1. Emphysema emphysema. March 19, 2003. of emphysema called alpha 1antitrypsin(AAT) deficiency-related emphysema. HOW DOES emphysema DEVELOP? http://www.lungusa.org/diseases/lungemphysem.html

Home Diseases A to Z Emphysema Search Site Local Search Enter Your ZIP Emphysema April 7, 2003 March 2002 How Serious Is Emphysema? Causes Of Emphysema How Does Emphysema Develop? Treatment For Emphysema ... Prevention of Emphysema WHAT IS EMPHYSEMA? Emphysema is a condition in which there is over-inflation of structures in the lungs known as alveoli or air sacs. This over-inflation results from a breakdown of the walls of the alveoli, which causes a decrease in respiratory function (the way the lungs work) and often, breathlessness. Early symptoms include shortness of breath and cough. Early symptoms of emphysema include shortness of breath and cough. Emphysema and chronic bronchitis together comprise chronic obstructive pulmonary disease (COPD). HOW SERIOUS IS EMPHYSEMA? Emphysema is a widespread disease of the lungs. Close to 2.8 million Americans have been diagnosed with emphysema. Emphysema ranks 15th among chronic conditions that contribute to activity limitations: almost 44 percent of individuals with emphysema report that their daily activities have been limited by the disease. Men tend to have higher rates of emphysema. In 1999, the emphysema prevalence rate was 53% higher in males compared to females.

2. EFFORTS-Main Website nonprofit organization, formed, funded and operated by patients with the disease,working to promote research for emphysema and related lung diseases. http://www.emphysema.net/bindex.html

Claycomo Plaza * 411 NE US HWY 69 * Claycomo, Mo. 64119 * FAX 816-413-0176 Emphysema (COPD) takes your breath away ABOUT EFFORTS LIVING WITH COPD ADVOCACY / AWARENESS Welcome About Us About EFFORTS The Origin of EFFORTS Our Official Position Our Official Goals ... World Members Contributions About Contributions EFFORTS List Join EFFORTS List List Conduct Guidelines How to send EMails How to manage Email ... View our Archives Other Member Lists Funday Caregivers Quitsters Walkers Complaints Complaint Department Search Search EFFORTS Website Everyday Support Living With COPD/Emphysema Exercise at Home - NIA Guide Coping Tips from Members Find a Pulmonary Rehab Facility ... Spiriva Users - First Member Survey 2002 Of Special Interest Lung Profiler © Treatment Decisions Oxygen Service- Member Surveys Spiriva Users - 2nd Member Survey 2003 ... Quitsters-Stop Smoking Group Miscellaneous Links Important Related Links Private Spiritual Assistance Background The Goose Story Talking Points Latest Statistics - NHLBI Latest Statistics - CDC Guides Newsmedia Samples Contacts Supplies Business Cards Brochures Pins Bumper/Window Stickers ... Videotapes (Rally) Current Projects Medicare Prescription Bills Eloquium Journalism Award Previous projects Efforts goes to Congress 3rd Annual D.C. Rally

3. Breathe Easy - Abnormal Lung Anatomy; Emphysema; What Happens With COPD. Guide offers illustrations of lungs with irritated bronchi due to emphysema. Download a video clip of the breathing process. http://www.lung.ca/copd/anatomy/emphysema.html

ABNORMAL LUNG ANATOMY What Happens With COPD Emphysema When you have emphysema, some of the air sacs deep in your lungs have been damaged. When the bronchi become irritated, the normal elasticity of the air sacs and the walls of the airways are destroyed. People with emphysema need to forcefully blow the air out in order to empty the lungs. Forcing the air out in this way puts pressure on the airways from the outside, compresses them and causes them to collapse. The walls of the tiny air sacs may even tear. Excessive coughing may cause the airways to collapse as well. MPG Clip (330K): A journey down the collapsing airway passages, and ending in the deteriorating alveoli. As the stretching and tearing of the walls of the air sacs continues, the lungs may become enlarged and less efficient at moving air into the lungs and contaminants out of the lungs. Because the walls of the air sacs are destroyed, there is less surface area available for gas exchange. Damage to the air sacs in the lungs not only results in difficulty breathing, but the heart also has to work harder to circulate blood through the lungs. All these changes make less oxygen available to the body. Emphysema is characterized by a large barrel-shaped chest, a poor air pumping system, and shortness of breath (SOB). In advanced stages, every breath is difficult. A cough may or may not be present with emphysema.

