Health Ency.: Disease: Hypopituitarism hypopituitarism See images. In hypopituitarism, one or more pituitaryhormones may be lacking. Lack of the hormone leads to loss http://www.austin360.com/shared/health/adam/ency/article/000343.html
Extractions: Important notice Ency. home Disease H Hypopituitarism See images Overview Symptoms Treatment ... Prevention Alternative names: Pituitary insufficiency Definition: An abnormal condition caused by a deficiency of one or more hormones secreted by the pituitary gland. Causes and Risks The pituitary gland is a small structure that is located at the base of the brain. It is attached by a stalk to the hypothalamus , an area of the brain that controls the function of the pituitary gland. The hormones secreted by the pituitary and their functions are: growth hormone (GH), which stimulates growth of tissues and bone thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism adrenocorticotropic hormone (ACTH), which stimulates the adrenal gland to secrete hormones that affect metabolism prolactin , which stimulates female breast development and milk production luteinizing hormone (LH), which controls sexual function in males and females follicle stimulating hormone (FSH), which controls sexual function in males and females
Health Ency.: Disease: Hypopituitarism hypopituitarism See images. Treatment. If the hypopituitarism is caused by a tumor,treatment by surgical removal and/or radiation therapy may be indicated. http://www.austin360.com/shared/health/adam/ency/article/000343trt.html
Extractions: Important notice Ency. home Disease H Hypopituitarism See images Overview Symptoms Treatment ... Prevention Alternative names: Pituitary insufficiency Treatment If the hypopituitarism is caused by a tumor , treatment by surgical removal and/or radiation therapy may be indicated. However, replacement of deficient hormones is still often required even after successful treatment of a pituitary tumor. Hormone therapy is needed to replace hormones no longer made by organs under the control of the pituitary gland. These include corticosteroids (cortisol), thyroid hormone, sex hormones ( testosterone for men and estrogen for women), and growth hormone in children. Drugs are available to treat associated infertility in men and women. Prognosis Hypopituitarism is usually permanent and requires life-long treatment; however, a normal life span can be expected. Complications Side effects of drug therapy can develop. Call Your Health Care Provider If: Call your health care provider if symptoms of hypopituitarism develop. Ency. home
The Pituitary Foundation | GP Fact File | 6. Hypopituitarism 5. Hyperprolactinaemia . 6. hypopituitarism . 7. Craniopharyngioma . . AboutThe Pituitary Foundation . Pituitary Foundation Fact Sheet. hypopituitarism. http://www.pituitary.org.uk/gp-factfile/6-hypopit.shtml
Extractions: Fact Sheet Hormone deficiency caused by the inadequate secretion of one or more of the hormones normally secreted by the pituitary, is known as hypopituitarism. It may be caused by compression of the normal tissue by a developing tumour, surgery, or radiotherapy. If hypopituitarism is caused by tumour compression, function may be partially or fully recovered after surgery or medical therapy to reduce the size of the tumour. Surgically-induced hypopituitarism may occur in some cases, particularly if the tumour is large, but this can be transitory and some or all of the function may recover. Hypopituitarism may also develop after several years of treatment of a pituitary tumour by radiotherapy. Symptoms of Hormone Deficiency Symptoms Deficient Hormone Growth retardation in children, excessive tiredness, muscle weakness
Extractions: University of Birmingham The pituitary gland is the most important endocrine gland in the body, as it produces several important hormones. In turn, these hormones control most of the other hormone systems in the body. The hormones produced by the anterior pituitary include growth hormone (GH), thyroid stimulating hormone (TSH), adrenal stimulating hormone (also known as adrenocorticotrophic hormone or ACTH), luteinising hormone (LH) and follicle stimulating hormone (FSH) (also known as the gonad stimulating hormones or gonadotrophins) and prolactin (Prl). The posterior pituitary produces a hormone called vasopressin (also known as anti-diuretic hormone or ADH). The most common causes of hypopituitarism are tumours of, or close to, the pituitary. The vast majority of these tumours are non-functional i.e. the tumour itself does not produce any hormones, but tumours also occur that overproduce one of the other hormones produced by the pituitary e.g. prolactinoma. If these tumours compress and damage the normal pituitary tissue, the pituitary can no longer function normally and this results in deficiency of the pituitary hormones (hypopituitarism). The term panhypopituitarism refers to deficiency of all the pituitary hormones. Other causes of hypopituitarism include trauma (usually caused by a significant head injury), radiotherapy, pituitary infarction and very rare diseases or infections such as sarcodosis.
