61. MSN Learning & Research - Hemophilia hemophilia, hereditary blood disease involving the inability of blood to clot, or coagulate, leading to hemorrhage, or bleeding. http://encarta.msn.com/encnet/refpages/RefArticle.aspx?refid=761570021

62. Hemophilia - Bayer Pharmaceutical Home What is hemophilia? Berkeley, CA Clayton, NC Resources Feedback Products. LatestNews Product Literature. Journal of hemophilia Reports. The Parents Resource http://www.hemophiliabayer.com/

Home What is Hemophilia? Berkeley, CA Clayton, NC ... New Hand-Held Computer Technology Improves Management of Chronic, Life-Threatening Bleeding Disorders; Bayer Biological Products Acquires Rights for Use in Hemophilia Clinical Questions? Call our Clinical Communications Dept. (select option #1) Peer Reviewed Literature Bayer sponsored programs Kids On The Block Interactive TeleClinic Product Literature Journal of Hemophilia Reports Parents Empowering Parents The PEP Program Parents' Frequently Asked Questions Patient Notification System PPTA Slide Presentation: "Inside A Bleeding Joint" Glossary of Hemophilia Related Words Children's Activity Book Slide Presentation: "Inside A Bleeding Joint" Links to Fun Stuff Click here for hemophilia treatment product information Home Health Care Providers Parents Children ... Privacy Statement

63. Choice Source Therapeutics Provide hemophilia care for patients. http://www.choicesource.com

About Us Services Contacts Resources About Us Services Contacts Resources ... Español

64. Hemophilia - Bayer Pharmaceutical - What Is Hemophilia? Clinical Questions? Call our Clinical Communications Dept. 1800-288-8371 (selectoption 1). What is hemophilia? hemophilia CARE IN THE UNITED STATES. http://www.hemophiliabayer.com/What_is_Hemophilia_/what_is_hemophilia_.html

Home What is Hemophilia? Berkeley, CA Clayton, NC ... Products Clinical Questions? Call our Clinical Communications Dept. (select option #1) What is Hemophilia? Definition Hemophilia is a genetic disorder characterized by the deficiency or absence of one of the proteins (or factors) in blood plasma that is responsible for clotting. Low levels of one of these plasma proteins result in bleeding and difficulty clotting in the affected individual. There are more than a dozen clotting factors in our bodies. The most common deficiency of a clotting protein is factor VIII although any one of these can be deficient or absent. The second most common deficiency is Factor IX deficiency. There are factor VIII and IX concentrates that are manufactured to treat these two types of hemophilia. Treatment for hemophilia Manufacturers, like Bayer, have developed concentrates containing Factor VIII and IX clotting factors that are used for treatment of persons with hemophilia. These clotting factor concentrates are packaged in a freeze-dried form that requires reconstitution with sterile water before being infused into the vein of a person with hemophilia. Click here for information on Bayer Pharmaceutical's line of hemophilia products.

65. Canadian Hemophila Society: BC Chapter Information about the organization and its mission, news archive, links and contact details. Also an in depth look at the disease itself including management. http://www.hemophiliabc.ca

Home Our Mission Who We Are About Hemophilia News Archive ... Contact Latest News You are invited to join us on Friday, June 20, 2003, when we host the first annual BC Hemophilia Charity Golf Classic We tee off at Swan-E-Set Bay Resort and Country Club with a 12:30 shotgun start. After a round of golf and lunch, the day wraps up in style with a banquet dinner, speeches and charity auction. Come out as an individual golfer or really get into the game and enter your team of four to support the BC Chapter of the Canadian Hemophilia Society. Ongoing Events Our Charity Car Donation Program is a way for you to turn your unwanted vehicle into a cash donation for the Hemophilia Society of BC. A-Part Auto Wrecking will arrange for pick up of your car, processes the sale of your vehicle, and forwards the proceeds directly to Hemophilia BC. For more information please contact: A-Part Auto Wrecking Ltd . 13491 Mitchell Road Richmond, BC, V6V 1M7

66. HSC- Hemophilia Society Of Colorado HSC Home Page click here. http://www.cohemo.org/

HSC Home Page - click here HSC Home Page - click here

67. Tonya's Page This page is dedicated to my son, who has hemophilia. http://members.tripod.com/~TKCDAC/index-2.html

This page has moved to http://members.tripod.com/TKCDAC/index.html Please make a note of