4. Emphysema emphysema is not curable, but it can be treated. Those who have it can behelped to live with it. Something can be done about emphysema today. http://www.lung.ca/diseases/emphysema.html

Emphysema is not curable, but it can be treated. Those who have it can be helped to live with it. It is a destructive disease for thousands of Canadians and their families. Over 1100 people die of it as a major cause each year. Something can be done about emphysema today. Who gets Emphysema? Persons with emphysema are, for the most part, males between 50 and 70 years old. Women get emphysema, too, but so far, not as often as men. However these statistics are changing as women are starting to smoke more, and at an earlier age. A very high percentage of the people who have emphysema smoke cigarettes and have been heavy smokers for many years. Frequently, they live in areas where air pollution is a constant problem. Some people are born with a lack of a substance called alpha-1 antitrypsin. This makes them more likely than others to get emphysema and at an earlier age. How it Attacks A person with emphysema doesn’t develop the disease suddenly. It comes on gradually. He or she has probably had several very bad colds each winter for the past few years, each accompanied by a heavy cough, and often with chronic bronchitis. The cough often persists between colds and becomes chronic. The thing that usually brings the patient to the doctor is that he or she has begun to feel short of breath on exertion in morning or evening or both. The patient may think he or she has asthma or heart disease.

5. Emphysema A description of emphysema, followed by links, clinical trials, associations and technical papers emphysema. emphysema is a chronic disease of the lungs which is characterized by parenchymal destruction distal to the http://emphysema.allbio.org/

Emphysema Emphysema is a chronic disease of the lungs which is characterized by parenchymal destruction distal to the terminal bronchioles. Smoking, air pollution, environmental or occupational hazards, and genetic factors may play a role in this disease. Symptoms of emphysema usually begin with breathing difficulty especially during exhalation, shortness of breath, an enlarged chest, and bluish skin color. Acne Allergy Antibiotics Antioxidants ... Wedding General Information - Overview Emphysema - from Temple University Hospital. Symptoms of Emphysema - by Creighton University School of Medicine. Emphysema - from American Lung Association. Surgery Helps Emphysema Patients Breathe Easier - from Saint Louis University. Emphysema - from Catholic Healthcare West. Emphysema - by Canadian Lung Association. Chronic Bronchitis and Emphysema - from St. Joseph's Healthcare, Hamilton. Emphysema - from the Hutchinson Family Encyclopedia. Emphysema, Congenital Lobar - from Northwestern Memorial Hospital. Emphysema - from University of Texas Medical Branch.

6. Alpha-1 Related Emphysema Information about A1AD related emphysema which is caused by an inherited lack of a protective protein Category Health Conditions and Diseases emphysema...... Alpha1 Related emphysema. March 19, 2003. WHAT IS ALPHA-1 RELATEDemphysema? Alpha-1 related emphysema or Alpha-1 deficiency, is http://www.lungusa.org/diseases/luna1ad.html

Home Diseases A to Z Article Search Site Local Search Enter Your ZIP Alpha-1 Related Emphysema April 7, 2003 March 2002 What is Alpha-1 Related Emphysema? How Is AAT Deficiency Inherited? Who Is Most At Risk? How Does Emphysema Develop? ... Additional Information WHAT IS ALPHA-1 RELATED EMPHYSEMA? Alpha-1 related emphysema or Alpha-1 deficiency, is caused by an inherited lack of a protective protein called alpha-1 antitrypsin (AAT). In normal and healthy individuals, AAT protects the lungs from a natural enzyme (called neutrophil elastase) that helps fight bacteria and clean up dead lung tissue. However, this enzyme can also eventually damage lung tissue if not neutralized by AAT. If allowed to progress, this form of emphysema becomes chronic and lung tissue continues to be destroyed; eventually it is fatal if the progress is not slowed down or halted. HOW IS AAT DEFICIENCY INHERITED? Every person inherits two AAT genes, one from each parent. A person has AAT Deficiency (Alpha-1) only if he or she inherits two abnormal genes. People who have only one abnormal gene and one normal AAT gene are "carriers.” Their AAT levels may be lower than normal, but not as low as the deficiency state, and their risk of significant health problems is much lower than those with the severe deficiency.

