21. Blood Platelet Disorders Blood platelet disorders. Back to previous level BernardSoulier SyndromeSearch PUBMED for Bernard-Soulier Syndrome All Review Therapy Diagnosis. http://www.ohsu.edu/cliniweb/C15/C15.378.140.html

Blood Platelet Disorders Back to previous level Bernard-Soulier Syndrome Search PUBMED for Bernard-Soulier Syndrome: All Review Therapy Diagnosis Platelet Storage Pool Deficiency Search PUBMED for Platelet Storage Pool Deficiency: All Review Therapy Diagnosis Thrombasthenia Search PUBMED for Thrombasthenia: All Review Therapy Diagnosis ... Thrombocytopenia [2 more specific term/s, 8 more link/s] Search PUBMED for Thrombocytopenia: All Review Therapy Diagnosis ... Thrombocytosis [1 more specific term/s, 1 more link/s] Search PUBMED for Thrombocytosis: All Review Therapy Diagnosis von Willebrand Disease Search PUBMED for von Willebrand Disease: All Review Therapy Diagnosis

22. Hematologic Diseases Search PUBMED for Blood Group Incompatibility All Review Therapy Diagnosis.Blood platelet disorders 6 more specific term/s, 5 more link/s http://www.ohsu.edu/cliniweb/C15/C15.378.html

Hematologic Diseases Back to previous level Anemia [9 more specific term/s, 24 more link/s] Search PUBMED for Anemia: All Review Therapy Diagnosis ... Blood Coagulation Disorders [11 more specific term/s, 8 more link/s] Search PUBMED for Blood Coagulation Disorders: All Review Therapy Diagnosis ... Blood Group Incompatibility [2 more specific term/s, 3 more link/s] Search PUBMED for Blood Group Incompatibility: All Review Therapy Diagnosis ... Blood Platelet Disorders [6 more specific term/s, 5 more link/s] Search PUBMED for Blood Platelet Disorders: All Review Therapy Diagnosis ... Blood Protein Disorders [9 more specific term/s, 6 more link/s] Search PUBMED for Blood Protein Disorders: All Review Therapy Diagnosis ... Bone Marrow Diseases [4 more specific term/s, 22 more link/s] Search PUBMED for Bone Marrow Diseases: All Review Therapy Diagnosis ... APLASTIC ANEMIA Erythrocyte Aggregation, Intravascular Search PUBMED for Erythrocyte Aggregation, Intravascular: All Review Therapy Diagnosis ... Hematologic Neoplasms [1 more specific term/s, more link/s] Search PUBMED for Hematologic Neoplasms: All Review Therapy Diagnosis ... Hemoglobinopathies [3 more specific term/s, 79 more link/s]

23. Platelet Disorders Home Back Up . platelet disorders platelet disorders, Inheritedplatelet dysfunction, See under Bleeding inherited bleeding disorders. http://www.rcpa.edu.au/pathman/platelet.htm

Platelet disorders Platelet disorders Quantitative See Thrombocytopenia and Thrombocytosis Qualitative Acquired platelet dysfunction Aspirin, other NSAID See under Bleeding - acquired bleeding disorders. Myeloproliferative disorders esp Essential Thrombocythaemia Myelofibrosis Paraproteinaemia Renal failure Inherited platelet dysfunction See under Bleeding - inherited bleeding disorders.

24. Guidelines For The Management Of Platelet Disorders Guidelines Guidelines for the Management of platelet disorders, http://peir.path.uab.edu/coag/article_223.shtml

Front Page Announcements Contact Us Clinical Conditions ... Test Order Form Search All Categories Front Page Announcements Contact Us Clinical Conditions Guidelines Links Patient Education Test Menu Test Order Form Guidelines Guidelines for the Management of Platelet Disorders Email this article Printer friendly page Platelet count Thrombocytopenia: single most common cause of bleeding ... Platelet concentrate therapy Platelet count /L /L Bleeding is unexpected, implies qualitative platelet disorder /L Bleeding may follow trauma, surgery, or dental extraction /L Spontaneous bleeding may require therapy [top] Thrombocytopenia: single most common cause of bleeding Marrow hypoplasia: chemotherapy, drug sequelae, ethanol Platelet consumption: acute and chronic immune thrombocytopenic purpura, drug-induced immune thrombocytopenia, neonatal alloimmune thrombocytopenia, post-transfusion purpura, thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome, DIC, HIT, and type 2B vWD [top] Thrombocytosis Reactive thrombocytosis: hemorrhage, surgery, iron deficiency anemia, inflammation Myeloproliferative disorders: essential thrombocytopenia, chronic myelogenous leukemia

