Product Description
Dengue fever, and its more recent severe form known as dengue hemorrhagic fever, is the most important arthropod-transmitted viral disease of humans in the world today. Each year 50-100 million cases of dengue fever and several hundred thousand cases of dengue hemorrhagic fever occur. The dengue pandemic has intensified in the past 20 years, with expanding geographical distribution of both the mosquito vector and the viruses, and increased epidemic activity. Today, dengue is a global disease of the tropics, and is one of the most important emerging tropical diseases, with over half of the world population at risk. Research on dengue viruses and the diseases they cause has expanded greatly in the last two decades. However until now there has been no comprehensive volume to summarize and synthesize such information. This book fills this gap. It covers all relevant topics including history, epidemiology, virus-vector relationships, transmission, clinical aspects and treatment, the viruses and immune responses, as well as prevention and control. Written by international authorities from the Americas, Asia, Europe and Australia, the book represents an essential resource for research students and scientists, public health officials and physicians concerned with tropical medicine, virology, medical entomology and public health. ... Read more

Product Description
This unique volume presents an up-to-date review of one of the world smajor health problems -- diseases caused by the four dengue viruses. Itbegins with an insightful story of the origin of dengue disease outbreaks,including the emergence of severe and fatal dengue hemorrhagic fever. Thenature, structure and biology of the four dengue viruses are described, and amajor portion of the book is focused on the epidemiology of dengue as amosquito-borne disease. This is complemented by critiques of existing mosquitocontrol programs by three groups of outstanding authorities. The strongestelement of the volume is its comprehensive description of the currentunderstanding of dengue disease pathogenesis, followed by an analysis of thepros and cons of five of the most controversial areas in the field: the WHODEF case definition, secondary dengue infections, virulent viruses, the roleof abnormal T cells and autoimmunity.

Contents: Dengue: Overview and History (S B Halstead); The Infectious Agent (DW C Beasley & A D T Barrett); Epidemiology (S B Halstead); Resistance toInfection (D W Vaughn et al.); Clinical Features of Dengue (J Farrar);Management of Dengue (B Wills); Pathogenesis: Risk Factors Prior to Infection(S B Halstead); Elimination of Infection (A L Rothman & F A Ennis);Pathophysiology (S B Halstead); Diagnosis of Dengue Virus Infections (T P Endyet al.); The Control of Dengue Vectors (N G Gratz & S B Halstead); BiologicalControl of Dengue Vectors: Promises from the Past (B H Kay); Mosquito Control:Behavioral and Community Interventions (P Winch et al.); Controversies (JRigau-Perez et al.). ... Read more

Product Description
Dengue is an endemic viral disease affecting human population in tropical and subtropical regions around the world, predominantly in urban and semi-urban areas. Dengue fever (DF) and its more serious forms, the dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) are becoming important public health problems. The global prevalence of dengue has grown dramatically in recent decades. An estimated 2.5 billion people in more than 100 countries are at risk of acquiring dengue viral infection with more than 50 million new infections being projected annually, between 20,000 and 25,000 deaths, mainly in children. This book aims to review the possible molecular mechanisms that attribute to the variation of Dengue virus (DENV) disease. Additionally, a description of the animal models that have been developed to study DENV pathogenesis and to test potential vaccines and therapeutics are reviewed. This book also reviews the current understanding of DENV pathogenesis and the challenges confronting vaccine and therapeutic developers.Other chapters in this book examine the responses of target cells, including dendritic cells in people infected with DENV, recent developments in the molecular diagnosis for dengue virus, the mathematical models on dengue transmission and control, and a discussion of the ways in which to prevent and control dengue outbreaks. ... Read more

Product Description
This scarce antiquarian book is a selection from Kessinger Publishing's Legacy Reprint Series. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment to protecting, preserving, and promoting the world's literature. Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone! ... Read more

Product Description
Contributed articles. ... Read more

Product Description
Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are four serotypes of dengue virus, of which DENV-2 has been the most prevalent in many recent epidemics. Following primary infection, lifelong immunity develops, preventing repeated assault by the same serotype. However, the non-neutralizing antibodies from a previous infection or maternally acquired antibodies are thought to form complexes with a different serotype during a subsequent infection and cause dengue haemorrhagic fever/dengue shock syndrome, which can be fatal. There is no treatment or vaccine available today that can combat this emerging and uncontrolled disease.

This book features contributions from the world’s leading researchers working on dengue and related flaviviruses who examine the current state of the art in the molecular biology of the dengue virus. Particular emphasis is placed on the structure and function of the virus and the targeting of virus proteins by potential antiviral agents. The pathogenesis of dengue and dengue haemorrhagic fever are discussed in detail, especially the target cells and the specific receptors on these cells, thereby developing a clear overview of host and viral factors that contribute to dengue haemorrhagic fever. Finally, the book reviews the therapeutic options, paying particular attention to ways in which vector, host and environment can play a critical role in the spread of this disease.