7. EFFORTS Signup Page Information about the organization which promotes research on emphysema. Also data and support for COPD.Category Health Conditions and Diseases......64119 * FAX 816413-0176 emphysema, A Chronic Obstructive Pulmonary Disease (COPD). Learnmore about emphysema (COPD) from folks who are living with it. http://www.emphysema.net/

Claycomo Plaza * 411 NE US HWY 69 * Claycomo, Mo. 64119 * FAX 816-413-0176 Emphysema, A Chronic Obstructive Pulmonary Disease (COPD) Emphysema (COPD) takes your breath away Learn more about Emphysema (COPD) from folks who are living with it If you are looking for more information or support about Emphysema or other Chronic Obstructive Pulmonary Disease (COPD), you have found the most energetic and comprehensive organization on the web. Be an informed patient. Learn that living with COPD, while a change in lifestyle, is not a death sentence. As well as providing a very vital support mailing list and educational resource for its members, we are also working to educate and inform patients and care providers as well as promote deeper research for more effective treatment and hopefully a cure for Emphysema and other Chronic Obstructive Pulmonary Disease. Be an activist in managing your own disease and join our EFFORTS to help promote vital medical research and education. If we don't do this, who will? EFFORTS is a 501(c)(3), non-profit organization that was formed, funded and is operated by patients with the disease. Membership is free. All contributions are tax-deductible.

8. NEF Home Frame Group promotes public awareness of this pulmonary disease and offers support to patients. Find treatment information and professional listings. 411 NE US HWY 69 * Claycomo, Mo. 64119 * FAX 816413-0176. emphysema, A Chronic Obstructive Pulmonary Disease (COPD) http://www.emphysemafoundation.org/

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9. Emphysema Wheelchairs EZ Chair A Wheelchair For Emphysema Patients emphysema affects over 1.6 million Americans, and ranks ninth among chronic conditions that contribute to inactivity (American Lung Association). Most people who have emphysema are older men, they outnumber women over 65%. http://www.ezchair.com/Emphysema.htm

Emphysema Emphysema affects over 1.6 million Americans, and ranks ninth among chronic conditions that contribute to inactivity (American Lung Association). Most people who have emphysema are older men, they outnumber women -over 65%. However when women have this condition they have a more severe case. Predictions are being made that women will have more of an increase in emphysema in the next 10 to 25 years. What is happening is that men are stopping smoking and women are just starting! Treatment and Care A doctor can diagnose emphysema based on your medical history, a physical exam, a chest X-ray, and a lung-function test (spirometry). By the time emphysema is detected, however, anywhere from 50-70 percent of your lung tissue may already be destroyed. At that point, your doctor may recommend the following: A program to help you stop smoking Avoidance of secondhand smoke Avoidance of dust, fumes, pollutants, and other irritating inhalants Physical therapy to help loosen mucus in your lungs (if chronic bronchitis accompanies the emphysema) Daily exercise A diet that includes adequate amounts of all essential nutrients Prescription medication which may include a bronchodilator, steroids, and antibiotics

10. NEF Home Frame Information about the organization that is dedicated to improving the quality of life for people with Category Health Conditions and Diseases emphysema...... http://emphysemafoundation.org/

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11. HealthlinkUSA Emphysema Links Respiration Training Device Attacks emphysema. A new Respiration Training Technique, developed by IntellectBreathing, http://www.healthlinkusa.com/Emphysema.htm

12. National Emphysema Treatment Trial Information about a research study, news room, glossary and resources.Category Health Conditions and Diseases emphysema......NETT is a research study supported by the NHLBI, HCFA, and AHCPR, designed to evaluateif LVRS has a role in the treatment of emphysema. emphysema Awareness. http://www.emphysemastudy.org/