25. Guidelines For The Management Of Platelet Disorders From UAB Coagulation Service (http//coag.path.uab.edu) GuidelinesGuidelines for the Management of platelet disorders. http://peir.path.uab.edu/coag/printer_223.shtml

From UAB Coagulation Service (http://coag.path.uab.edu) Guidelines Guidelines for the Management of Platelet Disorders Platelet count Thrombocytopenia: single most common cause of bleeding Thrombocytosis Platelet morphology ... Platelet concentrate therapy Platelet count /L /L Bleeding is unexpected, implies qualitative platelet disorder /L Bleeding may follow trauma, surgery, or dental extraction /L Spontaneous bleeding may require therapy [top] Thrombocytopenia: single most common cause of bleeding Marrow hypoplasia: chemotherapy, drug sequelae, ethanol Platelet consumption: acute and chronic immune thrombocytopenic purpura, drug-induced immune thrombocytopenia, neonatal alloimmune thrombocytopenia, post-transfusion purpura, thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome, DIC, HIT, and type 2B vWD [top] Thrombocytosis Reactive thrombocytosis: hemorrhage, surgery, iron deficiency anemia, inflammation Myeloproliferative disorders: essential thrombocytopenia, chronic myelogenous leukemia [top] Platelet morphology m m diameter Average normal diameter m m diameter Large physiologic platelets may indicate increased turnover with shortened marrow release time m m diameter Giant platelets imply myeloproliferative disorder, myelodysplastic syndrome, May-Hegglin anomaly

26. EMedicine - Platelet Disorders : Article By Perumal Thiagarajan, MD platelet disorders The hemostatic system consists of platelets, coagulation factors,and the endothelial cells lining the blood vessels. platelet disorders. http://www.emedicine.com/med/topic987.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Hematology Platelet Disorders Last Updated: February 6, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: autoimmune thrombocytopenia, alloimmune thrombocytopenia, drug-induced thrombocytopenia, thrombotic thrombocytopenic purpura, blood disorders, bleeding disorders, hematologic disorders, hemostatic disorders, clotting disorders, hemostatic plug, prolonged bleeding time, petechiae, purpura, immune thrombocytopenic purpura, ITP, TTP, posttransfusion purpura, post-transfusion purpura, neonatal alloimmune thrombocytopenia, hemolytic uremic syndrome, HUS, von Willebrand disease, vWD, Bernard-Soulier syndrome, Glanzmann thrombasthenia, diffuse intravascular coagulation, DIC AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Workup ... Bibliography Author: Perumal Thiagarajan, MD

27. Acquired Platelet Disorders Acquired disorders of platelet function. Acquired thrombopathias should be suspectedin animals with specific diseases and treated with certain drugs. http://web.vet.cornell.edu/public/popmed/clinpath/CPmodules/coags/acqplfun.htm

Acquired disorders of platelet function Acquired thrombopathias should be suspected in animals with specific diseases and treated with certain drugs. Platelets can have increased (resulting in thrombosis) or decreased function (resulting in hemorrhage) in these situations. The risk of bleeding is unpredictable and typically less severe and consistent than inherited disorders. Although abnormal platelet function occurs in these diseases, there may be other causes for the excessive hemorrhage seen in these conditions, such as thrombocytopenia. However, it should be recognised that platelets are not functioning normally in these situations and drugs that may exacerbate this should be avoided in these patients. Conditions in which there is decreased platelet function include neoplasia, monoclonal gammopathies, infectious disease, hepatic disease, renal disease, pancreatitis, DIC and immune-mediated thrombocytopenia. Neoplasia : In essential thrombocythemia and acute megakaryocytic leukemia, platelet aggregation and adhesion are defective. This can also occur in other neoplastic conditions, including chronic myeloid leukemia. Monoclonal gammopathy : Very high gamma globulin concentrations associated with some lymphoid or plasma cell neoplasms and atypical responses to some infectious diseases (e.g. Ehrlichiosis) can interfere sufficiently with platelet function

