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Targeted to patients, their families and allied health students, The “Gale Encyclopedia of Neurological Disorders” provides in-depth coverage of neurological diseases and disorders, including stroke, multiple sclerosis, Parkinson disease, Tourette Syndrome, Alzheimer's disease, cerebral palsy, vertigo, amnesia and epilepsy. Related topics include communication aids, electric personal assistive mobility devices, medications for treating neurological diseases and conditions, understanding the needs of Alzheimer patient caregivers and more. This two-volume set provides an alternative to resources that either fail to explore neurological disease in any depth and or do so at a level not appropriate for students and general readers.

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This digital document is an article from BIOTECH Patent News, published by Thomson Gale on September 1, 2005. The length of the article is 1171 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Sirna granted patent covering siRNAs targeting Huntington's Disease.
Publication: BIOTECH Patent News (Newsletter)
Date: September 1, 2005
Publisher: Thomson Gale
Volume: 19Issue: 9

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This digital document is an article from Transplant News, published by Transplant Communications, Inc. on January 16, 2001. The length of the article is 470 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Fetal nerve cells transplanted into brain of Huntington's disease patient appear to have survived.(Brief Article)
Publication: Transplant News (Newsletter)
Date: January 16, 2001
Publisher: Transplant Communications, Inc.
Volume: 11Issue: 1Page: NA

Article Type: Brief Article

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This is a Ph.D. dissertation. Huntington's Disease (HD) is a dominantly inherited late onset neurodegenerative disorder, initially affecting the basal ganglia and especially the head of the caudate nucleus.

Eventually, atrophy is more diffuse extending to the cerebral cortex and other brain nuclei. A triad of progressive motor, cognitive, and emotional symptoms characterizes adult onset HD.

Contents include: General Introduction and Aims of the Study, Cognitive Changes in Patients with HD and Asymptomatic Carriers of the HD Mutation, Recent Memory and Recognition Memory in Huntington's Disease, Habitual Learning ... Read more

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This digital document is an article from Family Practice News, published by International Medical News Group on May 15, 1999. The length of the article is 547 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Drug Combo Studied for Slowing Huntington's.
Author: Sherry Boschert
Publication: Family Practice News (Magazine/Journal)
Date: May 15, 1999
Publisher: International Medical News Group
Volume: 29Issue: 10Page: 57

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This digital document is an article from Science and Its Times, brought to you by Gale®, a part of Cengage Learning, a world leader in e-research and educational publishing for libraries, schools and businesses.The length of the article is 1465 words.The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase.You can view it with any web browser.The histories of science, technology, and mathematics merge with the study of humanities and social science in this interdisciplinary reference work. Essays on people, theories, discoveries, and concepts are combined with overviews, bibliographies of primary documents, and chronological elements to offer students a fascinating way to understand the impact of science on the course of human history and how science affects everyday life. Entries represent people and developments throughout the world, from about 2000 B.C. through the end of the twentieth century. ... Read more

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This digital document is an article from Family Practice News, published by Thomson Gale on May 15, 2006. The length of the article is 516 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Drug for Huntington's-related chorea deemed approvable.(News)
Author: Elizabeth Mechcatie
Publication: Family Practice News (Magazine/Journal)
Date: May 15, 2006
Publisher: Thomson Gale
Volume: 36Issue: 10Page: 8(1)

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This digital document is an article from Internal Medicine News, published by International Medical News Group on September 15, 2008. The length of the article is 358 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.

Citation Details
Title: Neuroleptic is first drug approved for relief of Huntington's chorea.(NEWS FROM THE FDA)
Author: Jeff Evans
Publication: Internal Medicine News (Magazine/Journal)
Date: September 15, 2008
Publisher: International Medical News Group
Volume: 41Issue: 18Page: 5(1)

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This digital document is an article from Science News, published by Science Service, Inc. on July 4, 2009. The length of the article is 497 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available immediately after purchase. You can view it with any web browser.