Hypopituitarism Anterior Pituitary Deficiency Syndromes. 90% of cases are caused bydestruction of the anterior pituitary. In general, more than 75 http://www.som.tulane.edu/classware/pathology/medical_pathology/pituitary/11hypo
Hypopituitarism First Previous Next Last Index Text. Slide 24 of 42. http://www.som.tulane.edu/classware/pathology/medical_pathology/New_for_99/endoc
Hypopituitarism hypopituitarism (PITUITARY DEFICIENCY). Associations between hypopituitarismand autism have been found (Gingell et al, 1996). Studies http://64.177.90.157/autism/html/hypopituitarism.html
Extractions: PITUITARY DEFICIENCY) Associations between hypopituitarism and autism have been found ( Gingell et al, 1996 Studies have shown abnormal pituitary hormone responses to neuroendocrine agonists in autistic subjects ( Realmuto et al, 1990 Occurrence of hypopituitarism in hypothyroidism has been documented, and found to be reversible with treatment. ( Fernandez-Real et al, 1998 Ikeda et al, 2000 see also:Dex Fernandez-Real JM, Ricart W, Porcar C, Teruel J - "Reversible hypophyseal disfunction and hyperplasia in two cases of primary hypothyroidism" Rev Clin Esp 198(1):28-32 (1998) Gingell K, Parmar R, Sungum-Paliwal S - "Autism and multiple pituitary deficiency" Dev Med Child Neurol 38(6):545-9 (1996) Ikeda K, Matsushita M, Ando S, Sekigawa I, Iida N, Hashimoto H - "A case of hypopituitarism and primary hypothyroidism associated with antiphospholipid syndrome" Nihon Rinsho Meneki Gakkai Kaishi 2000 Feb;23(1):37-42 (2000) Realmuto GM, Jensen JB, Reeve E, Garfinkel BD - "Growth hormone response to L-dopa and clonidine in autistic children" J Autism Dev Disord 20(4):455-65 (1990)
Hypopituitarism hypopituitarism hypopituitarism, Diagnosis and evaluation may involveassay of pituitary or target gland hormones. Dynamic stimulation http://www.rcpa.edu.au/pathman/hypopitu.htm
Extractions: Hypopituitarism Diagnosis and evaluation may involve assay of pituitary or target gland hormones. Dynamic stimulation tests may assist to evaluate hormone reserves: insulin hypoglycaemia stimulation test is usually sufficient; rarely, stimulation tests using gonadotrophin releasing hormones are occasionally of value - consult pathologist. Panhypopituitarism Patients may have clinical or radiological evidence of a space occupying lesion in the pituitary fossa. They may present initially with deficiency of a single hormone: prolactin testosterone (in males), LH FSH (in post-menopausal females), TSH thyroxine (free) , cortisol. Non-functioning tumours Adenoma Craniopharyngioma Meningioma Germinoma Metastatic carcinoma Functioning tumours eg Prolactinoma Gonadotroph adenoma Alpha subunit - this may be the main secretory product of the tumour. Hypothalamic disorders eg See also Pituitary/hypothalamic disorders Tumour Birth asphyxia Histiocytosis Vascular disorders eg Post-partum necrosis Post-traumatic Post-hypophysectomy Post-irradiation Septo-optic dysplasia Granulomas eg Sarcoidosis Tuberculosis Empty sella syndrome Genetic eg Familial panhypopituitarism Single hormone deficiency May be the presenting feature of any cause of panhypopituitarism, however single hormone deficiency can occur and is usually genetic.