28. Acquired Platelet Disorders Acquired disorders of platelet number. Acquired disorders of plateletnumber include thrombocytopenia and thrombocytosis. Acquired http://web.vet.cornell.edu/public/popmed/clinpath/CPmodules/coags/acqpltno.htm

Acquired disorders of platelet number Acquired disorders of platelet number include thrombocytopenia and thrombocytosis. Acquired thrombocytopenia, usually immune-mediated, is the most common hemostatic disorder you will encounter in private veterinary practice. A platelet count should be performed on every animal presenting with clinical signs of hemorrhage. Thrombocytopenia Thrombocytosis

29. Disease Category Listing (121): Platelet Disorders Clinical Trials platelet disorders. There are no studies currentlylisted in this category on the CenterWatch web site. Back to http://www.centerwatch.com/studies/cat121.htm

Clinical Trials: Platelet Disorders There are no studies currently listed in this category on the CenterWatch web site. Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials. Trial listing updated: March 28, 2003 at 3:27:43 PM Patient Resources: [ Trial Listing Notification Services Drug Directories About Clinical Research ... Patient Bookstore Professional Resources: [ Research Center Profiles Industry Provider Profiles Industry News Professional Resources ... Professional Bookstore General: [ Search Site Map Your Privacy CW World ... Home This site was developed in association with Illumina Interactive of Boston, MA

30. Florida State University College Of Medicine Digital Library Clinical Resources by Topic Hematology. platelet disorders ClinicalResources. See also platelet disorders Patient/Family Resources. http://fsumed-dl.slis.ua.edu/clinical/hematology/bleedingdisorders/plateletdisor

Clinical Resources by Topic: Hematology Platelet Disorders Clinical Resources See also: Platelet Disorders Patient/Family Resources General Hematology Clinical Resources Platelet Disorders Clinical Resources by Sub-Topic: Acquired Platelet Dysfunction Myeloproliferative Disorders Thrombocytopenia von Willebrand Disease For additional Platelet Disorders Sub-Topics, go to General Hematology Clinical Resources Medical Library Florida State University College of Medicine Service provided by the Clinical Digital Libraries Project of the UA and UNT Schools of Library and Information Studies Powered by UA Digital Libraries Navigation Lab technology

31. Florida State University College Of Medicine Digital Library Patient/Family Resources by Topic Hematology. platelet disorders Patient/FamilyResources. See also platelet disorders Clinical Resources. http://fsumed-dl.slis.ua.edu/patientinfo/hematology/bleedingdisorders/plateletdi

Patient/Family Resources by Topic: Hematology Platelet Disorders Patient/Family Resources See also: Platelet Disorders Clinical Resources General Hematology Patient/Family Resources Platelet Disorders Patient/Family Resources by Sub-Topic: Acquired Platelet Dysfunction Myeloproliferative Disorders Thrombocytopenia von Willebrand Disease ... Florida State University College of Medicine Service provided by the Clinical Digital Libraries Project of the UA and UNT Schools of Library and Information Studies Powered by UA Digital Libraries Navigation Lab technology

32. Blood Platelet Disorders Marrow Transplantation. Blood platelet disorders. SUBCATEGORIES. UpThrombocytopenia. America Medica, Inc. ®. info@medlina.com. New York. http://www.medlina.com/blood_platelet_disorders.htm

Academic Medicine Addiction Aging AIDS-HIV ... Women's Health The Web MEDLINA.com (partial) CDC WHO FDA NIH CATEGORIES Search: All Products Books Magazines Popular Music Classical Music Video DVD Baby Electronics Software Outdoor Living Wireless Phones Keywords: Home Up Hematology Books Lymphatic System Disorders ... Neutropenia Blood Platelet Disorders Hematology Research Hematology Associations Blood Banks Blood Products ... Bone Marrow Transplantation Blood Platelet Disorders SUBCATEGORIES Up Thrombocytopenia powered by A merica M edica, I nc. info@medlina.com New York City