Emphysema Awareness Resources Contact Us The Study Glossary Newsroom Site Map Welcome to the National Emphysema Treatment Trial For patients with emphysema, a form of chronic obstructive pulmonary disease (COPD), inhaling can be as difficult as breathing through a pillow. There is no cure for emphysema, but treatment options are being investigated that may provide a breath of hope. The National Emphysema Treatment Trial (NETT) was established to determine if lung volume reduction surgery (LVRS) is effective in the treatment of emphysema. ABOUT NETT NETT is a clinical research study designed to determine if lung volume reduction surgery ( LVRS ) is effective in the treatment of emphysema . At 19 clinical sites across the United States, the study will enroll 2,500 patients who have been diagnosed with emphysema. All patients will receive medical treatment , with half also undergoing LVRS. NETT is funded and overseen by the National Heart, Lung, and Blood Institute (NHLBI), a component of the National Institutes of Health (NIH), in collaboration with the Health Care Financing Administration (HCFA), which manages Medicare. NAVIGATING THIS WEB SITE This Web site offers you information about emphysema and NETT, as well as an opportunity to have your eligibility determined for NETT. You may:

13. NATIONAL EMPHYSEMA TREATMENT TRIAL The first multi-center clinical trial designed to determine the role, safety, and effectiveness Category Health Conditions and Diseases emphysema...... multicenter clinical trial designed to determine the role, safety, and effectivenessof bilateral lung volume reduction surgery in the treatment of emphysema. http://www.nhlbi.nih.gov/health/prof/lung/nett/lvrsweb.htm

NATIONAL EMPHYSEMA TREATMENT TRIAL (NETT): EVALUATION OF LUNG VOLUME REDUCTION SURGERY FOR EMPHYSEMA What is NETT? Why is NETT Necessary? Background and Rationale NETT Protocol ... List of Participating Centers What is NETT? The National Emphysema Treatment Trial (NETT), supported by the National Heart, Lung, and Blood Institute (NHLBI), the Health Care Financing Administration (HCFA), and the Agency for Health Care Policy and Research (AHCPR), is the first multi-center clinical trial designed to determine the role, safety, and effectiveness of bilateral lung volume reduction surgery (LVRS) in the treatment of emphysema. Emphysema is a chronic lung condition that is a major cause of death and disability in the U.S. If LVRS is found to be beneficial, then a secondary objective will be to develop criteria for identifying patients who are likely to benefit from the procedure. Why is NETT necessary? Return to Top In patients with emphysema, the walls between the tiny air sacs in the lungs are damaged. While healthy lungs expand with each inhalation and collapse with each exhalation, helping to move air in and out lungs damaged by emphysema gradually lose their elasticity, becoming floppy and over-expanded like a spent rubber band. The airways, normally held open by the elastic pull of the lungs, also become floppy and collapse on exhalation. As a result, patients with emphysema have increasing difficulty moving air in and out of their lungs. In Lung Volume Reduction Surgery (LVRS), the size of the lungs is reduced. The theory underlying the surgery is that reducing the lung size will pull open the airways and allow the breathing muscles to return to a more normal and comfortable position, making breathing easier.

14. Emphysema Peruse an overview of this disease affecting the lungs. Research the epidemiology, symptoms, causes, and treatment options. What Is emphysema? emphysema is a condition in which there is overinflation of structures in the lungs known as http://www.cheshire-med.com/programs/pulrehab/emphysema.html

Emphysema From the American Lung Association What Is Emphysema? Emphysema is a condition in which there is over-inflation of structures in the lungs known as alveoli or air sacs. This over-inflation results from a breakdown of the walls of the alveoli, which causes a decrease in respiratory function (the way the lungs work) and often, breathlessness. Early symptoms of emphysema include shortness of breath and cough. How Serious Is Emphysema? Emphysema is a widespread disease of the lungs. In 1993, 1.9 million people in the U.S. had emphysema. It is estimated that 50,000 to 100,000 Americans living today were born with a deficiency of a protein known as alpha 1-antitrypsin (AAT) which can lead to an inherited form of emphysema. Emphysema ranks 15th among chronic conditions that contribute to activity limitations: over 43 percent of individuals with emphysema report that their daily activities have been limited by the disease. Many of the people with emphysema are older men, but the condition is increasing among women. Males with emphysema outnumber females by 22 percent.