Avera Health - Hypopituitarism hypopituitarism. Definition hypopituitarism is a condition caused by low levelsof pituitary hormones. Alternative Names Pituitary insufficiency. http://www.avera.org/adam/ency/article/000343.htm
Extractions: Causes, incidence, and risk factors: The pituitary gland is a small structure that is located just below the brain. It is attached by a stalk to the hypothalamus , the area of the brain that controls its function. The hormones secreted by the pituitary and their functions are: growth hormone (GH), which stimulates growth of tissues and bone thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism adrenocorticotropic hormone (ACTH), which stimulates the adrenal gland to secrete cortisol which helps to maintain blood pressure prolactin , which stimulates female breast development and milk production luteinizing hormone (LH), which controls sexual function in males and females follicle stimulating hormone (FSH), which controls sexual function in males and females antidiuretic hormone (ADH), which controls water loss by the kidneys
The Pituitary Society - Information For The Public hypopituitarism. by Mark E. Molitch, MD Northwestern University Medical School.Pituitary Hormones and Their Regulation. Causes of hypopituitarism. http://pituitarysociety.med.nyu.edu/molitch.htm
Extractions: THIS INFORMATION WAS DEVELOPED BY MARK E. MOLITCH, M.D. IT IS NOT INTENDED TO SUBSTITUTE FOR A FULL AND FRANK CONSULTATION WITH QUALIFIED MEDICAL PERSONNEL, WHICH IS THE PRIMARY MEANS FOR A PATIENT TO OBTAIN CARE AND TREATMENT. THE INFORMATION WAS BELIEVED TO BE CURRENT ON MAY 1, 2001, AND WITH THE LAPSE OF TIME, CERTAIN OF THIS MATERIAL WILL BE OUTDATED. Northwestern University Medical School Pituitary Hormones and Their Regulation Hypopituitarism refers to the condition in which one or more of the 6 pituitary hormones are deficient. Growth hormone GH , also known as somatotropin) is the hormone primarily responsible for growth in children but it may also play a role in adults in regulating fat and muscle tone. Prolactin PRL ) is the hormone primarily responsible for breast milk production after delivery in women; its roles outside of this function in women and in men are unknown. Adrenocorticotropic hormone ACTH ) is that hormone necessary to stimulate the adrenal gland to produce its hormones, cortisol and adrenal androgens, especially in times of stress.
Welcome To ENH.org - Health Encyclopedia: Hypopituitarism hypopituitarism. Definition hypopituitarism is a condition caused by low levelsof pituitary hormones. Alternative Names Pituitary insufficiency. http://www.enh.org/Encyclopedia/ency/article/000343.asp
Extractions: Causes, incidence, and risk factors: The pituitary gland is a small structure that is located just below the brain. It is attached by a stalk to the hypothalamus , the area of the brain that controls its function. The hormones secreted by the pituitary and their functions are: growth hormone (GH), which stimulates growth of tissues and bone thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism adrenocorticotropic hormone (ACTH), which stimulates the adrenal gland to secrete cortisol which helps to maintain blood pressure prolactin , which stimulates female breast development and milk production luteinizing hormone (LH), which controls sexual function in males and females follicle stimulating hormone (FSH), which controls sexual function in males and females antidiuretic hormone (ADH), which controls water loss by the kidneys
Hypopituitarism hypopituitarism. Patients diagnosed with hypopituitarism may be deficient inone single hormone, several hormones, or have complete pituitary failure. http://www.hendrickhealth.org/healthy/000722.htm