33. Platelet Disorders The excessive bleeding in platelet disorders is mucosal or affects the skin Plateletdisorders can be divided into Thrombocytopenia. Abnormal platelet function. http://www.mds.qmw.ac.uk/biomed/kb/resources/haematology/diseases/haemostasis/pl

Platelet Defects The excessive bleeding in platelet disorders is mucosal or affects the skin: Mucosa Skin Epistaxis Gastrointestinal Bleeding Menorrhagia Purpura Petechiae Ecchymoses Symptoms usually occur when the platelet count is /L but this may be higher when there is impaired platelet function. Platelet disorders can be divided into Thrombocytopenia Abnormal platelet function (Back to Haemostasis Index) Thrombocytopenia Causes Failure of Production Increased consumption Aplasia Drugs, chemicals or X-rays Viral infection e.g. hepatitis, parvovirus Bone marrow infiltration Toxic damage Vitamin B12 or Folic acid deficiency Congenital Immune thrombocytopenia Autoimmune or idiopathic thrombocytopenic purpura (ATP or ITP) Thrombotic thrombocytopenic purpura (TTP) Consumption coagulopathy (e.g. DIC Hypersplenism Post transfusion purpura (Back to Platelet Defects) Abnormal Platelet Function Causes Congenital Acquired Von Willebrands disease Bernard Soulier syndrome Glanzmann's thrombasthenia Storage pool disease Platelet release defect Aspirin Uraemia Hypergammaglobulinaemia Myeloproliferative disease (Back to Platelet Defects)

34. Diagnosis Of Inherited Platelet Disorders In 1998 - Hématologie Diagnosis of inherited platelet disorders in 1998. Hématologie. Vol. The explanationfor the development of giant platelet disorders remains an enigma. http://www.john-libbey-eurotext.fr/articles/hma/4/3/190-200/en-resum.htm

Diagnosis of inherited platelet disorders in 1998 Summary: Author(s): Paquita Nurden, Eric Cazes, Christine Vergnes, Alan T. Nurden Keywords: inherited disorders, platelets, aggregation, flow cytometry. © John Libbey Eurotext

35. Platelet Disorders - General Practice Notebook platelet disorders. The haemostasis. platelet disorders that may interferewith this mechanism are too few platelets thrombocytopaenia; http://www.gpnotebook.co.uk/cache/-1389035490.htm

platelet disorders The formation of the initial platelet plug is an important component of normal haemostasis. Platelet disorders that may interfere with this mechanism are: too few platelets - thrombocytopaenia abnormal platelet function - thrombocytopathy Thrombocytopaenia accounts for the majority of cases. Click here for more information...

36. Inherited Giant Platelet Disorders Julkaisu. Reference. Jantunen E. Inherited giant platelet disorders.Eur J Haematol 199453191196. Julkaisutiedot. Julkaisutyyppi http://www.uku.fi/wwwdata/julkaisutoiminta/julkaisut/1994/9400813.html

Julkaisu Reference Jantunen E. Inherited giant platelet disorders. Eur J Haematol Julkaisutiedot Julkaisutyyppi: Katsausartikkeli tiet.lehdessä. Kansainvälinen. Publication data Publication type: Review article, minireview. International. Tekijät Contributors Kuopion yliopisto Sisätautien klinikka University of Kuopio Department of Internal Medicine Julkaisutietokanta Publications Data Base

37. Platelet Disorders Resources On The Internet platelet disorders. Health News, Platelet Dysfunction A list of disorders associatedwith platelet dysfunction and drugs and their effects on platelets. http://www.healthcyclopedia.com/platelet_disorders.html