68. Royal Hemophilia Pedigree A Pedigree of hemophilia in the Royal Families of Europe. Selectedmembers of the pedigree I1 = King George III; III-1 and III-2 http://www.people.virginia.edu/~rjh9u/roylhema.html

A Pedigree of Hemophilia in the Royal Families of Europe Selected members of the pedigree I-1 = King George III III-1 and III-2 = Prince Albert and Queen Victoria IV-5 and IV-6 = Alice of Hesse and Ludwig IV of Hesse V-13 and V-14 = Alix and Nicholas II (Tsar of Russia) VI-16 = Alexei VIII-1 = Prince Charles A Case Study of Hemophilia An Alternate Diagnosis World Federation of Hemophilia National Hemophilia Foundation ... The British Monarchy This document maintained by Robert J. Huskey Last updated on August 11, 1998.

69. Gentiva Health Services - Page Not Found Designed to help you understand hemophilia, von Willebrand's disease and other bleeding disorders and provide valuable information. http://www.gentiva.com/consumer/hemophilia/

About Gentiva Services Investor Relations Career Opportunities ... gentiva.com Page Not Found We are sorry, but the URL you requested could not be found. The page you are looking for may have been renamed, moved, or deleted. If you feel you have reached this page in error, please use the Back button of your browser or check the address you entered and try again. If you reached this page from another part of gentiva.com, please let us know so we can fix the problem. Please check the URL for spelling, capitalization, and punctuation errors, and click the "reload" button on your browser. To view a current site map of gentiva.com click here , or to return to the gentiva.com home page click here Company Information Services Investor Relations ... Legal Statement

70. Hemophilia Pedigree A Pedigree of hemophilia. Fortunately, the family shows genetic segregation fora RFLP polymorphism which is tightly linked with the hemophilia gene. http://www.people.virginia.edu/~rjh9u/hemaped1.html

A Pedigree of Hemophilia The sister (II-1) of the boy with hemophilia (II-2) will be getting married soon and wants to know if she is a carrier for the hemophilia allele. Fortunately, the family shows genetic segregation for a RFLP polymorphism which is tightly linked with the hemophilia gene. The unaffected father (I-1) has the 3 kb polymorphism on his X chromosome (F) and must contribute that to each of his daughters. The mother has both the 3 kb (M2) and the 4 kb (M1) polymorphisms, one on each X chromosome. Since the affected son must have received his X chromosome from his mother and he has the 3 kb polymorphism, the hemophilia allele (indicated by a red area on the fragment M2) must be segregating with the 3 kb (M2) polymorphism carried by the mother. So, the ready to be married daughter received the X with the 4 kb polymorphism from her mother and an X with the 3 kb polymorphism from father. Since she didn't receive the 3 kb polymorphism from her mother, she is not a carrier for hemophilia. On the other hand, the other daughter (II-3) is homozygous for the 3 kb polymorphism receiving one copy from her father and the other copy (with the hemophilia allele linked to it) from her mother and she is a carrier for hemophilia.

71. HEMOPHILIA hemophilia. Background hemophilia is the oldest known hereditary bleedingdisorder. There are two types of hemophilia, A and B (Christmas Disease). http://www.nhlbi.nih.gov/health/public/blood/other/hemophel.htm

HEMOPHILIA Background Challenges : The most important challenges facing the hemophilia patient, health care provider, and research community today are: Safety of products used for treatment; Management of the disease including inhibitor formation, irreversible joint damage, and life-threatening hemorrhage; and Progress toward a cure. Safety of Products Used for Treatment : In the past 10 to 15 years, advances in screening of blood donors, laboratory testing of donated blood, and techniques to inactivate viruses in blood and blood products have remarkably increased the safety of blood products used to treat hemophilia. Although treatment-related infection with the AIDS virus or most of the hepatitis viruses is a thing of the past, these measures do not completely avoid viruses such as hepatitis A and parvo virus. These infections are rare; nevertheless, they can pose a threat. Researchers are working to improve procedures to destroy these viruses. To ensure absolute safety from transfusion-transmitted viruses and other agents, hemophiliacs may now be treated with factor VIII which has been produced through biotechnology. This product, recombinant factor VIII, is manufactured by a process entirely free of blood products. It, thus, contains only the factor VIII necessary to treat the disease and none of the other components of blood or attendant unwanted agents. Although the cost of this product exceeds that of the blood-derived product, it is clearly the treatment of choice for those, such as newborns, who have not yet been exposed to blood products. A factor IX product has also been produced by such a process and is currently in clinical trials. Once this product is shown to be safe and effective, all hemophiliacs will have available a treatment for bleeding which is totally free of any contaminating agents.

