulin Levels During Weight Loss ... Evolutionary Aspects of Insulin Resistance For more information, e-mail us or call 1-800-2-ATKINS Home Why Atkins Works How to Do Atkins My Atkins ... Sitemap

58. Atkins Nutritionals: The Science Behind Atkins: Research Summaries: Cancer: Asso The Science Behind Atkins Research Summaries Cancer Associationof insulin resistance Syndrome and Colorectal Cancer. http://atkinscenter.com/Archive/2002/11/26-146648.html

The Science Behind Atkins Research Summaries Cancer > Association of Insulin Resistance Syndrome and Colorectal Cancer Association of Insulin Resistance Syndrome and Colorectal Cancer Reference: Colangelo, L.A., Gapstur, S.M., Gann, P.H., "Colorectal Cancer Mortality and Factors Related to the Insulin Resistance Syndrome," , 11(4), 2002, pages 385-391. Summary: The following information is available at Pub Med and was not written by Atkins professionals. Commentary: Commentary not available Back to top Dietary Sugar, Glycemic Load, and Pancreatic Cancer Risk Body Weight and Cancer Screening Among Women Is Obesity an Unrecognized Barrier to Preventive Cancer Care? ... Western Nutrition and the Insulin Resistance Syndrome: A Link to Breast Cancer For more information, e-mail us or call 1-800-2-ATKINS Home Why Atkins Works How to Do Atkins My Atkins ... Sitemap

59. Diabetes Forum:Eng_ Insulin Resistence 4. insulin resistance in associated with a member of clinical states. Syndrome associatedwith insulin resistance. 1. Genetic defects in insulin receptor. http://www.diabetesforum.net/eng_insulin_resist.htm

Basics Info Centre Case Studies Myths and Facts ... Site Map Special features select one News Letter Write your own articles Ask questions to doctor Forum 1. Insulin resistance refers to clinical condition in which the biologic response to insulin is diminished to below normal levels. 2. Clinically significant insulin resistance is usually identified when an adult patients requires more than 200 units of insulin a day or when a child requires more than 2.5 units/Kg of body weight. 3. The daily insulin output of adult pancreas is only between 20-50 units. 4. Insulin resistance in associated with a member of clinical states. Acute illness, surgery, infection and ketoacidosis can be accompanied by transient insulin resistance that increases the daily insulin requirements. Cushing’s disease, adrenal adenoma, ectopic ACTH syndrome and exogenous steriod use, acromegaly can cause insulin resistance. 5. Insulin resistance is invariably seen in the later stages of

60. Insulin Resistance Back Home Next. insulin resistance Ask the Doctor insulin resistance. Dr. AllenGale's IR Reference Information on insulin resistance, low-carbohydrate diets. http://www.ability.org.uk/Insulin_Resistance.html

Our Aims Services Stats ... Z Insulin Resistance Ask the Doctor: Insulin Resistance Dr. Allen Gale's IR Reference - Information on insulin resistance, low-carbohydrate diets. Glutamine and Human Enhancement The Glycemic Index: Flogging a Dead Horse? Insulin Resistance Insulin Resistance Information ... Webmaster . Site Design by Ability "see the ability, not the disability" Acknowledgments

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