Extractions: Resources Hypopituitarism is loss of function in an endocrine gland due to failure of the pituitary gland to secrete hormones which stimulate that gland's function. The pituitary gland is located at the base of the brain. Patients diagnosed with hypopituitarism may be deficient in one single hormone, several hormones, or have complete pituitary failure. The pituitary is a pea-sized gland located at the base of the brain, and surrounded by bone. The hypothalamus, another endocrine organ in the brain, controls the function of the pituitary gland by providing "hormonal orders." In turn, the pituitary gland regulates the many hormones that control various functions and organs within the body. The posterior pituitary acts as a sort of storage area for the hypothalamus and passes on hormones that control function of the muscles and kidneys. The anterior pituitary produces its own hormones which help to regulate several endocrine functions. In hypopituitarism, something interferes with the production and release of these hormones, thus affecting the function of the target gland. Commonly affected hormones may include:
Hypopituitarism Endocrinology. hypopituitarism. What is hypopituitarism? hypopituitarism,also and dramatic. What are the symptoms of hypopituitarism? http://www.mcghealthcare.org/endocrinology/pithub/hypopit/hypopit.htm
Extractions: Hypopituitarism, also called an underactive pituitary gland, is a condition that affects the anterior lobe of the pituitary gland usually resulting in a partial or complete loss of functioning of that lobe. The resulting symptoms depend on which hormones are no longer being produced by the gland. Because the pituitary gland affects the other endocrine organs, effects of hypopituitarism may be gradual or sudden and dramatic. What are the symptoms of hypopituitarism? (luteinizing hormone and follicle-stimulating hormone) In premenopausal women, this leads to absent menstrual cycles, infertility, vaginal dryness, and loss of some female characteristics. In men, this deficiency leads to impotence, shriveling of testes, decreased sperm production, infertility, and loss of some male characteristics. insufficient growth hormone production There is currently a great deal of research concerning adult growth hormone deficiency. Whether it should be treated is not yet clear. In children, this deficiency can lead to stunted growth and dwarfism.
Extractions: PITUITARY TUMOR PROGRAM PITUITARY DIAGNOSES INDEX Hypopituitarism is a general term that refers to any underfunction of the pituitary gland. This is a clinical definition used by endocrinologists and is interpreted to mean that one or more functions of the pituitary are deficient. The term may refer to both anterior and posterior pituitary gland failure. Causes of hypopituitarism Deficiency of ACTH and cortisol Deficiency of ACTH resulting in cortisol deficiency is the most dangerous and life threatening of the hormonal deficiency syndromes. With gradual onset of deficiency over days or weeks, symptoms are often vague and may include weight loss, fatigue, weakness, depression, apathy, nausea, vomiting, anorexia and hyperpigmentation. As the deficiency becomes more serious or has a more rapid onset, (Addisonian crisis) symptoms may include confusion, stupor, psychosis, abnormal electrolytes (low serum sodium, elevated serum potassium), and vascular collapse (low blood pressure and shock) which can be fatal. Treatment consists of cortisol administration or another similar steroid (like prednisone) in a tightly regulated manner. For patients with acute adrenal insufficiency (Addisonian crisis), rapid intravenous administration of high dose steroids is essential to reverse the crisis. Deficiency of TSH and thyroid hormone Deficiency of thyroid hormone causes a syndrome consisting of decreased energy, increased need to sleep, intolerance of cold (inability to stay warm), dry skin, constipation, muscle aching and decreased mental functions. This constellation of symptoms is very uncomfortable and is often the symptom complex that drives patients with pituitary disease to seek medical attention. Replacement therapy consists of thyroxin (Syntroid), which is monitored by blood levels of thyroid hormone.
