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With detailed contributions from more than 40 leading authorities on the topic, this Third Edition comprehensively explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GvHD)-offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GvHD prevention and treatment. ... Read more

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This digital document is an article from Gale Encyclopedia of Medicine, 3rd ed., brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 837 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.The third edition of this authoritative, comprehensive, in-depth medical guide features information on medical topics in language accessible to adult laypersons. Disease/disorder articles typically cover definition; description; causes and symptoms; diagnosis; treatments; prevention; and more. Test/treatment articles typically cover definition; purposes; precautions; preparation; risks; normal and abnormal results; and much more. ... Read more

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The article is excerpted fromGale Encyclopedia of Cancer
The resource students and researchers will turn to for reliable, up-to-date and clearly written information, the Gale Encyclopedia of Cancer is a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures. The Encyclopediaincludes entries covering cancers, cancer drugs, treatments, sideeffects and diagnostic procedures. Entries typically include thefollowing elements:

• Causes and Symptoms
• Definition
• Description
• Diagnosis
• Prevention
• Resources
• Risks
• Special Concerns
• And more

An appendix provides complete contact information for cancercenters, national support groups, government agencies and researchgroups. Features include anatomical illustrations of the major bodysystems, a subject index and approximately 200 photographs and drawings. ... Read more

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This digital document is an article from Skin & Allergy News, published by International Medical News Group on July 1, 2003. The length of the article is 732 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Immunosuppressive Tx may get boost from adjunctive use of ECP. (Promising for Graft-vs.-Host Disease).(extracorporeal photophoresis )
Author: Mitchel L. Zoler
Publication: Skin & Allergy News (Magazine/Journal)
Date: July 1, 2003
Publisher: International Medical News Group
Volume: 34Issue: 7Page: 24(1)

Distributed by Thomson Gale ... Read more

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The article is excerpted fromGale Encyclopedia of Medicine.

Consultthe second edition of this authoritative, comprehensive, in-depthmedical guide for information on more than 1,700 medical topics inlanguage accessible to adult laypersons. Presented in a singlealphabetical sequence, articles range in length from one or twoparagraphs for minor topics, to several pages or more for major topics.Disease/disorder articles typically cover definition; description;causes and symptoms; diagnosis; treatments; prevention; and more.Test/treatment articles typically cover definition; purposes;precautions; preparation; risks; normal and abnormal results; and muchmore. This second edition includes more than 200 new entries, 300updated entries, approximately 650 color images and illustrations, anda comprehensive subject index. New features include biographical andhistorical sidebars throughout the text.

Disease/disorder articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the disorder
• Descriptions -- overview of the disorder; who gets it and why
• Causes & symptoms -- process, substance or organism thatproduces the condition; any risk factors that increase susceptibilityto the condition; signs and symptoms of the disease
• Diagnosis -- overview of procedures and tests used todiagnose the condition; how the test is done; who should be tested andwhen; time required; cost; whether it's typically covered by insurance
• Treatments -- overview of conventional methods of care ormanagement of the condition, such as drugs, surgeries, physicaltherapy, etc.
• Alternative treatments -- overview of alternative/complementary therapies that may be used to treat the condition
• Prognosis -- probable outcome of the disease
• Preventions -- what actions can be taken to prevent the condition from occurring

Test/treatment articles contain some or all of the following sections:

• Definitions -- brief dictionary-style definition of the test/treatment
• Purposes -- why and when this test/treatment is prescribed
• Precautions -- when this test/treatment should not be prescribed
• Descriptions -- overview of the test/treatment including cost,length of time required, procedures followed, whether typically coveredby insurance
• Preparation -- pre-test treatment procedures, if any
• Aftercare -- post-test treatment procedures, if any
• Risks -- any complications/side effects commonly associated with the test/treatment
• Normal results -- for tests, describes the normal values; for treatments, describes the anticipated outcomes
• Abnormal results -- defines abnormal test values

Published/Released: December 2001

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Students, researchers, and patients can find reliable, up-to-date and clearly written information in “The Gale Encyclopedia of Cancer,” a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures.

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Chronic graft versus host disease (GVHD) is the most common complication of allogenic bone marrow transplantation. Because of the protracted clinical course of chronic GVHD, transplant centers and hematology/oncology offices are inadequately equipped to manage these immuno-incompetent patients with a multi-system disorder. Practitioners need to be able to recognize and effectively manage chronic GVHD as a late effect of more than half of allogenic transplantations. The text is oriented for the clinician, with chapters covering staging, organ site and system-specific manifestations, treatment options, and supportive care. Drs. Georgia B. Vogelsang and Steven Z. Pavletic have been pioneers in the recognition of the multi-organ complexity of this disease and have gathered the input of a variety of subspecialist physicians for this book. This book fills the gap in practical literature on chronic GVHD, providing a comprehensive, up-to-date, and clinically relevant resource for anyone who deals with cancer patients post-transplant. ... Read more

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This book provides a historical perspective of graft-vs-host disease as well as the discussion of the mechanisms involved in graft-vs-host disease. Understanding the mechanisms of graft-vs-host disease will allow for the development of better preventative and therapeutic measures. This field continues to be an area of active research as we understand better and better how T-cells become activated and the important factors associated with activated T-cells such as specific cytokines released or specific cytokines which may effect T-cell functions. These particular aspects are covered in this book as well as a discussion on the potential therapies and prophylactic regimens associated with graft-vs-host disease. ... Read more

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Practical Hematopoietic Stem Cell Transplantation is the only comprehensive yet practical guide to the total care of the transplant patient. It provides a ready source of reference to help health care professionals involved in the management of patients requiring bone marrow and stem cell transplantations – covering many of the infections and complications that may arise.