Citation Details
Title: Lab tests find Huntington's protein may have crony in killing brain cells: results could explain why only some neurons are vulnerable.(Genes & Cells)
Author: Tina Hesman Saey
Publication: Science News (Magazine/Journal)
Date: July 4, 2009
Publisher: Science Service, Inc.
Volume: 176Issue: 1Page: 10(1)

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This study focuses on the issues faced by spousal carers of Huntington's Disease (HD) sufferers, and explores the carer role in HD and defines the resources that are used by (or would be useful to) carers. The study uses unstructured, qualitative interviews of carers caring for their spouses in their own home. Topics explored during the interviews included: carers? perspective on their care-giving role and how that role had changed their lives, carers? motivations for caring and their doubts and problems, carers? plans for caring for future generations of HD relatives and facilitating factors and barriers to providing effective care.Spousal carers provide a very valuable, cost-effective service that mainly draws upon their own resources. ... Read more

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A common feature of numerous neurodegenerative disorders such as Parkinson's and Huntington's disease is the abnormal accumulation of aggregated proteins in distinct regions of the brain. Here, the author demonstrates that (-)- Epigallocatechin gallate (EGCG), a catechin present in green tea, is a potent inhibitor of this pathological process. EGCG prevents the aggregation of two different proteins by stabilizing an oligomeric conformation, leading aggregation-prone proteins on an alternative folding pathway in the misfolding cascade. This effect could be mediated by direct interaction between EGCG and proteins in an unfolded, open" conformation. EGCG also reduces the toxicity caused by misfolded proteins in cell culture model systems suggesting that the oligomeric protein species formed in the presence of the compound are not toxic to living cells. EGCG might therefore represent a chemical chaperone that can modulate misfolding and toxicity of proteins associated with neurodegenerative diseases and could provide the basis for the development of a novel pharmacotherapy for these fatal disorders." ... Read more

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Portraits of Huntington's is a joyful collection of profiles, essays, and quotes for and about those with Huntington's Disease. Portraits of Huntington'sfeatures award winning artist Ruth Hargrave's incredible portraits of eight individuals or family groups who are all in some way touched by this genetic disease.

Joy is a choice. Happiness is based on a set of circumstances, and Portraits of Huntington's asks us to choose joy. As with Faces of Huntington's,in each chapter is thematic, Knowledge, Laughter, Patience, Compassion, Faith, Love, Hope, and Joy.

Whether you are a person with Huntington's Disease, a caregiver, someone at-risk, a family member, a professional, or someone who simply cares, we all need joy in our lives. Somehow, despite the horror of Huntington's Disease, remarkable heroes are choosing joy every day. I hope their inspiring lives, coupled with my stories and Ruth's portraits, will encourage you to choose joy. ... Read more

Customer Reviews (4)

What a wonderful book
I know Huntington's is a devastating disease that destroys the person suffering with it and also complete families. But I also know so many people who have come through the experience as better people and that's what this book is about. We are all terminal from the moment we are born yet the author has done a magnificant job of helping the reader understand that joy is a choice.

This book is the perfect companion to Faces of Huntington's since that book features such hard stories about suicide, abuse, family dynamics from hell, and so much more. This book looks at another side of Huntington's. Both books are filled with heros. I love the author's writing style and I was sad when it was over. I know I'll read this book over many times in my life.

Compassionate, insightful resource
Carmen Leal has done what few could accomplish.She combines humor, compassion, and love with an insider's view of lives affected by Huntington's Disease.This is the place to go (along with her other book, "Faces of Huntington's") for factual, helpful information in an easy-to-read story format on the devastating genetic illness, Huntington's Disease.
Carmen is an inspiration!She offers light in a dim world, hope where there is despair, and love where none can be returned in kind.
"Portraits of Huntington's" and "Faces of Huntington's" are must-reads for anyone facing the challenges of life with this disease.
...

great book
Carmen has touched my heart with her stories of hope in a hopeless situation. She has written straight from the heart an awesome book in a down-to-earth style that anyone would enjoy.

Portraits of Huntingotn's
What a joyful book! Living with Huntington's Disease is hard for everyone in the family. But there really are some times filled with love and happiness and joy. Carmen has done a wonderful job of pulling together real life stories of people who choose joy through the lessons they have learned by being caregivers or having the disease or loving someone who does.

I especially liked the profiles of those selected accompanied by portraits drawn Ruth Hargrave. She is a wonderful artist and it was fun to put faces with the stories. I don't have Huntington's in my family, but a good friend does, and I read the book to be a support to that family. What I discovered from reading it is that, like Faces of Huntington's, this book is for everyone. Everyone needs to laugh, cry, be happy, think a lot, look at living heros, look at the good in others, and a lot more that Portraits of Huntington's helps you do.

This is a wonderful book and I am more enriched from having read it. ... Read more