15. NHLBI-Funded Emphysema Study Finds Certain Patients At High Risk For Death Follo Contact NHLBI Communications Office (301) 4964236. NHLBI-Funded emphysemaStudy Finds Certain Patients at High Risk for Death Following Lung Surgery. http://www.nhlbi.nih.gov/new/press/01-08-14.htm

NATIONAL INSTITUTES OF HEALTH National Heart, Lung, and Blood Institute EMBARGOED FOR RELEASE Tuesday, August 14, 2001 5:00 p.m. EDT Contact: NHLBI Communications Office NHLBI-Funded Emphysema Study Finds Certain Patients at High Risk for Death Following Lung Surgery Emphysema patients who have severe lung obstruction with either limited ability to exchange gas when breathing or damage that is evenly distributed throughout their lungs receive little benefit from lung volume reduction surgery (LVRS) and are at high risk of death from the procedure, according to early results from the National Emphysema Treatment Trial (NETT). NETT is a five-year, multicenter, randomized study to evaluate the role of LVRS in the treatment of severe emphysema. This is the first time that researchers have identified scientifically based selection criteria for patients seeking LVRS as a potential treatment for advanced emphysema. As a result of the findings, patients with these high-risk characteristics are no longer being enrolled in NETT; however, the study will continue to recruit other eligible patients until its scheduled completion in 2002. "This is exactly the kind of insight we hope to gain from NETT," said Dr. Claude Lenfant, director of the National Heart, Lung, and Blood Institute (NHLBI), the primary sponsor of the study. "Identifying which patients should not undergo this surgery is a key goal of this study. We expect the final results of NETT will guide us further in determining if and when this procedure should be used to treat emphysema."

16. EMPHYSEMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE - Disease Therapies Protocol Detailed definition of this disorder with a look at the causes, symptoms, diagnosis, prevention, complica Category Health Conditions and Diseases......emphysema AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. emphysema ranks fifteenthamong chronic diseases that contribute to limitation of physical activity. http://www.lef.org/protocols/prtcl-046.shtml

LEF Site Search All categories Protocols Health Conditions Products LE Magazine Medical Abstracts What's Hot FDA Information About LEF LEF News Research Health Concerns Funded Research Track Record Innovative Doctors ... Scientific Advisory Free Product Directory Click for a FREE copy of our Product Directory LEF Membership What is LEF? Benefits Become a Member Renewals ... Become a Subscriber Our call center has now expanded its hours Monday thru Friday: 8:30am to 12:00am EST 5:30am to 9:00pm PST Saturday hours are: 9:00am to 8:00pm EST 6:00am to 5:00pm PST Sunday hours are: 11:00am to 7:00pm EST 8:00am to 4:00pm PST If you'd like to order by phone or speak to a live person for help, just call toll free: Customer Service Info Privacy Policy We subscribe to the HONcode principles. Verify here EMPHYSEMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE Abstracts for Protocol Printing? Use this ! Related Products ACETYL L CARNITINE 500 MG 100 CA...

17. Every Breath You Take Information about preventing and treating emphysema from US Food and Drug Administration.Category Health Conditions and Diseases emphysema......When you or someone you love has been diagnosed with emphysema, knowing that helpis available to counter and control its effects provides solace and hope. http://www.fda.gov/fdac/features/1999/299_emph.html

Table of Contents FDA Consumer magazine March-April 1999 Every Breath You Take Preventing and Treating EMPHYSEMA by Carol Lewis We begin life with a breath, and the process continues automatically without a thought. It's only when we can't take a deep breath or, as in Shirley Gooden's case, can't catch our breath at all without effort, that we become aware of how precious easy breathing really is. Gooden, whose breathing is now supplemented with the help of an oxygen tank, was diagnosed with emphysema 14 years ago. Since then, the 68-year-old Bethesda, Md., resident has gradually felt the effects that the debilitating disease has had on her life as well as her lungs. "I'm held back from interacting with my grandchildren, " Gooden says, and like the healthy lungs she used to have, "that's something I can never get back." While it is true that the damage done to Gooden's lungs is not reversible, the disease is manageable, says John S. Saia, M.D., a pulmonary specialist with the Rockville Internal Medicine Group in Maryland, and Gooden's doctor. Saia adds that state-of-the-art medical advances can offer relief from many of the troubling symptoms of emphysema, and help patients breathe easier. What Is Emphysema?