An essential, practical manual for all those working in the field of bone marrow and stem cell transplantation

• A balanced practical text aimed at the whole multi-disciplinary team
  
• Easy to use - practically organized - covering all aspects of pre and post transplant care – including social and psychological aspects
  
• Experienced and well respected editorial team

Whether you are an established specialist in hematology/oncology, nursing specialist, trainee, or any other member of the hematopoietic stem cell transplant team, this book will answer all your questions about the medical, social and psychological pre and post transplant, patient care. ... Read more

Customer Reviews (1)

Adequate intro for us non-specialists
As an ID doc who seems BMT, I was looking for a "BMT for Dummies" book to make sure my fundamentals were sound, and to have as a resource for the ID fellows.This fit the bill reasonably well, with definitions for a lot of basic concepts and procedures.It gives the basics of most aspects, from indications, the mechanics of matching and transplanting, complications, and infections.
I've given several chapters to the fellows, who liked them and felt that it filled in important gaps in basic knowledge.I haven't gotten feedback whether the onc fellows like it.
This small book does not pretend to have the true depth needed for a real practicioner.
The target audiences I picture might be the following:
- Consultants who need to understand the process better
- Heme/onc fellows beginning their rotations
- Nurses, NPs, PAs who are just beginning to work with HSCT patients and need a place to start.
The 4/5 rating comes from a general sense of adequacy, but I can't find many specific complaints.It needs updating in cord blood transplants.The ID chapters seem a bit short, but I'm biased.
I felt this was a good supplement to Dowden et al. "Transplant Infections" to round out the BMT ID experience.
... Read more

Product Description
Subject of the book is the detailed description of the clinical and diagnostic pathology of one of the strangest diseases of man, the so-called Graft-versus-Host-Disease (GvHD). This disease is caused by the reaction of certain donor cells (T-lymphocytes) with tissue of the recipient, i.e. after allogeneic bone marrow transplantation, a life-saving measure in patients with leukemia, aplastic anemia etc. In this context a GvHD may develop with severe disease symptoms in skin, gastrointestinal tract, liver, and other organs. If the complication is recognized in time an effective treatment of the potentially lethal GvHD is possible.However, this requires a rapid and reliable recognition of GvHD lesions. The book is based on the histopathological study of more than 1000 biopsies and 50 autopsies performed by the author as the reference pathologist of the center for bone marrow transplantation of the University of Ulm. ... Read more

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This digital document is an article from American Journal of Immunology, published by Science Publications on January 1, 2009. The length of the article is 4955 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.

From the author: Key words: Absolute lymphocyte count; autologous graft versus tumor effect; autologous hematopoietic stem cell transplantation; survival; malignancies

Citation Details
Title: Clinical evidence of autologous graft versus tumor effect.(Report)
Author: Luis F. Porrata
Publication: American Journal of Immunology (Magazine/Journal)
Date: January 1, 2009
Publisher: Science Publications
Volume: 5Issue: 1Page: 1(7)

Article Type: Report

Distributed by Gale, a part of Cengage Learning ... Read more

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This digital document is an article from Dermatology Nursing, published by Thomson Gale on February 1, 2007. The length of the article is 1360 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

From the author: Dermatology Nursing Essentials: A Core Curriculum (2nd edition) was written to provde the reader with core knowledge about the specialty of dermatology nursing. Key points from the text are highlighted to test and review your dermatology nursing knowledge. These quick hits of information are no substitute for the indepth analysis provided in the Core Curriculum, but are designed to whet your appetite for the comprehensive content that the Core delivers. References for the information presented here can be found in the Core Curriculum. To order your personal copy of the Core, visit DNA's Web site at www.dnanurse.org or call (800) 454-4DNA.

Citation Details
Title: Cutaneous manifestations of systemic disease: sarcoidosis, GVHD, behcet's disease, and pyoderma gangrenosum.(Dermatology Nursing Essentials: Core Knowledge)(Author abstract)
Author: Sue Ann McCann
Publication: Dermatology Nursing (Magazine/Journal)
Date: February 1, 2007
Publisher: Thomson Gale
Volume: 19Issue: 1Page: 75(3)

Article Type: Author abstract

Distributed by Thomson Gale ... Read more

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Students, researchers, and patients can find reliable, up-to-date and clearly written information in “The Gale Encyclopedia of Cancer,” a comprehensive survey of 120 cancers, cancer drugs, traditional and alternative treatments and diagnostic procedures.