Hypopituitarism hypopituitarism. Back to previous level Diabetes Insipidus 2 morespecific term/s, 1 more link/s Search PUBMED for Diabetes Insipidus http://www.ohsu.edu/cliniweb/C19/C19.700.482.html
Hypopituitarism - Lucile Packard Children's Hospital Diabetes Other Endocrine and Metabolic Disorders. hypopituitarism Thiscondition is called panhypopituitarism. What is hypopituitarism? http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/diabetes/hypop.html
Extractions: Hypopituitarism, also called an underactive pituitary gland, is a condition that affects the anterior (front) lobe of the pituitary gland - usually resulting in a partial or complete loss of functioning of that lobe. The resulting symptoms depend on which hormones are no longer being produced by the gland. Because the pituitary gland affects the other endocrine organs, effects of hypopituitarism may be gradual, or sudden and dramatic. The symptoms of hypopituitarism vary depending on which hormones are insufficiently produced by the pituitary gland. In addition, the symptoms of hypopituitarism in children will vary depending on their age. Each child may also experience symptoms differently. The following are common symptoms associated with reduced production of certain hormones:
Extractions: Signs, symptoms and indicators Conditions that suggest it Contributing risk factors It can lead to... ... Recommendations Hypopituitarism is a general term that refers to any under-performance of the pituitary gland. This is a clinical definition used by endocrinologists and is interpreted to mean that one or more functions of the pituitary are deficient. The term may refer to both anterior and posterior pituitary gland failure. Deficient pituitary gland function can result from damage to either the pituitary or the area just above the pituitary, namely the hypothalamus . The hypothalamus contains releasing and inhibitory hormones that control the pituitary. Since these hormones are necessary for normal pituitary function, damage to the hypothalamus can also result in deficient pituitary gland function. Injury to the pituitary can occur from a variety of insults, including damage from an enlarging pituitary tumor, irradiation of the pituitary gland, limited blood supply (as experienced in a stroke ), trauma or abnormal
Hypopituitarism Professionals only. hypopituitarism,, Print this article, decrease chromophobeadenoma. In some cases hypopituitarism is inherited. When http://www.amershamhealth.com/medcyclopaedia/Volume III 1/HYPOPITUITARISM.asp
Extractions: *For Medical Professionals only, registration required Hypopituitarism, decrease or ablation of pituitary function from various causes, including surgery, infections, irradiation, postpartum necrosis and chromophobe adenoma. In some cases hypopituitarism is inherited. When the pituitary is affected during the time of skeletal growth, abnormalities of bone development occur. Delay in the appearance and growth of ossification centres as well as in their fusion and disappearance is characteristic. The growth plate remains open and its metaphyseal side is "closed off" as bone abuts on the cartilaginous tissue. Immature body proportions and facial features, abnormal distribution of fat, and delay in eruption of secondary teeth are among the features of hypopituitarism.
Hypopituitarism hypopituitarism,, Print this article, Unlike adults hypopituitarism secondaryto pituitary microadenoma or macroadenoma is rare in childhood. http://www.amershamhealth.com/medcyclopaedia/Volume VII/HYPOPITUITARISM.asp
Extractions: *For Medical Professionals only, registration required Hypopituitarism, decreased or absent function of the pituitary gland. In children hypopituitarism may be caused by the presence of tumours, such as craniopharyngioma , optic chiasm or hypothalamic glioma, or germinoma. Unlike adults hypopituitarism secondary to pituitary microadenoma or macroadenoma is rare in childhood. Hypopituitarism may also be seen after surgery particularly for lesions in the suprasellar cistern. Congenital abnormalities, such as pituitary hypoplasia or aplasia may also occur. Pituitary aplasia is usually fatal at birth. Hypoplasia results in varying degrees of hypopituitarism including adenohypophyseal and neurohypophyseal deficiencies. Many of these patients are found to have a small pituitary gland and fossa and the posterior pituitary may be in an ectopic position, usually in the region of the pituitary infundibulum or hypothalamus. These anomalies may only be detected by high resolution coronal and sagittal MR imaging of the pituitary region. An ectopic pituitary is seen as a bright spot in the region of the tuber cinereum on sagittal T1-weighted sequences with concomitant absence of the normal posterior pituitary bright spot in the pituitary fossa. The pituitary fossa may be small and appear empty, an 'empty sella'. The condition may be associated with