18. Virtual Hospital: ElectricDiffuseLung: The Diagnosis Of Diffuse Lung Disease: Em emphysema and Other Obstructive Lung Diseases. The association betweenexposure to cigarette smoke and emphysema is well documented. http://www.vh.org/adult/provider/radiology/DiffuseLung/Text/Emphysema.html

For Providers ElectricDiffuseLung: The Diagnosis of Diffuse Lung Disease Emphysema and Other Obstructive Lung Diseases Jeffrey R. Galvin, M.D. and Michael P. D'Alessandro, M.D. Peer Review Status: Externally Peer Reviewed by Mosby The assessment of cigarette smokers with dyspnea and airway obstruction is difficult due to the number of primary lung diseases (emphysema, bronchitis, asthma, or bronchiectasis) that can present with a similar constellation of symptoms and objective data. [40] In addition, cardiac failure and pulmonary embolus can mimic primary airway disease. The American Thoracic Society [43] has defined emphysema as a condition of the lung characterized by abnormal, permanent enlargement of airspaces distal to the terminal bronchiole, accompanied by the destruction of their walls, and without obvious fibrosis. The association between exposure to cigarette smoke and emphysema is well documented. [44] However, there also are data suggesting a relationship between fibrosis and smoking. [44, 45] This has raised important questions about the pathogenesis and definition of emphysema. Using a scanning electron microscope, Nagai and Thurlbeck [46] have demonstrated the presence of alveolar wall fibrosis in areas of centrilobular emphysema. Emphysema is classified into three subtypes based on the portion of the acinus that is involved.

19. Facts About Emphysema Information from the American Lung Association of Georgia.Category Health Conditions and Diseases emphysema...... Facts about emphysema. What Is emphysema? emphysema is a condition in which thereis overinflation of structures in the lungs known as alveoli or air sacs. http://abrannen.home.mindspring.com/alag/emphysma.htm

Facts about Emphysema What Is Emphysema? Emphysema is a condition in which there is over-inflation of structures in the lungs known as alveoli or air sacs. This over-inflation results from a breakdown of the walls of the alveoli, which causes a decrease in respiratory function (the way the lungs work) and often, breathlessness. Early symptoms of emphysema include shortness of breath and cough. How Serious Is Emphysema? Emphysema is a widespread disease of the lungs. In 1987, 2.0 million people in the U.S. had emphysema. It is estimated that 70,000 to 100,000 Americans living today were born with a deficiency of a protein known as alpha I-antitrypsin (AAT) which can lead to an inherited form of emphysema. Emphysema ranks ninth among chronic conditions that contribute to lack of activity: Over 42% of individuals with emphysema report that their daily activities have been limited by the disease. Many of the people with emphysema are older men, but the condition is increasing among women. Males with emphysema outnumber females by 64%.. Causes of Emphysema It is known from scientific research that the normal lung has a remarkable balance between two classes of chemicals with opposing action. The lung also has a system of elastic fibers. The fibers allow the lungs to expand and contract. When the chemical balance is altered, the lungs lose the ability to protect themselves against the destruction of these elastic fibers. This is what happens in emphysema.

20. EMedicine - Chronic Obstructive Pulmonary Disease And Emphysema : Article By Pau Chronic Obstructive Pulmonary Disease and emphysema Chronic obstructive pulmonarydisease (COPD) is estimated to affect 32 million persons in the United http://www.emedicine.com/EMERG/topic99.htm

(advertisement) Home Specialties CME PDA ... Patient Education Articles Images CME Patient Education Advanced Search Link to this site Back to: eMedicine Specialties Emergency Medicine Pulmonary Chronic Obstructive Pulmonary Disease and Emphysema Last Updated: July 12, 2002 Rate this Article Email to a Colleague Synonyms and related keywords: COPD AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Paul Kleinschmidt, MD , Staff Physician, Department of Emergency Medicine, Womack Army Medical Center Paul Kleinschmidt, MD, is a member of the following medical societies: American Academy of Emergency Medicine , and Special Operations Medical Association Editor(s): David FM Brown, MD , Instructor, Department of Medicine, Division of Emergency Medicine, Harvard Medical School; Associate Chief, Department of Emergency Medicine, Massachusetts General Hospital; Francisco Talavera, PharmD, PhD , Senior Pharmacy Editor, Pharmacy, eMedicine; Paul Blackburn, DO

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