72. Haemostasis Forum Dedicated to supplying information on haemophilia to medical and health care professionals, providing an excellent opportunity to interact with worldwide specialists in the field of haematology. http://www.hemophilia-forum.org/

This is a web site dedicated to supplying information on haemophilia to medical and health care professionals, providing an excellent opportunity to interact with worldwide specialists in the field of haematology. Each month the contents of these pages are updated and reviewed by a panel of independent haemophilia specialists. Please click on Faculty Info. This forum is supported by an educational grant from Novo Nordisk A/S. If you would like to access this site, please click on 'Register Now' and submit your details. If you have already registered, please enter your username and password and click on 'accept'. Enter your details here please User name: Password: Cancel Accept Preview this site Register ... Forgot Password

73. Hemophilia Update: 1997 hemophilia UPDATE 1997. Background effective. Antibody inhibitorsare more likely to occur in individuals with severe hemophilia. http://www.nhlbi.nih.gov/health/public/blood/other/hemo_97.htm

HEMOPHILIA UPDATE: 1997 Background Advances in treatment over the last three decades have permitted a near-normal lifestyle and life-span for many individuals with hemophilia. The introduction of factor VIII concentrate products in the 1970s allowed treatment at home and largely replaced the need for transfusion of whole blood or plasma in the hospital. An unfortunate result of increased freedom from bleeding as a cause of disability and death was infection with hepatitis from products made from pooled plasma. This culminated in the early 1980s with the unexpected and devastating infection of about 70 % of severe hemophiliac patients with HIV, the cause of AIDS. Since then, the development and improvement of methods for inactivating viruses with lipid envelopes in plasma, including factor VIII and IX concentrates, has improved the safety of transfused products to the point where the threat of infection with HIV, hepatitis B(HBV) or hepatitis C (HCV) viruses has been essentially eliminated. Safety of Products Used in Treatment Over the last few years, improved procedures have led to high purity plasma-derived factor VIII and factor IX products which appear to be safer when subjected to viral inactivation procedures than were the previous lower potency materials. "First generation" recombinant factor VIII, produced without human plasma, became available in 1992. This added a measure of safety especially from non-enveloped viruses, although the need for human albumen to stabilize the factor left a tiny and currently hypothetical risk of human infectious agent transmission. The first recombinant factor IX preparation is now in clinical trials. It is a "second generation" product which is manufactured and packaged without any human or animal plasma proteins. A similarly produced factor VIII concentrate is under development.

74. Index Florida Chapter Of The National hemophilia Foundation, Inc. This pageis designed to pass information on to our community and to http://www.geocities.com/HotSprings/1809/

Florida Chapter National Hemophilia Foundation March is Hemophilia Awareness Month Links For Your Information Florida Chapter Newsletter Anyone not receiving our award winning newsletter can e-mail us your name and address at hemoph5011@aol.com . This newsletter has important and updated information plus activities going on around the state. The newsletter and this website are for you, so any input or links you feel should be on our list, please e-mail them to us including any of your personal webpages. If there is a picture or article you would like to include in our newsletter please e-mail it and it will get to our editor. We can always use your help. Don't forget to see who our sponsors are and visit their sites including Amazon.com and CD Now. Upcoming NHF Meetings Camp Application Calendar Of Events Chapter's Officers and Board Members ... Medical and Reference Links Florida Chapter Home Office Numbers: Home Office: 1-727-856-7057 Fax: 1-727-856-2257 Toll Free - 1-888-880-8330 Board Members Photo Gallery Links to Donations: Everytime you make a purchase through our Amazon link or CD NOW located below, a percentage of your purchase is donated to our Chapter. Thank you in advance!