With dengue fever and other emerging viral diseases becoming increasingly prevalent around the world, this book provides valuable insight into the virus that causes this disease and potential ways to manage it. It is essential reading for all those working in tropical diseases, public health and virology.

Praise from the reviews:

"The book provides an excellent summary of dengue/flavivirus research and is important for individuals and institutions interested in emerging infectious diseases." MICROBIOLOGY TODAY ... Read more

Product Description
This book has been created for patients who have decided to make education and research an integral part of the treatment process. Although it also gives information useful to doctors, caregivers and other health professionals, it tells patients where and how to look for information covering virtually all topics related to dengue (also Break bone fever; Breakbone fever; Dandy Fever; Dengue Hemorrhagic Fever; Dengue Shock Syndrome; Dengue-like disease), from the essentials to the most advanced areas of research. The title of this book includes the word official. This reflects the fact that the sourcebook draws from public, academic, government, and peer-reviewed research. Selected readings from various agencies are reproduced to give you some of the latest official information available to date on dengue. Given patients' increasing sophistication in using the Internet, abundant references to reliable Internet-based resources are provided throughout this sourcebook. Where possible, guidance is provided on how to obtain free-of-charge, primary research results as well as more detailed information via the Internet. E-book and electronic versions of this sourcebook are fully interactive with each of the Internet sites mentioned (clicking on a hyperlink automatically opens your browser to the site indicated). Hard-copy users of this sourcebook can type cited Web addresses directly into their browsers to obtain access to the corresponding sites. In addition to extensive references accessible via the Internet, chapters include glossaries of technical or uncommon terms. ... Read more

Product Description
This is an EXACT reproduction of a book published before 1923. This IS NOT an OCR'd book with strange characters, introduced typographical errors, and jumbled words.This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ... Read more

Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

Product Description
Originally published in 1898. This volume from the Cornell University Library's print collections was scanned on an APT BookScan and converted to JPG 2000 format by Kirtas Technologies.All titles scanned cover to cover and pages may include marks, notations and other marginalia present in the original volume. ... Read more

Product Description
This digital document is a journal article from Bioresource Technology, published by Elsevier in 2007. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
Investigations were made to test the larval toxicity and smoke repellent potential of Albizzia amara and Ocimum basilicum at different concentration (2%, 4%, 6%, 8% and 10%) against the different instar (I, II, III and IV) larvae and pupae of Aedes aegypti. The LC"5"0 values of A. amara and O. basilicum for I instar larvae was 5.412 and 3.734, II instar 6.480 and 4.154, III instar 7.106 and 4.664, IV instar 7.515 and 5.124, respectively. The LC"5"0 and LC"9"0 values of pupae were 6.792%, 5.449% and 16.925%, 15.474%. The smoke toxicity of A. amara was more effective against A. aegypti than the O. basilicum. ... Read more

Product Description

Scientific research on dengue has a long and rich history. The literature has been touched by famous names in medicine- Benjamin Rush, Walter Reed, and Albert Sabin, to name a very few- and has been fertile ground for medical historians . The advances made in those early investigations are all the more remarkable for the limited tools available at the time. The demonstration of a viral etiology for dengue fever, the recognition of mosquitoes as the vector for transmission to humans, and the existence of multiple viral variants (serotypes) with only partial cross-protection were all accomplished prior to the ability to culture and characterize the etiologic agent. Research on dengue in this period was typically driven by circumstances. Epidemics of dengue created public health crises, although these were relatively short-lived in any one location, as the population of susceptible individuals quickly shrank. Military considerations became as a major driving force for research. With the introduction of large numbers of non-immune individuals into endemic areas, dengue could cripple military readiness, taking more soldiers out of action than hostile fire. Dengue and dengue hemorrhagic fever, which assumed pandemic proportions during the latter half of the last century, have shown no indication of slowing their growth during this first decade of the twenty-first century. Challenges remain in understanding the basic mechanisms of viral replication and disease pathogenesis, in clinical management of patients, and in control of dengue viral transmission. Nevertheless, new tools and insights have led to major recent scientific advances. As the first candidate vaccines enter large-scale efficacy trials, there is reason to hope that we may soon "turn the corner" on this disease.

Product Description
This new edition has been produced to make widely available to health practitioners, laboratory personnel, those involved in vector control and other public health officials, a concise source of information of worldwide relevance on dengue. The guidelines provide updated practical information on the clinical management and delivery of clinical services; vector management and delivery of vector control services; laboratory diagnosis and diagnostic tests; and surveillance, emergency preparedness and response. Looking ahead, some indications of new and promising avenues of research are also described. Additional and more detailed specific guidance on the various specialist areas related to dengue are available from other sources in WHO and elsewhere, some of which are cited in the references.

This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity, since many aspects of the prevention and control of dengue are currently being investigated in a variety of studies. The guidelines contain the most up-to-date information at the time of writing. However, the results of studies are being published regularly and should be taken into account. To address this challenge, the guide is also available on the Internet and will be updated regularly by WHO.



... Read more