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Kings' College, London, UK. Laboratory manual providing methods for detection, isolation, identification, and characterization of mycoplasmas, with an emphasis on those of medical and veterinary significance. ... Read more

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A text intended for researchers and students in cell biology, genetics and molecular biology, developmental biology, biochemistry and biophysics. The complex problem of the relationship between nuclear structure and function demands a multidisciplinary, multifaceted approach. This laboratory guide is designed for researchers, from graduate students to professors, who need detailed protocols and general discussions on a broad range of techniques. The volume presents a selection of different methodological approaches for the analysis of nuclear structure and function - from cytological to molecular to genetic. These include visualization of nucleic acid sequences using hybridization probes, visualization of proteins using immunological probes, isolation of chromatin fractions, mapping "in vitro" protein-DNA interactions, reconstitution of functional templates and nuclear substructures, and genetic approaches to identifying and characterizing chromosomal components. ... Read more

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This up-to-date, authoritative laboratory manual can be used with the new edition of Biology, by Peter H. Raven and George B. Johnson, or with any general biology text. ... Read more

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International biobank collaborations allow for studies with large number of subjects where generalizability of findings across populations can be investigated, which means establishing quality criteria concerning the nature of the sample, conditions of sample storage, and the adequacy of available information is of vital importance. Methods in Biobanking brings together contributions from experts in the field in order to aid in the establishment of this much needed consistency. The volume discusses how to use existing collections of biological material to answer significant questions concerning the cause of disease without violating the personal integrity of participating sample donors, the ethical issues surrounding biobanks, guidelines for the use of coding systems and the use of biocomputing and registry linkages in research projects, as well as many other key subjects. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results.Authoritative and cutting-edge, Methods in Biobanking seeks to provide scientists with the tools necessary to take advantage of the tremendous current resources of the world’s biobanks and strengthen those resources for the future. ... Read more

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In recent years there has been a clear rise in scientific collaboration, as well as in studies on the subject. While most scholars examine disciplines traditionally known to be collaborative, such as physics and space research, this book focuses on biology. It investigates the growing collaboration in the life sciences, or the emergence of what is called 'big biology'. While the Human Genome Project is often presented as the first large-scale research project in biology, cooperation in the life sciences has a longer history. A comparison between centralised 'big physics' and 'big biology' reveals how the latter has a networked structure, which evolved in interaction with the integration of information and communication technologies. By concentrating on the construction of these networks, three contemporary large-scale research collaborations are analysed: the Census of Marine Life that aims to make an inventory of life in the oceans, the Silicon Cell initiative that wants to design a replica of a cell in a computer, and the VIRGO consortium, which investigates host-virus interaction to develop a new therapy against influenza. This book demonstrates how the process of making science bigger, or the 'supersizing of science', transforms the ways in which science is organised while it also changes the work of scientists involved. As such, this has both scholarly and professional implications for the next generation of scientists. ... Read more

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Nottingham University, U.K.Reviews and discussions of the most current sequence analysis software packages for both desktop and mainframe machines. Chapters are arranged by function. For researchers. 15 contributors, 8 U.S. DNLM: Sequence analysis--methods. ... Read more

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The papers assembled in this volume bring the reader to the forefront of research on the third component of complement, one of the most versatile and multifunctional molecules known to date. Unlike publications on individual characteristics, this vollume brings together all the structural and functional aspects of C3 and the C3-binding proteins, the latter including serum proteins, cell surface receptors and proteins of foreign origin. A wealth of information on the various aspects of the genetics, chemistry, biology and pathophysiology of C3 and of the 20 different proteins described to date to react with C3 is presented in numerous concise and comprehensive reviews. ... Read more

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This special issue of the Advances in Experimental Medicine and Biology presents much of the research described at the recent 2nd International Tissue Engineering Conference held in Crete in May 2005. The conference brought together over 150 researchers from around the world to examine the emerging and most advanced aspects of their particular field. The chapters reflect a diverse group of authors, including both clinicians and academicians.

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The papers presented in this volume are from a conference which was founded as a forum for scientific exchange among physicians, engineers, computer scientists and physiologists working in the application of computer technology to problems in clinical and experimental cardiology. ... Read more

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The proliferation of extracellular matrix family members reflects the progress in cloning techniques in recent years. PCR, in particular, has made a tremendous difference. These technical advances are covered in this volume. ... Read more

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In Situ Hybridization: A Practical Approach is a comprehensive practical guide with step-by-step laboratory protocols for the preparation of cloned DNA, RNA, and oligonucleotide probes (with both radioactive and non-radioactive labels) and their hybridization to mRNA, viral DNA, and chromosomal DNA. Methods are provided for the analysis of cells, tissue sections, and whole embryos. In addition, techniques are presented for carrying out in situ hybridization in combination with the immunochemical detection of protein, and for using it at the electron microscopic level. This detailed work is essential for any researcher wishing to master the widespread applications of this important biotechnology. ... Read more

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Exellent and newest protocol
This book gives newest and exellent protocol. Contents are not so big but enough detail to follow experiments. ... Read more

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Tissue Engineering, Second Edition, provides a comprehensive volume that integrates a wide spectrum of methods required to implement current and future progress in tissue engineering. Leading experts in various disciplines provide examples of recent advances in tissue engineering-related methodologies. Authors present authoritative discussions on topics including in vitro expansion of tissue cells by conditional proliferation; stem cell engineering using transducible Cre recombinase; skeletal stem cells for tissue engineering; synthetic hydrogel matrices for guided bladder tissue regeneration; artificial skin; artificial pancreas; cardiomyocytes from human and mouse embryonic stem cells; and biological scaffolds for heart valve tissue engineering.

Tissue Engineering, Second Edition, supplies an understanding of diverse technologies and methods used to drive tissue engineering into a clinical reality. The knowledge contained in this volume represents the impressive progress made in the decade that tissue engineering has rapidly evolved.