Home Health Conditions by Category ... Contact Us Platelet Disorders Health News Search millions of published articles for news on Platelet Disorders The eLibrary newspaper and magazine archive contains articles from current and back issues of hundreds of publications, including: Modern Medicine Aging The Ardell Wellness Report HealthFacts The Journal of Environmental Health Medical Post Medical Update Men's Health and the National Women's Health Report Note: To access the full text of articles, sign up for a seven-day no-risk free trial subscription to eLibrary. Web Directory Web Links: Acquired Bleeding Disorders - An article by Thomas G. DeLoughery, Associate Professor of Medicine. Platelet transfusion therapy and dysfunctional platelets are discussed. Adult Chronic Immune Thrombocytopenic Purpura - A guide for patients. A description of this disease followed by an in depth look. Idiopathic Thrombocytopenic Purpura - ITP: A look at what these words actually mean, what he causes are, who gets it, diagnosis, how it affects children and adults and pregnant women. Immune Thrombocytopenic Purpura - WebDoctor: Clinical presentation, cause and pathophysiology, evaluation of antiplatelet autoantibody, differential diagnosis and prognosis and treatment.

38. Thrombopoietin, Modes Of Action And Role In Platelet Disorders Thrombopoietin modes of action, role in platelet disorders new drug. AlbertEG.Kr. Role of Tpo in platelet disorders. Disorders with thrombocytopenia. http://www.slz.nl/hora/literatu/pages/1998/tpo.htm

Albert E.G.Kr. von dem Borne , Leendert Porcelijn , Claudia Folman , Sonja van den Oudenrijn , Gabor E Linthorst , C. Ellen van der Schoot , Masja de Haas 1 Department of Hematology, Division of Internal Medicine, Academic Medical Center, 2. Department of Hematology, Division of Medical Oncology, Anthonie van Leeuwenhoek Hospital/The Netherlands Cancer Institute, and 3. Department of Experimental Immunohematology, Central Laboratory of the Netherlands Red Cross Blood Transfusion Center Correspondence: Albert E.G.Kr. von dem Borne, Department of Hematology, Division of Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam; E-mail borne@amc.uva.nl Table of Contents Introduction Structural Information Thrombopoietin Tpo receptor (Tpo-R) ... Reference List Introduction Thrombopoietin (Tpo) is a haematopoietic growth factor that stimulates the development of megakaryocyte precursors, megakaryocytes and platelets. The existence of such a factor was already suggested in 1958 (Kelemen et al , 1958) and demonstrated in the early sixties by studies in rats (Odell et al , 1961). However, attempts to obtain thrombopoietin were unsuccessful in the years thereafter.

39. Hematology - Platelet Disorders Hematology. platelet disorders. Thrombasthenia. Defect in aggregation.Thrombocythemia, Thrombocytosis. Platelet count greater than 450,000 http://lifehealth.facworld.com/WTS/lifeonline/online/Hemato_50/HEM_Platelets.htm

Hematology Platelet Disorders Thrombasthenia Defect in aggregation Thrombocythemia, Thrombocytosis Platelet count greater than 450,000, reactive thrombocythemia, essential thrombocythemia; primary thrombocythemia Thrombocytopenia Platelet count less than 100,000

40. MEDLINEplus Medical Encyclopedia: Acquired Platelet Function Defect Alternative names Return to top Acquired qualitative platelet disorders;Acquired disorders of platelet function. Definition Return http://www.nlm.nih.gov/medlineplus/ency/article/000546.htm

Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Acquired platelet function defect Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Blood clot formation Blood clots Alternative names Return to top Acquired qualitative platelet disorders; Acquired disorders of platelet function Definition Return to top Non-hereditary diseases or associated conditions that cause the platelets (the blood cells essential for coagulation) to not function properly. Causes, incidence, and risk factors Return to top Platelets are blood cells that are essential for blood clotting. Platelet disorders can include inappropriate number of platelets (too many or too few), or normal number but inappropriate functioning of the platelets. Any platelet disorder affects blood clotting. Disorders of platelet function can be caused by congenital diseases or acquired conditions. Acquired platelet function disorders are disorders of inappropriate platelet function, and that develop as a result of another disease or condition (acquired). In many cases, the platelet count may be normal or even elevated, but evidence of a bleeding disorder will be present.

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