Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

Customer Reviews (1)

Helping consumers chart the past, present and future prognosis of treatments themselves
The third updated edition of the consumer health reference SEXUALLY TRANSMITTED DISEASES SOURCEBOOK updates all details about STDs in the general population as well as in specific groups, surveying all kinds of infections, strategies for prevention, and the latest advancements in treatment. The latter includes current research initiatives as well, helping consumers chart the past, present and future prognosis of treatments themselves.

Diane C. Donovan
California Bookwatch
... Read more

Product Description
Frontiers in Viral Hepatitis provides a compilation of the research from over 40 key opinion leaders in the field of Hepatitis.The book focuses on the latest advances in the search for new, more effective therapeutic options and related topics in viral hepatitis.These include regulatory issues, epidemiology, and emerging viruses; immunology and vaccines; viral hepatitis B and C infections in children; genetics pathology and viral diagnosis; cell systems and animal models; novel therapeutics for hepatitis B and C; resistance and therapeutic strategies in humans; and prevention and treatment options for hepatocellular carcinoma.

The breadth of information published in this volume provides insight into current prevention and treatment options.Recent advances in our understanding of the molecular biology, immunology and pathogenesis of hepatitis viruses have accelerated at a remarkable rate, offering a more comprehensive perspective on hepatitis. ... Read more

Product Description
Chronic hepatitis has been in the focus of intense scientificresearch for decades. Recently, considerable progress and exciting newinsights into pathogenesis and resulting therapeutic strategies havebeen made. Replication of hepatitis B and C viruses and details oflife cycle in the host have been well characterised. Immunology ingeneral and immunopathology of the liver in viral and autoimmunehepatitis have shown more specific mechanisms of host defence and newmodels of autoimmune aggression have been developed. The role ofapoptosis in liver damage is now well appreciated and has beenanalyzed precisely. Essential steps of fibrogenesis as a consequenceof chronic liver damage are better understood by now and newstrategies for its prevention have evolved. Chronic hepatitis is theleading cause of liver cell carcinoma, the molecular basis of whichhas been more clearly elucidated. This increasing knowledge willprovide a sound basis for more effective therapy in chronic hepatitisand its life-threatening consequences.This book, the proceedings of the Falk Workshop on Chronic Hepatitis,held in Cologne, Germany, on January 27-28, 2000, brings togetherexperts from different fields of research such as virology,immunology, pathology, cell and molecular biology, as well as clinicalmedicine, and disusses in depth the novel findings in basic andclinical research. ... Read more

Product Description
This text documents the explosion of research efforts surrounding this human pathogen. It offers a full account of the hepatitis delta virus, from its natural history and diagnosis to its prevention and treatment. Using modern molecular techniques, the book examines the ability of HDV to variate at the genetic level, and presents initial studies of the therapeutic control of HDV and its role as a complication in liver transplantation programmes. It also examines current vaccination programmes for hepatitis B and their potential applications for the control of HDV. ... Read more

Product Description
Hepatitis C is recognized as one of the most important new diseases afflicting man.The discovery, diagnosis and initial treatments of hepatitis C virus (HCV) infection are all perfect examples of the increasing impact molecular biology is currently having on disease management throughout the globe. Both the intensity and breadth of HCV research are growing at a remarkable pace and exciting new discoveries are becoming almost commonplace.

This book reviews the current state of progress in HCV molecular biology and discusses the questions that are currently facing molecular investigators. Thechapters provide in-depth reviews of the most critical areas of HCV molecular research today. Topics covered include: the HCV genome and life cycle, the HCV core protein, glycoproteins, protease and serine protease, helicase, regulator proteins, replicon systems, regulation of host defense and adaptive immunity,vaccine design, and cell culture systems. ... Read more

Customer Reviews (1)

A superb volume by internationally renowned authors discussing the most recent aspects of HCV
This book presents an excellent comprehensive review of historical and current research on hepatitis C viruses. The book is expensive, but of outstanding value. Each chapter is well written by an acknowledged expert in the field and authoritative, providing valuable references to a large body of work. I am pleased to recommend this book to anyone working in viral pathogenesis, viral genomics and antiviral research, as well as infectious disease physicians and educators in virology.
... Read more

Product Description
In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading."Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so. ... Read more