75. HAVEN HAVEN is an independent organization in Northwestern PA. W Provides patients and their families with information about their condition, treatment options and patient rights. http://members.tripod.com/haven8361/

var TlxPgNm='index'; HAVEN Hemophilia And VonWillebrand's Education Network Mission Vision History Bleeding Disorders Information ... Related Links Welcome to the HAVEN web site. HAVEN evolved from a support group started by the mother of a hemophiliac in Erie, PA in 1997. The support group now includes other affected individuals and families and is gaining the interest and support of the Erie community. The support group organized themselves and identified certain needs within the local Bleeding Disorders Community. HAVEN was created to help address those needs. HAVEN is an independent bleeding disorders association. We seek to provide patients and their families information about their condition, treatment options and patient rights. HAVEN can provide the patients and families with a variety of contacts within the hemophilia community. HAVEN (Hemophilia and von Willebrand’s Education Network) held the 2nd Thank you to the following for their support of the M a r d ... l: Click above for new photos added, 8/27/02 Aventis Behring L.L.C.

76. Jared Pedroza http://www.hemophiliautah.org/

Contact Information Work Experience Software Hardware Operating Systems Education Download .pdf

77. Bayer at Bayer Biological Products have been dedicated to developing and producing noveltreatments that extend and enhance the lives of people with hemophilia. http://www.bayer-hemophilia-awards.com/

For more than 30 years, scientists and researchers at Bayer Biological Products have been dedicated to developing and producing novel treatments that extend and enhance the lives of people with hemophilia. Bayer believes the Hemophilia Awards Program can improve the lives of patients with hemophilia by supporting research and education worldwide. The next steps for the next generation

78. GeneReviews: Hemophilia A Your browser does not support HTML frames so you must view hemophilia Ain a slightly less readable form. Please follow this link to do so. http://www.geneclinics.org/profiles/hemo-a/

Your browser does not support HTML frames so you must view Hemophilia A in a slightly less readable form. Please follow this link to do so.

79. Inheritance Of Hemophilia Xlinked Inheritance hemophilia. Legend hemophilia is a sex linked traitin humans, inherited in the same way white eye color in Drosophila. http://www.accessexcellence.org/AB/GG/x-linked.html

X-linked Inheritance: Hemophilia Legend: Hemophilia is a sex linked trait in humans, inherited in the same way white eye color in Drosophila. Males are hemizygous, receiving their only X chromosome from their mother. Females are heterozygous, inheriting X chromosomes from both parents. If a female has a defective gene on one of her two X chromosomes, she will be protected from its effects by the normal gene on her second X chromosome. If a male has a mutant X and a normal Y chromosome, he will be affected by a X-linked disease. A son, whose mother has two normal alleles, will not be affected by hemophilia even if the father has the disease and the defective gene. A daughter of the same parents will be a heterozygous carrier. A heterozygous carrier mother and a normal father pass the gene for hemophilia on to possibly one- half of their children. Half the daughters will be carriers and half the sons will be hemophilic. The rest of the siblings will be normal. Daughters, as long as one parent is genotypically normal, can only be carriers. The normal gene on the second X chromosome counteracts the defect and the daughters do not suffer from the trait. If a son receives the defective gene from his mother, he will be hemophilic because the Y chromosome can not counteract the defective gene located on his X chromosome. Graphics Gallery Index About Biotech Index Search Home Questions Email This Link

80. Hemophilia Association Of New Jersey - Hemophilia, Bleeding Disorders The hemophilia Association of New Jersey offers assistance to persons withhemophilia and their families from our office located in East Brunswick. http://www.hanj.org/

You are visitor since 01.01.98. An Website. The Hemophilia Association of New Jersey was founded in August 1971 by 10 concerned families, and offers assistance to persons with hemophilia and their families from our office located in East Brunswick, New Jersey We hope that you find our web site informative as well as comprehensive. Don't forget to periodically check out the "What's New" page to keep up to date on current events that affect the hemophilia community. If you have questions, suggestions or need further information, please feel free to call us or E-mail us All information that appears on the Hemophilia Association of New Jersey website, including links to other websites, is for your general information only. The Hemophilia Association of New Jersey makes no endorsements for or against medical treatments and/or therapies. Please consult your physician, or local treatment center before pursuing any course of treatment. E-mail the Web Master

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