Product Description
This econometric study covers the latent demand outlook for hepatitis c virus (HCV) therapeutics across the regions of Greater China, including provinces, autonomous regions (Guangxi, Nei Mongol, Ningxia, Xinjiang, Xizang - Tibet), municipalities (Beijing, Chongqing, Shanghai, and Tianjin), special administrative regions (Hong Kong and Macau), and Taiwan (all hereafter referred to as "regions"). Latent demand (in millions of U.S. dollars), or potential industry earnings (P.I.E.) estimates are given across some 1,100 cities in Greater China. For each major city in question, the percent share the city is of the region and of Greater China is reported. Each major city is defined as an area of "economic population", as opposed to the demographic population within a legal geographic boundary. For many cities, the economic population is much larger that the population within the city limits; this is especially true for the cities of the Western regions. For the coastal regions, cities which are close to other major cities or which represent, by themselves, a high percent of the regional population, actual city-level population is closer to the economic population (e.g. in Beijing). Based on this "economic" definition of population, comparative benchmarks allow the reader to quickly gauge a city's marketing and distribution value vis-a-vis others. This report does not discuss the specific players in the market serving the latent demand, nor specific details at the product level. The study also does not consider short-term cyclicalities that might affect realized sales. The study, therefore, is strategic in nature, taking an aggregate and long-run view, irrespective of the players or products involved.
... Read more

Product Description
Hepatitis B is a disease of the liver caused by the Hepatitis B virus (HBV), a member of the Hepadnavirus family and one of several unrelated viral species which cause viral hepatitis. It was originally known as "serum hepatitis" and has caused current epidemics in parts of Asia and Africa. Hepatitis B is recognised as endemic in China and various other parts of Asia. The proportion of the world's population currently infected with the virus is 3 to 6%, but up to a third have been exposed. Symptoms of the acute illness caused by the virus include liver inflammation, vomiting, jaundice, and rarely, death. Chronic hepatitis B may cause liver cirrhosis which may then lead to liver cancer. ... Read more

Product Description
This second edition covers almost all aspects of HCV research, reflecting the wide range of knowledge gathered since the genome of HCV was identified. All chapters have been updated and new chapters focus on the molecular characterization of HCV, the immunopathogenesis of HCV infection and the liver histology of hepatitis C. ... Read more

Product Description

Acute and chronic hepatitis and hepatitis-related diseases such as liver failure, liver cirrhosis and hepatocellular carcinoma are among the most important causes for disabilities and death. Hepatocellular injury is due to a variety of agents including viruses, toxins, radiation, injury and drugs but also bacteria, parasites and autoimmune reactions.

This volume reviews today’s knowledge about hepatitis with emphasis on comparative aspects between hepatitis in humans and animals, but also between different etiological agents. This particular viewpoint makes the book relevant for scientists from both human and veterinary medicine, gastroenterologists, pathologists, virologists and students of human and veterinary medicine.

Customer Reviews (1)

A library reference covers all types of hepititis.
Sandra J. Judd edits the new first edition HEPATITIS SOURCEBOOK (0780807499), which offers basic consumer information on all the different types of hepatitis. Risk factors, prevention, transmission, and more offer tips for coping with chronic treatments and discussions of typical challenges. Both are packed with detail and information suitable for general-interest public library reference holdings. ... Read more

Product Description
Hepatitis B virus (HBV), discovered in 1966, infects more than 350 million people in the world. The infection of HBV is a leading cause of chronic carriage of the virus and progressive liver diseases, such as hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). HBV consists of a circular, partially double-stranded DNA molecule of 3.2 kb in length, which contains four overlapping reading frames that code for surface proteins (HBsAg), core proteins (HBcAg/HBeAg), the viral polymerase, and the transcriptional transactivator X protein. Chronic hepatitis appears to be due to a suboptimal cellular immune response that destroys some of the infected hepatocytes and does not purge the virus from the remaining infected hepatocytes, thereby permitting the persisting virus to trigger a chronic indolent necroinflammatory liver disease that sets the stage for development of HCC.However, the mechanisms responsible for malignant transformation in chronic HBV infection are not well defined, and both viral and host factors have been implicated in the process.All cases of HCC occur after many years of chronic hepatitis which could, theoretically, provide the mitogenic and mutagenic environment to precipitate random genetic and chromosomal damage, and lead to the development of HCC. Hepatitis B virus X protein (HBx), an important transforming inducer, plays a crucial role in HCC development. HBx has the capability to influence a variety of signal transduction pathways within the cells. Monitoring of the HBV genotypes and antibody to Hepatitis B x antigen (anti-HBx) are significant for predicting early diagnosis of liver cirrhosis and HCC. HBV and Hepatitis C virus or HIV coinfections can accelerate the course of chronic liver disease and facilitate progression to cirrhosis and HCC.As for therapy of liver diseases, five drugs are now FDA-approved for the treatment of HBV, including interferon (IFN), lamivudine, adefovir, entecavir, and peginterferon alfa-2a. Moreover, the prevention for HBV infection is very important. It is likely that the most important outcome of the research on HBV has been the invention, development, and application of the vaccine against HBV.However, at present most investigators focus on basic research rather than practical applications. The HBV research should be focused on animal models and clinical practice. The technology update in HBV research and the multisubject combination may be attached importance to next a few decades. Some molecular approaches, such as antisense, oligonucleotides, ribozymes, RNA interference targeting HBV mRNA, are available in antiviral therapies. ... Read more